diff --git a/crates/ruff_linter/resources/test/fixtures/pyupgrade/UP041.py b/crates/ruff_linter/resources/test/fixtures/pyupgrade/UP041.py
new file mode 100644
index 0000000000000..2c30094f59a08
--- /dev/null
+++ b/crates/ruff_linter/resources/test/fixtures/pyupgrade/UP041.py
@@ -0,0 +1,68 @@
+import asyncio, socket
+# These should be fixed
+try:
+    pass
+except asyncio.TimeoutError:
+    pass
+
+try:
+    pass
+except socket.timeout:
+    pass
+
+# Should NOT be in parentheses when replaced
+
+try:
+    pass
+except (asyncio.TimeoutError,):
+    pass
+
+try:
+    pass
+except (socket.timeout,):
+    pass
+
+try:
+    pass
+except (asyncio.TimeoutError, socket.timeout,):
+    pass
+
+# Should be kept in parentheses (because multiple)
+
+try:
+    pass
+except (asyncio.TimeoutError, socket.timeout, KeyError, TimeoutError):
+    pass
+
+# First should change, second should not
+
+from .mmap import error
+try:
+    pass
+except (asyncio.TimeoutError, error):
+    pass
+
+# These should not change
+
+from foo import error
+
+try:
+    pass
+except (TimeoutError, error):
+    pass
+
+try:
+    pass
+except:
+    pass
+
+try:
+    pass
+except TimeoutError:
+    pass
+
+
+try:
+    pass
+except (TimeoutError, KeyError):
+    pass
diff --git a/crates/ruff_linter/src/checkers/ast/analyze/expression.rs b/crates/ruff_linter/src/checkers/ast/analyze/expression.rs
index 62878e61aceaf..aa000bcf5d569 100644
--- a/crates/ruff_linter/src/checkers/ast/analyze/expression.rs
+++ b/crates/ruff_linter/src/checkers/ast/analyze/expression.rs
@@ -466,6 +466,11 @@ pub(crate) fn expression(expr: &Expr, checker: &mut Checker) {
             if checker.enabled(Rule::OSErrorAlias) {
                 pyupgrade::rules::os_error_alias_call(checker, func);
             }
+            if checker.enabled(Rule::TimeoutErrorAlias) {
+                if checker.settings.target_version >= PythonVersion::Py310 {
+                    pyupgrade::rules::timeout_error_alias_call(checker, func);
+                }
+            }
             if checker.enabled(Rule::NonPEP604Isinstance) {
                 if checker.settings.target_version >= PythonVersion::Py310 {
                     pyupgrade::rules::use_pep604_isinstance(checker, expr, func, args);
diff --git a/crates/ruff_linter/src/checkers/ast/analyze/statement.rs b/crates/ruff_linter/src/checkers/ast/analyze/statement.rs
index 0a567da1c4961..51863307ea29d 100644
--- a/crates/ruff_linter/src/checkers/ast/analyze/statement.rs
+++ b/crates/ruff_linter/src/checkers/ast/analyze/statement.rs
@@ -1006,6 +1006,13 @@ pub(crate) fn statement(stmt: &Stmt, checker: &mut Checker) {
                     pyupgrade::rules::os_error_alias_raise(checker, item);
                 }
             }
+            if checker.enabled(Rule::TimeoutErrorAlias) {
+                if checker.settings.target_version >= PythonVersion::Py310 {
+                    if let Some(item) = exc {
+                        pyupgrade::rules::timeout_error_alias_raise(checker, item);
+                    }
+                }
+            }
             if checker.enabled(Rule::RaiseVanillaClass) {
                 if let Some(expr) = exc {
                     tryceratops::rules::raise_vanilla_class(checker, expr);
@@ -1304,6 +1311,11 @@ pub(crate) fn statement(stmt: &Stmt, checker: &mut Checker) {
             if checker.enabled(Rule::OSErrorAlias) {
                 pyupgrade::rules::os_error_alias_handlers(checker, handlers);
             }
+            if checker.enabled(Rule::TimeoutErrorAlias) {
+                if checker.settings.target_version >= PythonVersion::Py310 {
+                    pyupgrade::rules::timeout_error_alias_handlers(checker, handlers);
+                }
+            }
             if checker.enabled(Rule::PytestAssertInExcept) {
                 flake8_pytest_style::rules::assert_in_exception_handler(checker, handlers);
             }
diff --git a/crates/ruff_linter/src/codes.rs b/crates/ruff_linter/src/codes.rs
index 8df3ad330448e..9e0ceccfd7b9e 100644
--- a/crates/ruff_linter/src/codes.rs
+++ b/crates/ruff_linter/src/codes.rs
@@ -500,6 +500,7 @@ pub fn code_to_rule(linter: Linter, code: &str) -> Option<(RuleGroup, Rule)> {
         (Pyupgrade, "038") => (RuleGroup::Stable, rules::pyupgrade::rules::NonPEP604Isinstance),
         (Pyupgrade, "039") => (RuleGroup::Stable, rules::pyupgrade::rules::UnnecessaryClassParentheses),
         (Pyupgrade, "040") => (RuleGroup::Stable, rules::pyupgrade::rules::NonPEP695TypeAlias),
+        (Pyupgrade, "041") => (RuleGroup::Preview, rules::pyupgrade::rules::TimeoutErrorAlias),
 
         // pydocstyle
         (Pydocstyle, "100") => (RuleGroup::Stable, rules::pydocstyle::rules::UndocumentedPublicModule),
diff --git a/crates/ruff_linter/src/rules/pyupgrade/mod.rs b/crates/ruff_linter/src/rules/pyupgrade/mod.rs
index d9ba5d890a2ba..987e82608e03b 100644
--- a/crates/ruff_linter/src/rules/pyupgrade/mod.rs
+++ b/crates/ruff_linter/src/rules/pyupgrade/mod.rs
@@ -60,6 +60,7 @@ mod tests {
     #[test_case(Rule::ReplaceStdoutStderr, Path::new("UP022.py"))]
     #[test_case(Rule::ReplaceUniversalNewlines, Path::new("UP021.py"))]
     #[test_case(Rule::SuperCallWithParameters, Path::new("UP008.py"))]
+    #[test_case(Rule::TimeoutErrorAlias, Path::new("UP041.py"))]
     #[test_case(Rule::TypeOfPrimitive, Path::new("UP003.py"))]
     #[test_case(Rule::TypingTextStrAlias, Path::new("UP019.py"))]
     #[test_case(Rule::UTF8EncodingDeclaration, Path::new("UP009_0.py"))]
diff --git a/crates/ruff_linter/src/rules/pyupgrade/rules/mod.rs b/crates/ruff_linter/src/rules/pyupgrade/rules/mod.rs
index 0a924c145120d..aa6a60732fbed 100644
--- a/crates/ruff_linter/src/rules/pyupgrade/rules/mod.rs
+++ b/crates/ruff_linter/src/rules/pyupgrade/rules/mod.rs
@@ -20,6 +20,7 @@ pub(crate) use redundant_open_modes::*;
 pub(crate) use replace_stdout_stderr::*;
 pub(crate) use replace_universal_newlines::*;
 pub(crate) use super_call_with_parameters::*;
+pub(crate) use timeout_error_alias::*;
 pub(crate) use type_of_primitive::*;
 pub(crate) use typing_text_str_alias::*;
 pub(crate) use unicode_kind_prefix::*;
@@ -59,6 +60,7 @@ mod redundant_open_modes;
 mod replace_stdout_stderr;
 mod replace_universal_newlines;
 mod super_call_with_parameters;
+mod timeout_error_alias;
 mod type_of_primitive;
 mod typing_text_str_alias;
 mod unicode_kind_prefix;
diff --git a/crates/ruff_linter/src/rules/pyupgrade/rules/timeout_error_alias.rs b/crates/ruff_linter/src/rules/pyupgrade/rules/timeout_error_alias.rs
new file mode 100644
index 0000000000000..1bb999f96d651
--- /dev/null
+++ b/crates/ruff_linter/src/rules/pyupgrade/rules/timeout_error_alias.rs
@@ -0,0 +1,192 @@
+use ruff_python_ast::{self as ast, ExceptHandler, Expr, ExprContext};
+use ruff_text_size::{Ranged, TextRange};
+
+use crate::fix::edits::pad;
+use ruff_diagnostics::{AlwaysFixableViolation, Diagnostic, Edit, Fix};
+use ruff_macros::{derive_message_formats, violation};
+use ruff_python_ast::call_path::compose_call_path;
+use ruff_python_semantic::SemanticModel;
+
+use crate::checkers::ast::Checker;
+use crate::settings::types::PythonVersion;
+
+/// ## What it does
+/// Checks for uses of exceptions that alias `TimeoutError`.
+///
+/// ## Why is this bad?
+/// `TimeoutError` is the builtin error type used for exceptions when a system
+/// function timed out at the system level.
+///
+/// In Python 3.10, `socket.timeout` was aliased to `TimeoutError`. In Python
+/// 3.11, `asyncio.TimeoutError` was aliased to `TimeoutError`.
+///
+/// These aliases remain in place for compatibility with older versions of
+/// Python, but may be removed in future versions.
+///
+/// Prefer using `TimeoutError` directly, as it is more idiomatic and future-proof.
+///
+/// ## Example
+/// ```python
+/// raise asyncio.TimeoutError
+/// ```
+///
+/// Use instead:
+/// ```python
+/// raise TimeoutError
+/// ```
+///
+/// ## References
+/// - [Python documentation: `TimeoutError`](https://docs.python.org/3/library/exceptions.html#TimeoutError)
+#[violation]
+pub struct TimeoutErrorAlias {
+    name: Option<String>,
+}
+
+impl AlwaysFixableViolation for TimeoutErrorAlias {
+    #[derive_message_formats]
+    fn message(&self) -> String {
+        format!("Replace aliased errors with `TimeoutError`")
+    }
+
+    fn fix_title(&self) -> String {
+        let TimeoutErrorAlias { name } = self;
+        match name {
+            None => "Replace with builtin `TimeoutError`".to_string(),
+            Some(name) => format!("Replace `{name}` with builtin `TimeoutError`"),
+        }
+    }
+}
+
+/// Return `true` if an [`Expr`] is an alias of `TimeoutError`.
+fn is_alias(expr: &Expr, semantic: &SemanticModel, target_version: PythonVersion) -> bool {
+    semantic.resolve_call_path(expr).is_some_and(|call_path| {
+        if target_version >= PythonVersion::Py311 {
+            matches!(call_path.as_slice(), [""] | ["asyncio", "TimeoutError"])
+        } else {
+            matches!(
+                call_path.as_slice(),
+                [""] | ["asyncio", "TimeoutError"] | ["socket", "timeout"]
+            )
+        }
+    })
+}
+
+/// Return `true` if an [`Expr`] is `TimeoutError`.
+fn is_timeout_error(expr: &Expr, semantic: &SemanticModel) -> bool {
+    semantic
+        .resolve_call_path(expr)
+        .is_some_and(|call_path| matches!(call_path.as_slice(), ["", "TimeoutError"]))
+}
+
+/// Create a [`Diagnostic`] for a single target, like an [`Expr::Name`].
+fn atom_diagnostic(checker: &mut Checker, target: &Expr) {
+    let mut diagnostic = Diagnostic::new(
+        TimeoutErrorAlias {
+            name: compose_call_path(target),
+        },
+        target.range(),
+    );
+    if checker.semantic().is_builtin("TimeoutError") {
+        diagnostic.set_fix(Fix::safe_edit(Edit::range_replacement(
+            "TimeoutError".to_string(),
+            target.range(),
+        )));
+    }
+    checker.diagnostics.push(diagnostic);
+}
+
+/// Create a [`Diagnostic`] for a tuple of expressions.
+fn tuple_diagnostic(checker: &mut Checker, tuple: &ast::ExprTuple, aliases: &[&Expr]) {
+    let mut diagnostic = Diagnostic::new(TimeoutErrorAlias { name: None }, tuple.range());
+    if checker.semantic().is_builtin("TimeoutError") {
+        // Filter out any `TimeoutErrors` aliases.
+        let mut remaining: Vec<Expr> = tuple
+            .elts
+            .iter()
+            .filter_map(|elt| {
+                if aliases.contains(&elt) {
+                    None
+                } else {
+                    Some(elt.clone())
+                }
+            })
+            .collect();
+
+        // If `TimeoutError` itself isn't already in the tuple, add it.
+        if tuple
+            .elts
+            .iter()
+            .all(|elt| !is_timeout_error(elt, checker.semantic()))
+        {
+            let node = ast::ExprName {
+                id: "TimeoutError".into(),
+                ctx: ExprContext::Load,
+                range: TextRange::default(),
+            };
+            remaining.insert(0, node.into());
+        }
+
+        let content = if remaining.len() == 1 {
+            "TimeoutError".to_string()
+        } else {
+            let node = ast::ExprTuple {
+                elts: remaining,
+                ctx: ExprContext::Load,
+                range: TextRange::default(),
+            };
+            format!("({})", checker.generator().expr(&node.into()))
+        };
+
+        diagnostic.set_fix(Fix::safe_edit(Edit::range_replacement(
+            pad(content, tuple.range(), checker.locator()),
+            tuple.range(),
+        )));
+    }
+    checker.diagnostics.push(diagnostic);
+}
+
+/// UP041
+pub(crate) fn timeout_error_alias_handlers(checker: &mut Checker, handlers: &[ExceptHandler]) {
+    for handler in handlers {
+        let ExceptHandler::ExceptHandler(ast::ExceptHandlerExceptHandler { type_, .. }) = handler;
+        let Some(expr) = type_.as_ref() else {
+            continue;
+        };
+        match expr.as_ref() {
+            Expr::Name(_) | Expr::Attribute(_) => {
+                if is_alias(expr, checker.semantic(), checker.settings.target_version) {
+                    atom_diagnostic(checker, expr);
+                }
+            }
+            Expr::Tuple(tuple) => {
+                // List of aliases to replace with `TimeoutError`.
+                let mut aliases: Vec<&Expr> = vec![];
+                for elt in &tuple.elts {
+                    if is_alias(elt, checker.semantic(), checker.settings.target_version) {
+                        aliases.push(elt);
+                    }
+                }
+                if !aliases.is_empty() {
+                    tuple_diagnostic(checker, tuple, &aliases);
+                }
+            }
+            _ => {}
+        }
+    }
+}
+
+/// UP041
+pub(crate) fn timeout_error_alias_call(checker: &mut Checker, func: &Expr) {
+    if is_alias(func, checker.semantic(), checker.settings.target_version) {
+        atom_diagnostic(checker, func);
+    }
+}
+
+/// UP041
+pub(crate) fn timeout_error_alias_raise(checker: &mut Checker, expr: &Expr) {
+    if matches!(expr, Expr::Name(_) | Expr::Attribute(_)) {
+        if is_alias(expr, checker.semantic(), checker.settings.target_version) {
+            atom_diagnostic(checker, expr);
+        }
+    }
+}
diff --git a/crates/ruff_linter/src/rules/pyupgrade/snapshots/ruff_linter__rules__pyupgrade__tests__UP041.py.snap b/crates/ruff_linter/src/rules/pyupgrade/snapshots/ruff_linter__rules__pyupgrade__tests__UP041.py.snap
new file mode 100644
index 0000000000000..9c288554d26d2
--- /dev/null
+++ b/crates/ruff_linter/src/rules/pyupgrade/snapshots/ruff_linter__rules__pyupgrade__tests__UP041.py.snap
@@ -0,0 +1,104 @@
+---
+source: crates/ruff_linter/src/rules/pyupgrade/mod.rs
+---
+UP041.py:5:8: UP041 [*] Replace aliased errors with `TimeoutError`
+  |
+3 | try:
+4 |     pass
+5 | except asyncio.TimeoutError:
+  |        ^^^^^^^^^^^^^^^^^^^^ UP041
+6 |     pass
+  |
+  = help: Replace `asyncio.TimeoutError` with builtin `TimeoutError`
+
+ℹ Fix
+2 2 | # These should be fixed
+3 3 | try:
+4 4 |     pass
+5   |-except asyncio.TimeoutError:
+  5 |+except TimeoutError:
+6 6 |     pass
+7 7 | 
+8 8 | try:
+
+UP041.py:17:8: UP041 [*] Replace aliased errors with `TimeoutError`
+   |
+15 | try:
+16 |     pass
+17 | except (asyncio.TimeoutError,):
+   |        ^^^^^^^^^^^^^^^^^^^^^^^ UP041
+18 |     pass
+   |
+   = help: Replace with builtin `TimeoutError`
+
+ℹ Fix
+14 14 | 
+15 15 | try:
+16 16 |     pass
+17    |-except (asyncio.TimeoutError,):
+   17 |+except TimeoutError:
+18 18 |     pass
+19 19 | 
+20 20 | try:
+
+UP041.py:27:8: UP041 [*] Replace aliased errors with `TimeoutError`
+   |
+25 | try:
+26 |     pass
+27 | except (asyncio.TimeoutError, socket.timeout,):
+   |        ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ UP041
+28 |     pass
+   |
+   = help: Replace with builtin `TimeoutError`
+
+ℹ Fix
+24 24 | 
+25 25 | try:
+26 26 |     pass
+27    |-except (asyncio.TimeoutError, socket.timeout,):
+   27 |+except (TimeoutError, socket.timeout):
+28 28 |     pass
+29 29 | 
+30 30 | # Should be kept in parentheses (because multiple)
+
+UP041.py:34:8: UP041 [*] Replace aliased errors with `TimeoutError`
+   |
+32 | try:
+33 |     pass
+34 | except (asyncio.TimeoutError, socket.timeout, KeyError, TimeoutError):
+   |        ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ UP041
+35 |     pass
+   |
+   = help: Replace with builtin `TimeoutError`
+
+ℹ Fix
+31 31 | 
+32 32 | try:
+33 33 |     pass
+34    |-except (asyncio.TimeoutError, socket.timeout, KeyError, TimeoutError):
+   34 |+except (socket.timeout, KeyError, TimeoutError):
+35 35 |     pass
+36 36 | 
+37 37 | # First should change, second should not
+
+UP041.py:42:8: UP041 [*] Replace aliased errors with `TimeoutError`
+   |
+40 | try:
+41 |     pass
+42 | except (asyncio.TimeoutError, error):
+   |        ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ UP041
+43 |     pass
+   |
+   = help: Replace with builtin `TimeoutError`
+
+ℹ Fix
+39 39 | from .mmap import error
+40 40 | try:
+41 41 |     pass
+42    |-except (asyncio.TimeoutError, error):
+   42 |+except (TimeoutError, error):
+43 43 |     pass
+44 44 | 
+45 45 | # These should not change
+
+
diff --git a/ruff.schema.json b/ruff.schema.json
index b861d4bf2457f..1886b55e838d2 100644
--- a/ruff.schema.json
+++ b/ruff.schema.json
@@ -3536,6 +3536,7 @@
         "UP039",
         "UP04",
         "UP040",
+        "UP041",
         "W",
         "W1",
         "W19",