diff --git a/lib/adapters/xhr.js b/lib/adapters/xhr.js
index d52d4b29bc..92f0daf259 100644
--- a/lib/adapters/xhr.js
+++ b/lib/adapters/xhr.js
@@ -66,11 +66,10 @@ export default isXHRAdapterSupported && function (config) {
     if (utils.isFormData(requestData)) {
       if (platform.hasStandardBrowserEnv || platform.hasStandardBrowserWebWorkerEnv) {
         requestHeaders.setContentType(false); // Let the browser set it
-      } else if(!requestHeaders.getContentType(/^\s*multipart\/form-data/)){
-        requestHeaders.setContentType('multipart/form-data'); // mobile/desktop app frameworks
-      } else if(utils.isString(contentType = requestHeaders.getContentType())){
+      } else if ((contentType = requestHeaders.getContentType()) !== false) {
         // fix semicolon duplication issue for ReactNative FormData implementation
-        requestHeaders.setContentType(contentType.replace(/^\s*(multipart\/form-data);+/, '$1'))
+        const [type, ...tokens] = contentType ? contentType.split(';').map(token => token.trim()).filter(Boolean) : [];
+        requestHeaders.setContentType([type || 'multipart/form-data', ...tokens].join('; '));
       }
     }