diff --git a/src/client/actions/ActionsManager.js b/src/client/actions/ActionsManager.js
index 0f3f53169f7a..bcb9f2744ed2 100644
--- a/src/client/actions/ActionsManager.js
+++ b/src/client/actions/ActionsManager.js
@@ -4,6 +4,7 @@ class ActionsManager {
   constructor(client) {
     this.client = client;
 
+    this.register(require('./ApplicationCommandPermissionsUpdate'));
     this.register(require('./AutoModerationActionExecution'));
     this.register(require('./AutoModerationRuleCreate'));
     this.register(require('./AutoModerationRuleDelete'));
diff --git a/src/client/actions/ApplicationCommandPermissionsUpdate.js b/src/client/actions/ApplicationCommandPermissionsUpdate.js
new file mode 100644
index 000000000000..0aa518cafd4d
--- /dev/null
+++ b/src/client/actions/ApplicationCommandPermissionsUpdate.js
@@ -0,0 +1,34 @@
+'use strict';
+
+const Action = require('./Action');
+const { Events } = require('../../util/Constants');
+
+/**
+ * The data received in the {@link Client#event:applicationCommandPermissionsUpdate} event
+ * @typedef {Object} ApplicationCommandPermissionsUpdateData
+ * @property {Snowflake} id The id of the command or global entity that was updated
+ * @property {Snowflake} guildId The id of the guild in which permissions were updated
+ * @property {Snowflake} applicationId The id of the application that owns the command or entity being updated
+ * @property {ApplicationCommandPermissions[]} permissions The updated permissions
+ */
+
+class ApplicationCommandPermissionsUpdateAction extends Action {
+  handle(data) {
+    const client = this.client;
+    /**
+     * Emitted whenever permissions for an application command in a guild were updated.
+     * <warn>This includes permission updates for other applications in addition to the logged in client,
+     * check `data.applicationId` to verify which application the update is for</warn>
+     * @event Client#applicationCommandPermissionsUpdate
+     * @param {ApplicationCommandPermissionsUpdateData} data The updated permissions
+     */
+    client.emit(Events.APPLICATION_COMMAND_PERMISSIONS_UPDATE, {
+      permissions: data.permissions,
+      id: data.id,
+      guildId: data.guild_id,
+      applicationId: data.application_id,
+    });
+  }
+}
+
+module.exports = ApplicationCommandPermissionsUpdateAction;
diff --git a/src/client/websocket/handlers/APPLICATION_COMMAND_PERMISSIONS_UPDATE.js b/src/client/websocket/handlers/APPLICATION_COMMAND_PERMISSIONS_UPDATE.js
new file mode 100644
index 000000000000..73d4ec47f464
--- /dev/null
+++ b/src/client/websocket/handlers/APPLICATION_COMMAND_PERMISSIONS_UPDATE.js
@@ -0,0 +1,5 @@
+'use strict';
+
+module.exports = (client, packet) => {
+  client.actions.ApplicationCommandPermissionsUpdate.handle(packet.d);
+};
diff --git a/src/client/websocket/handlers/index.js b/src/client/websocket/handlers/index.js
index 7a0926499b69..62e43a991996 100644
--- a/src/client/websocket/handlers/index.js
+++ b/src/client/websocket/handlers/index.js
@@ -6,6 +6,7 @@ const handlers = Object.fromEntries([
   ['APPLICATION_COMMAND_CREATE', require('./APPLICATION_COMMAND_CREATE')],
   ['APPLICATION_COMMAND_DELETE', require('./APPLICATION_COMMAND_DELETE')],
   ['APPLICATION_COMMAND_UPDATE', require('./APPLICATION_COMMAND_UPDATE')],
+  ['APPLICATION_COMMAND_PERMISSIONS_UPDATE', require('./APPLICATION_COMMAND_PERMISSIONS_UPDATE')],
   ['AUTO_MODERATION_ACTION_EXECUTION', require('./AUTO_MODERATION_ACTION_EXECUTION')],
   ['AUTO_MODERATION_RULE_CREATE', require('./AUTO_MODERATION_RULE_CREATE')],
   ['AUTO_MODERATION_RULE_DELETE', require('./AUTO_MODERATION_RULE_DELETE')],
diff --git a/src/structures/GuildAuditLogs.js b/src/structures/GuildAuditLogs.js
index 2a736f51795c..ed4bbfa95caf 100644
--- a/src/structures/GuildAuditLogs.js
+++ b/src/structures/GuildAuditLogs.js
@@ -1,6 +1,7 @@
 'use strict';
 
 const { Collection } = require('@discordjs/collection');
+const ApplicationCommand = require('./ApplicationCommand');
 const AutoModerationRule = require('./AutoModerationRule');
 const { GuildScheduledEvent } = require('./GuildScheduledEvent');
 const Integration = require('./Integration');
@@ -27,6 +28,7 @@ const Util = require('../util/Util');
  * * STICKER
  * * THREAD
  * * GUILD_SCHEDULED_EVENT
+ * * APPLICATION_COMMAND
  * * AUTO_MODERATION
  * @typedef {string} AuditLogTargetType
  */
@@ -51,6 +53,7 @@ const Targets = {
   STAGE_INSTANCE: 'STAGE_INSTANCE',
   STICKER: 'STICKER',
   THREAD: 'THREAD',
+  APPLICATION_COMMAND: 'APPLICATION_COMMAND',
   AUTO_MODERATION: 'AUTO_MODERATION',
   UNKNOWN: 'UNKNOWN',
 };
@@ -105,6 +108,7 @@ const Targets = {
  * * THREAD_CREATE: 110
  * * THREAD_UPDATE: 111
  * * THREAD_DELETE: 112
+ * * APPLICATION_COMMAND_PERMISSION_UPDATE: 121
  * * AUTO_MODERATION_RULE_CREATE: 140
  * * AUTO_MODERATION_RULE_UPDATE: 141
  * * AUTO_MODERATION_RULE_DELETE: 142
@@ -169,6 +173,7 @@ const Actions = {
   THREAD_CREATE: 110,
   THREAD_UPDATE: 111,
   THREAD_DELETE: 112,
+  APPLICATION_COMMAND_PERMISSION_UPDATE: 121,
   AUTO_MODERATION_RULE_CREATE: 140,
   AUTO_MODERATION_RULE_UPDATE: 141,
   AUTO_MODERATION_RULE_DELETE: 142,
@@ -208,6 +213,17 @@ class GuildAuditLogs {
       }
     }
 
+    /**
+     * Cached application commands, includes application commands from other applications
+     * @type {Collection<Snowflake, ApplicationCommand>}
+     * @private
+     */
+    this.applicationCommands = new Collection();
+    if (data.application_commands) {
+      for (const command of data.application_commands) {
+        this.applicationCommands.set(command.id, new ApplicationCommand(guild.client, command, guild));
+      }
+    }
     /**
      * Cached auto moderation rules.
      * @type {Collection<Snowflake, AutoModerationRule>}
@@ -255,11 +271,12 @@ class GuildAuditLogs {
    * * A sticker
    * * A guild scheduled event
    * * A thread
+   * * An application command
    * * An auto moderation rule
    * * An object with an id key if target was deleted
    * * An object where the keys represent either the new value or the old value
    * @typedef {?(Object|Guild|Channel|User|Role|Invite|Webhook|GuildEmoji|Message|Integration|StageInstance|Sticker|
-   * GuildScheduledEvent|AutoModerationRule)} AuditLogEntryTarget
+   * GuildScheduledEvent|ApplicationCommand|AutoModerationRule)} AuditLogEntryTarget
    */
 
   /**
@@ -281,6 +298,7 @@ class GuildAuditLogs {
     if (target < 100) return Targets.STICKER;
     if (target < 110) return Targets.GUILD_SCHEDULED_EVENT;
     if (target < 120) return Targets.THREAD;
+    if (target < 130) return Targets.APPLICATION_COMMAND;
     if (target >= 140 && target < 150) return Targets.AUTO_MODERATION;
     return Targets.UNKNOWN;
   }
@@ -366,6 +384,7 @@ class GuildAuditLogs {
         Actions.STICKER_UPDATE,
         Actions.GUILD_SCHEDULED_EVENT_UPDATE,
         Actions.THREAD_UPDATE,
+        Actions.APPLICATION_COMMAND_PERMISSION_UPDATE,
         Actions.AUTO_MODERATION_RULE_UPDATE,
       ].includes(action)
     ) {
@@ -506,6 +525,11 @@ class GuildAuditLogsEntry {
           channel: guild.client.channels.cache.get(data.options?.channel_id) ?? { id: data.options?.channel_id },
         };
         break;
+      case Actions.APPLICATION_COMMAND_PERMISSION_UPDATE:
+        this.extra = {
+          applicationId: data.options.application_id,
+        };
+        break;
       case Actions.AUTO_MODERATION_BLOCK_MESSAGE:
       case Actions.AUTO_MODERATION_FLAG_TO_CHANNEL:
       case Actions.AUTO_MODERATION_USER_COMMUNICATION_DISABLED:
@@ -641,6 +665,8 @@ class GuildAuditLogsEntry {
             { id: data.target_id, guild_id: guild.id },
           ),
         );
+    } else if (targetType === Targets.APPLICATION_COMMAND) {
+      this.target = logs?.applicationCommands.get(data.target_id) ?? { id: data.target_id };
     } else if (targetType === Targets.AUTO_MODERATION) {
       this.target =
         guild.autoModerationRules.cache.get(data.target_id) ??
diff --git a/src/util/Constants.js b/src/util/Constants.js
index cf70715960db..06a1f1720132 100644
--- a/src/util/Constants.js
+++ b/src/util/Constants.js
@@ -174,6 +174,7 @@ exports.Opcodes = {
  * * APPLICATION_COMMAND_CREATE: applicationCommandCreate (deprecated)
  * * APPLICATION_COMMAND_DELETE: applicationCommandDelete (deprecated)
  * * APPLICATION_COMMAND_UPDATE: applicationCommandUpdate (deprecated)
+ * * APPLICATION_COMMAND_PERMISSIONS_UPDATE: applicationCommandPermissionsUpdate
  * * AUTO_MODERATION_ACTION_EXECUTION: autoModerationActionExecution
  * * AUTO_MODERATION_RULE_CREATE: autoModerationRuleCreate
  * * AUTO_MODERATION_RULE_DELETE: autoModerationRuleDelete
@@ -256,6 +257,7 @@ exports.Events = {
   APPLICATION_COMMAND_CREATE: 'applicationCommandCreate',
   APPLICATION_COMMAND_DELETE: 'applicationCommandDelete',
   APPLICATION_COMMAND_UPDATE: 'applicationCommandUpdate',
+  APPLICATION_COMMAND_PERMISSIONS_UPDATE: 'applicationCommandPermissionsUpdate',
   AUTO_MODERATION_ACTION_EXECUTION: 'autoModerationActionExecution',
   AUTO_MODERATION_RULE_CREATE: 'autoModerationRuleCreate',
   AUTO_MODERATION_RULE_DELETE: 'autoModerationRuleDelete',
@@ -368,6 +370,7 @@ exports.PartialTypes = keyMirror(['USER', 'CHANNEL', 'GUILD_MEMBER', 'MESSAGE',
  * * RESUMED
  * * APPLICATION_COMMAND_CREATE (deprecated)
  * * APPLICATION_COMMAND_DELETE (deprecated)
+ * * APPLICATION_COMMAND_PERMISSIONS_UPDATE
  * * APPLICATION_COMMAND_UPDATE (deprecated)
  * * GUILD_CREATE
  * * GUILD_DELETE
@@ -428,6 +431,7 @@ exports.WSEvents = keyMirror([
   'APPLICATION_COMMAND_CREATE',
   'APPLICATION_COMMAND_DELETE',
   'APPLICATION_COMMAND_UPDATE',
+  'APPLICATION_COMMAND_PERMISSIONS_UPDATE',
   'GUILD_CREATE',
   'GUILD_DELETE',
   'GUILD_UPDATE',
diff --git a/typings/index.d.ts b/typings/index.d.ts
index e4547b92fe99..63a0067bf9eb 100644
--- a/typings/index.d.ts
+++ b/typings/index.d.ts
@@ -4178,6 +4178,13 @@ export interface ApplicationCommandPermissionData {
   permission: boolean;
 }
 
+export interface ApplicationCommandPermissionsUpdateData {
+  permissions: ApplicationCommandPermissions;
+  id: Snowflake;
+  guildId: Snowflake;
+  applicationId: Snowflake;
+}
+
 export interface ApplicationCommandPermissions extends ApplicationCommandPermissionData {
   type: ApplicationCommandPermissionType;
 }
@@ -4441,6 +4448,7 @@ export interface ClientEvents extends BaseClientEvents {
   applicationCommandDelete: [command: ApplicationCommand];
   /** @deprecated See [this issue](https://github.com/discord/discord-api-docs/issues/3690) for more information. */
   applicationCommandUpdate: [oldCommand: ApplicationCommand | null, newCommand: ApplicationCommand];
+  applicationCommandPermissionsUpdate: [data: ApplicationCommandPermissionsUpdateData];
   autoModerationActionExecution: [autoModerationActionExecution: AutoModerationActionExecution];
   autoModerationRuleCreate: [autoModerationRule: AutoModerationRule];
   autoModerationRuleDelete: [autoModerationRule: AutoModerationRule];
@@ -4719,6 +4727,7 @@ export interface ConstantsEvents {
   APPLICATION_COMMAND_CREATE: 'applicationCommandCreate';
   /** @deprecated See [this issue](https://github.com/discord/discord-api-docs/issues/3690) for more information. */
   APPLICATION_COMMAND_DELETE: 'applicationCommandDelete';
+  APPLICATION_COMMAND_PERMISSIONS_UPDATE: 'applicationCommandPermissionsUpdate';
   /** @deprecated See [this issue](https://github.com/discord/discord-api-docs/issues/3690) for more information. */
   APPLICATION_COMMAND_UPDATE: 'applicationCommandUpdate';
   AUTO_MODERATION_ACTION_EXECUTION: 'autoModerationActionExecution';
@@ -5081,6 +5090,7 @@ interface GuildAuditLogsTypes {
   THREAD_CREATE: ['THREAD', 'CREATE'];
   THREAD_UPDATE: ['THREAD', 'UPDATE'];
   THREAD_DELETE: ['THREAD', 'DELETE'];
+  APPLICATION_COMMAND_PERMISSION_UPDATE: ['APPLICATION_COMMAND_PERMISSION', 'UPDATE'];
   AUTO_MODERATION_RULE_CREATE: ['AUTO_MODERATION', 'CREATE'];
   AUTO_MODERATION_RULE_UPDATE: ['AUTO_MODERATION', 'UPDATE'];
   AUTO_MODERATION_RULE_DELETE: ['AUTO_MODERATION', 'DELETE'];
@@ -5137,6 +5147,7 @@ export interface GuildAuditLogsIds {
   110: 'THREAD_CREATE';
   111: 'THREAD_UPDATE';
   112: 'THREAD_DELETE';
+  121: 'APPLICATION_COMMAND_PERMISSION_UPDATE';
   140: 'AUTO_MODERATION_RULE_CREATE';
   141: 'AUTO_MODERATION_RULE_UPDATE';
   142: 'AUTO_MODERATION_RULE_DELETE';
@@ -5177,6 +5188,9 @@ export interface GuildAuditLogsEntryExtraField {
   STAGE_INSTANCE_CREATE: StageChannel | { id: Snowflake };
   STAGE_INSTANCE_DELETE: StageChannel | { id: Snowflake };
   STAGE_INSTANCE_UPDATE: StageChannel | { id: Snowflake };
+  APPLICATION_COMMAND_PERMISSION_UPDATE: {
+    applicationId: Snowflake;
+  };
   AUTO_MODERATION_BLOCK_MESSAGE: {
     autoModerationRuleName: string;
     autoModerationRuleTriggerType: AutoModerationRuleTriggerType;
@@ -5203,6 +5217,7 @@ export interface GuildAuditLogsEntryTargetField<TActionType extends GuildAuditLo
   STAGE_INSTANCE: StageInstance;
   STICKER: Sticker;
   GUILD_SCHEDULED_EVENT: GuildScheduledEvent;
+  APPLICATION_COMMAND: ApplicationCommand | { id: Snowflake };
   AUTO_MODERATION: AutoModerationRule;
 }
 
@@ -6421,6 +6436,7 @@ export type WSEventType =
   | 'RESUMED'
   | 'APPLICATION_COMMAND_CREATE'
   | 'APPLICATION_COMMAND_DELETE'
+  | 'APPLICATION_COMMAND_PERMISSIONS_UPDATE'
   | 'APPLICATION_COMMAND_UPDATE'
   | 'GUILD_CREATE'
   | 'GUILD_DELETE'