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An irreproducibility of some results #54

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PKazakova opened this issue Jun 11, 2020 · 1 comment
Open

An irreproducibility of some results #54

PKazakova opened this issue Jun 11, 2020 · 1 comment

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@PKazakova
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PKazakova commented Jun 11, 2020

Hello,

I decided to check an reproducibility of results HLA-typing by xHLA. I run xHLA on one sample 10 times and , unfortunately, I got different results. I can suggest that this is due to some difficult regions for alignment (e.g. HLA-B*44:138Q: Evidence for a Confined Deletion and Recombination Events in an Otherwise Unaffected HLA-haplotype). But I can't understand which result is correct and which result isn't. For illustration this case I attach output files for 2 samples with 2 different results.
Can you explain why I get different results?

Thanks,
Polina.
Screenshot_1
Screenshot_2

@serge2016
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This is important to me too. Is it possible to fix it?

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