diff --git a/CHANGELOG.md b/CHANGELOG.md
index 80867e863a56..d54ee20c7d7a 100644
--- a/CHANGELOG.md
+++ b/CHANGELOG.md
@@ -7,6 +7,7 @@
 ### Fixes
 
 - `[babel-plugin-jest-hoist]` Support imported `jest` in mock factory ([#13188](https://github.com/facebook/jest/pull/13188))
+- `[jest-runtime]` Support `jest.resetModules()` with ESM ([#13211](https://github.com/facebook/jest/pull/13211))
 
 ### Chore & Maintenance
 
diff --git a/e2e/__tests__/__snapshots__/nativeEsm.test.ts.snap b/e2e/__tests__/__snapshots__/nativeEsm.test.ts.snap
index 1e6cd80fa82e..4324b26d16c4 100644
--- a/e2e/__tests__/__snapshots__/nativeEsm.test.ts.snap
+++ b/e2e/__tests__/__snapshots__/nativeEsm.test.ts.snap
@@ -10,7 +10,7 @@ Ran all test suites matching /native-esm-deep-cjs-reexport.test.js/i."
 
 exports[`runs test with native ESM 1`] = `
 "Test Suites: 1 passed, 1 total
-Tests:       33 passed, 33 total
+Tests:       34 passed, 34 total
 Snapshots:   0 total
 Time:        <<REPLACED>>
 Ran all test suites matching /native-esm.test.js/i."
diff --git a/e2e/native-esm/__tests__/native-esm.test.js b/e2e/native-esm/__tests__/native-esm.test.js
index 0f59cadcc12d..767f1cbf27c7 100644
--- a/e2e/native-esm/__tests__/native-esm.test.js
+++ b/e2e/native-esm/__tests__/native-esm.test.js
@@ -46,6 +46,7 @@ test('should support importing node core modules', () => {
   expect(JSON.parse(readFileSync(packageJsonPath, 'utf8'))).toEqual({
     devDependencies: {
       'discord.js': '14.3.0',
+      yargs: '^17.5.1',
     },
     jest: {
       testEnvironment: 'node',
@@ -300,3 +301,24 @@ test('can mock "data:" URI module', async () => {
   const mocked = await import(dataModule);
   expect(mocked.foo).toBe('bar');
 });
+
+test('can import with module reset', async () => {
+  const {default: yargs} = await import('yargs');
+  const {default: yargsAgain} = await import('yargs');
+
+  expect(yargs).toBe(yargsAgain);
+
+  let args = yargs().parse([]);
+
+  expect(args._).toEqual([]);
+
+  jestObject.resetModules();
+
+  const {default: yargsYetAgain} = await import('yargs');
+
+  expect(yargs).not.toBe(yargsYetAgain);
+
+  args = yargsYetAgain().parse([]);
+
+  expect(args._).toEqual([]);
+});
diff --git a/e2e/native-esm/package.json b/e2e/native-esm/package.json
index 7e5307b71f1d..60993c0776ca 100644
--- a/e2e/native-esm/package.json
+++ b/e2e/native-esm/package.json
@@ -1,7 +1,8 @@
 {
   "type": "module",
   "devDependencies": {
-    "discord.js": "14.3.0"
+    "discord.js": "14.3.0",
+    "yargs": "^17.5.1"
   },
   "jest": {
     "testEnvironment": "node",
diff --git a/e2e/native-esm/yarn.lock b/e2e/native-esm/yarn.lock
index 737d96c077d9..227ec7c5703f 100644
--- a/e2e/native-esm/yarn.lock
+++ b/e2e/native-esm/yarn.lock
@@ -48,12 +48,12 @@ __metadata:
   linkType: hard
 
 "@sapphire/shapeshift@npm:^3.5.1":
-  version: 3.5.1
-  resolution: "@sapphire/shapeshift@npm:3.5.1"
+  version: 3.6.0
+  resolution: "@sapphire/shapeshift@npm:3.6.0"
   dependencies:
     fast-deep-equal: ^3.1.3
     lodash.uniqwith: ^4.5.0
-  checksum: caecfef844c9e43e921a5051da888fae7da8980bfd9f9bb4f7fee85931d40929ffb9b6dfae464c0dccee61e56f7698f998e4d9a54d25f35fad39a51ba1a4f391
+  checksum: 31b426424d064c516144c6eda07dfa0e44d7cbb8309dde919b923aa6ae939faac6384fa4d08db391a8da11efa3a83c18c9be1ebd053ba29403e61f5e2450b788
   languageName: node
   linkType: hard
 
@@ -72,9 +72,9 @@ __metadata:
   linkType: hard
 
 "@types/node@npm:*":
-  version: 18.7.13
-  resolution: "@types/node@npm:18.7.13"
-  checksum: 45431e7e89ecaf85c7d2c180d801c132a7c59e2f8ad578726b6d71cc74e3267c18f9ccdcad738bc0479790c078f0c79efb0e58da2c6be535c15995dbb19050c9
+  version: 18.7.14
+  resolution: "@types/node@npm:18.7.14"
+  checksum: 99cf28ff854100158de875cca23c7acc3cc01dfee526a52b90b7f36767c821bcbaf2be0a98a70f06f3b78f3c60639168ff949d725b61e2e124f9f71f1fb8043d
   languageName: node
   linkType: hard
 
@@ -87,10 +87,53 @@ __metadata:
   languageName: node
   linkType: hard
 
+"ansi-regex@npm:^5.0.1":
+  version: 5.0.1
+  resolution: "ansi-regex@npm:5.0.1"
+  checksum: 2aa4bb54caf2d622f1afdad09441695af2a83aa3fe8b8afa581d205e57ed4261c183c4d3877cee25794443fde5876417d859c108078ab788d6af7e4fe52eb66b
+  languageName: node
+  linkType: hard
+
+"ansi-styles@npm:^4.0.0":
+  version: 4.3.0
+  resolution: "ansi-styles@npm:4.3.0"
+  dependencies:
+    color-convert: ^2.0.1
+  checksum: 513b44c3b2105dd14cc42a19271e80f386466c4be574bccf60b627432f9198571ebf4ab1e4c3ba17347658f4ee1711c163d574248c0c1cdc2d5917a0ad582ec4
+  languageName: node
+  linkType: hard
+
+"cliui@npm:^7.0.2":
+  version: 7.0.4
+  resolution: "cliui@npm:7.0.4"
+  dependencies:
+    string-width: ^4.2.0
+    strip-ansi: ^6.0.0
+    wrap-ansi: ^7.0.0
+  checksum: ce2e8f578a4813806788ac399b9e866297740eecd4ad1823c27fd344d78b22c5f8597d548adbcc46f0573e43e21e751f39446c5a5e804a12aace402b7a315d7f
+  languageName: node
+  linkType: hard
+
+"color-convert@npm:^2.0.1":
+  version: 2.0.1
+  resolution: "color-convert@npm:2.0.1"
+  dependencies:
+    color-name: ~1.1.4
+  checksum: 79e6bdb9fd479a205c71d89574fccfb22bd9053bd98c6c4d870d65c132e5e904e6034978e55b43d69fcaa7433af2016ee203ce76eeba9cfa554b373e7f7db336
+  languageName: node
+  linkType: hard
+
+"color-name@npm:~1.1.4":
+  version: 1.1.4
+  resolution: "color-name@npm:1.1.4"
+  checksum: b0445859521eb4021cd0fb0cc1a75cecf67fceecae89b63f62b201cca8d345baf8b952c966862a9d9a2632987d4f6581f0ec8d957dfacece86f0a7919316f610
+  languageName: node
+  linkType: hard
+
 "discord-api-types@npm:^0.37.3":
-  version: 0.37.4
-  resolution: "discord-api-types@npm:0.37.4"
-  checksum: 18b74acfcd5f6c554668eb5cb31a5db9076dfb5cb6b5c538a342ab9d22816644bada22a66285468fe7dd9980287921d5d50ba3b11cc8e391fe4f09e761bcd179
+  version: 0.37.5
+  resolution: "discord-api-types@npm:0.37.5"
+  checksum: 10a23b813d9a30d836aa27169f768883eeed971ab67e58325ff272bfe6b63b169d727ae983d7c1b69c7e0b02ed9072e66e79319ce48174b36cd4a2a5fafe2e9f
   languageName: node
   linkType: hard
 
@@ -113,6 +156,20 @@ __metadata:
   languageName: node
   linkType: hard
 
+"emoji-regex@npm:^8.0.0":
+  version: 8.0.0
+  resolution: "emoji-regex@npm:8.0.0"
+  checksum: d4c5c39d5a9868b5fa152f00cada8a936868fd3367f33f71be515ecee4c803132d11b31a6222b2571b1e5f7e13890156a94880345594d0ce7e3c9895f560f192
+  languageName: node
+  linkType: hard
+
+"escalade@npm:^3.1.1":
+  version: 3.1.1
+  resolution: "escalade@npm:3.1.1"
+  checksum: a3e2a99f07acb74b3ad4989c48ca0c3140f69f923e56d0cba0526240ee470b91010f9d39001f2a4a313841d237ede70a729e92125191ba5d21e74b106800b133
+  languageName: node
+  linkType: hard
+
 "fast-deep-equal@npm:^3.1.3":
   version: 3.1.3
   resolution: "fast-deep-equal@npm:3.1.3"
@@ -131,6 +188,13 @@ __metadata:
   languageName: node
   linkType: hard
 
+"get-caller-file@npm:^2.0.5":
+  version: 2.0.5
+  resolution: "get-caller-file@npm:2.0.5"
+  checksum: b9769a836d2a98c3ee734a88ba712e62703f1df31b94b784762c433c27a386dd6029ff55c2a920c392e33657d80191edbf18c61487e198844844516f843496b9
+  languageName: node
+  linkType: hard
+
 "ieee754@npm:^1.2.1":
   version: 1.2.1
   resolution: "ieee754@npm:1.2.1"
@@ -145,6 +209,13 @@ __metadata:
   languageName: node
   linkType: hard
 
+"is-fullwidth-code-point@npm:^3.0.0":
+  version: 3.0.0
+  resolution: "is-fullwidth-code-point@npm:3.0.0"
+  checksum: 44a30c29457c7fb8f00297bce733f0a64cd22eca270f83e58c105e0d015e45c019491a4ab2faef91ab51d4738c670daff901c799f6a700e27f7314029e99e348
+  languageName: node
+  linkType: hard
+
 "lodash.snakecase@npm:^4.1.1":
   version: 4.1.1
   resolution: "lodash.snakecase@npm:4.1.1"
@@ -186,11 +257,19 @@ __metadata:
   languageName: node
   linkType: hard
 
+"require-directory@npm:^2.1.1":
+  version: 2.1.1
+  resolution: "require-directory@npm:2.1.1"
+  checksum: fb47e70bf0001fdeabdc0429d431863e9475e7e43ea5f94ad86503d918423c1543361cc5166d713eaa7029dd7a3d34775af04764bebff99ef413111a5af18c80
+  languageName: node
+  linkType: hard
+
 "root-workspace-0b6124@workspace:.":
   version: 0.0.0-use.local
   resolution: "root-workspace-0b6124@workspace:."
   dependencies:
     discord.js: 14.3.0
+    yargs: ^17.5.1
   languageName: unknown
   linkType: soft
 
@@ -201,6 +280,17 @@ __metadata:
   languageName: node
   linkType: hard
 
+"string-width@npm:^4.1.0, string-width@npm:^4.2.0, string-width@npm:^4.2.3":
+  version: 4.2.3
+  resolution: "string-width@npm:4.2.3"
+  dependencies:
+    emoji-regex: ^8.0.0
+    is-fullwidth-code-point: ^3.0.0
+    strip-ansi: ^6.0.1
+  checksum: e52c10dc3fbfcd6c3a15f159f54a90024241d0f149cf8aed2982a2d801d2e64df0bf1dc351cf8e95c3319323f9f220c16e740b06faecd53e2462df1d2b5443fb
+  languageName: node
+  linkType: hard
+
 "string_decoder@npm:^1.1.1":
   version: 1.3.0
   resolution: "string_decoder@npm:1.3.0"
@@ -210,6 +300,15 @@ __metadata:
   languageName: node
   linkType: hard
 
+"strip-ansi@npm:^6.0.0, strip-ansi@npm:^6.0.1":
+  version: 6.0.1
+  resolution: "strip-ansi@npm:6.0.1"
+  dependencies:
+    ansi-regex: ^5.0.1
+  checksum: f3cd25890aef3ba6e1a74e20896c21a46f482e93df4a06567cebf2b57edabb15133f1f94e57434e0a958d61186087b1008e89c94875d019910a213181a14fc8c
+  languageName: node
+  linkType: hard
+
 "strtok3@npm:^7.0.0-alpha.9":
   version: 7.0.0
   resolution: "strtok3@npm:7.0.0"
@@ -258,6 +357,17 @@ __metadata:
   languageName: node
   linkType: hard
 
+"wrap-ansi@npm:^7.0.0":
+  version: 7.0.0
+  resolution: "wrap-ansi@npm:7.0.0"
+  dependencies:
+    ansi-styles: ^4.0.0
+    string-width: ^4.1.0
+    strip-ansi: ^6.0.0
+  checksum: a790b846fd4505de962ba728a21aaeda189b8ee1c7568ca5e817d85930e06ef8d1689d49dbf0e881e8ef84436af3a88bc49115c2e2788d841ff1b8b5b51a608b
+  languageName: node
+  linkType: hard
+
 "ws@npm:^8.8.1":
   version: 8.8.1
   resolution: "ws@npm:8.8.1"
@@ -272,3 +382,32 @@ __metadata:
   checksum: 2152cf862cae0693f3775bc688a6afb2e989d19d626d215e70f5fcd8eb55b1c3b0d3a6a4052905ec320e2d7734e20aeedbf9744496d62f15a26ad79cf4cf7dae
   languageName: node
   linkType: hard
+
+"y18n@npm:^5.0.5":
+  version: 5.0.8
+  resolution: "y18n@npm:5.0.8"
+  checksum: 54f0fb95621ee60898a38c572c515659e51cc9d9f787fb109cef6fde4befbe1c4602dc999d30110feee37456ad0f1660fa2edcfde6a9a740f86a290999550d30
+  languageName: node
+  linkType: hard
+
+"yargs-parser@npm:^21.0.0":
+  version: 21.1.1
+  resolution: "yargs-parser@npm:21.1.1"
+  checksum: ed2d96a616a9e3e1cc7d204c62ecc61f7aaab633dcbfab2c6df50f7f87b393993fe6640d017759fe112d0cb1e0119f2b4150a87305cc873fd90831c6a58ccf1c
+  languageName: node
+  linkType: hard
+
+"yargs@npm:^17.5.1":
+  version: 17.5.1
+  resolution: "yargs@npm:17.5.1"
+  dependencies:
+    cliui: ^7.0.2
+    escalade: ^3.1.1
+    get-caller-file: ^2.0.5
+    require-directory: ^2.1.1
+    string-width: ^4.2.3
+    y18n: ^5.0.5
+    yargs-parser: ^21.0.0
+  checksum: 00d58a2c052937fa044834313f07910fd0a115dec5ee35919e857eeee3736b21a4eafa8264535800ba8bac312991ce785ecb8a51f4d2cc8c4676d865af1cfbde
+  languageName: node
+  linkType: hard
diff --git a/packages/jest-runtime/src/index.ts b/packages/jest-runtime/src/index.ts
index 4541cd44d6e0..639ccc9371c3 100644
--- a/packages/jest-runtime/src/index.ts
+++ b/packages/jest-runtime/src/index.ts
@@ -1109,6 +1109,7 @@ export default class Runtime {
     this._mockRegistry.clear();
     this._moduleRegistry.clear();
     this._esmoduleRegistry.clear();
+    this._fileTransformsMutex.clear();
     this._cjsNamedExports.clear();
     this._moduleMockRegistry.clear();
     this._cacheFS.clear();
@@ -1278,7 +1279,6 @@ export default class Runtime {
     this._sourceMapRegistry.clear();
 
     this._fileTransforms.clear();
-    this._fileTransformsMutex.clear();
     this.jestObjectCaches.clear();
 
     this._v8CoverageSources?.clear();