diff --git a/CHANGELOG.md b/CHANGELOG.md
index 4a8c3863378b..c583e938da01 100644
--- a/CHANGELOG.md
+++ b/CHANGELOG.md
@@ -45,6 +45,7 @@
 - `[jest-config]` Pass `moduleTypes` to `ts-node` to enforce CJS when transpiling ([#12397](https://github.com/facebook/jest/pull/12397))
 - `[jest-config, jest-haste-map]` Allow searching for tests in `node_modules` by exposing `retainAllFiles` ([#11084](https://github.com/facebook/jest/pull/11084))
 - `[jest-core]` [**BREAKING**] Exit with status `1` if no tests are found with `--findRelatedTests` flag ([#12487](https://github.com/facebook/jest/pull/12487))
+- `[jest-each]` `%#` is not replaced with index of the test case ([#12517](https://github.com/facebook/jest/pull/12517))
 - `[jest-environment-jsdom]` Make `jsdom` accessible to extending environments again ([#12232](https://github.com/facebook/jest/pull/12232))
 - `[jest-environment-jsdom]` Log JSDOM errors more cleanly ([#12386](https://github.com/facebook/jest/pull/12386))
 - `[@jest/expect-utils]` [**BREAKING**] Fix false positives when looking for `undefined` prop ([#8923](https://github.com/facebook/jest/pull/8923))
diff --git a/packages/jest-each/src/__tests__/array.test.ts b/packages/jest-each/src/__tests__/array.test.ts
index a7eb3e0e11f4..b89e31f49d32 100644
--- a/packages/jest-each/src/__tests__/array.test.ts
+++ b/packages/jest-each/src/__tests__/array.test.ts
@@ -368,6 +368,52 @@ describe('jest-each', () => {
           undefined,
         );
       });
+
+      test('calls global with title containing param values when using %#', () => {
+        const globalTestMocks = getGlobalTestMocks();
+        const eachObject = each.withGlobal(globalTestMocks)([
+          {name: 'foo'},
+          {name: 'bar'},
+        ]);
+        const testFunction = get(eachObject, keyPath);
+        testFunction('expected index: %#', () => {});
+
+        const globalMock = get(globalTestMocks, keyPath);
+        expect(globalMock).toHaveBeenCalledTimes(2);
+        expect(globalMock).toHaveBeenCalledWith(
+          'expected index: 0',
+          expectFunction,
+          undefined,
+        );
+        expect(globalMock).toHaveBeenCalledWith(
+          'expected index: 1',
+          expectFunction,
+          undefined,
+        );
+      });
+
+      test('calls global with title containing param values when using $#', () => {
+        const globalTestMocks = getGlobalTestMocks();
+        const eachObject = each.withGlobal(globalTestMocks)([
+          {name: 'foo'},
+          {name: 'bar'},
+        ]);
+        const testFunction = get(eachObject, keyPath);
+        testFunction('expected index: $#', () => {});
+
+        const globalMock = get(globalTestMocks, keyPath);
+        expect(globalMock).toHaveBeenCalledTimes(2);
+        expect(globalMock).toHaveBeenCalledWith(
+          'expected index: 0',
+          expectFunction,
+          undefined,
+        );
+        expect(globalMock).toHaveBeenCalledWith(
+          'expected index: 1',
+          expectFunction,
+          undefined,
+        );
+      });
     });
   });
 
diff --git a/packages/jest-each/src/table/array.ts b/packages/jest-each/src/table/array.ts
index a4fb9d5d0c63..14bc5df89e07 100644
--- a/packages/jest-each/src/table/array.ts
+++ b/packages/jest-each/src/table/array.ts
@@ -13,7 +13,7 @@ import type {EachTests} from '../bind';
 import type {Templates} from './interpolation';
 import {interpolateVariables} from './interpolation';
 
-const SUPPORTED_PLACEHOLDERS = /%[sdifjoOp]/g;
+const SUPPORTED_PLACEHOLDERS = /%[sdifjoOp#]/g;
 const PRETTY_PLACEHOLDER = '%p';
 const INDEX_PLACEHOLDER = '%#';
 const PLACEHOLDER_PREFIX = '%';