diff --git a/.github/workflows/main.yml b/.github/workflows/main.yml
index 2b779279fdc..27b25fd7228 100644
--- a/.github/workflows/main.yml
+++ b/.github/workflows/main.yml
@@ -27,6 +27,8 @@ jobs:
           "windows-py37",
           "windows-py37-pluggy",
           "windows-py38",
+          "windows-py39",
+          "windows-py310",
 
           "ubuntu-py36",
           "ubuntu-py37",
@@ -34,6 +36,7 @@ jobs:
           "ubuntu-py37-freeze",
           "ubuntu-py38",
           "ubuntu-py39",
+          "ubuntu-py310",
           "ubuntu-pypy3",
 
           "macos-py37",
@@ -62,6 +65,14 @@ jobs:
             os: windows-latest
             tox_env: "py38-unittestextras"
             use_coverage: true
+          - name: "windows-py39"
+            python: "3.9"
+            os: windows-latest
+            tox_env: "py39-xdist"
+          - name: "windows-py310"
+            python: "3.10-dev"
+            os: windows-latest
+            tox_env: "py310-xdist"
 
           - name: "ubuntu-py36"
             python: "3.6"
@@ -88,6 +99,10 @@ jobs:
             python: "3.9"
             os: ubuntu-latest
             tox_env: "py39-xdist"
+          - name: "ubuntu-py310"
+            python: "3.10-dev"
+            os: ubuntu-latest
+            tox_env: "py310-xdist"
           - name: "ubuntu-pypy3"
             python: "pypy3"
             os: ubuntu-latest
diff --git a/.pre-commit-config.yaml b/.pre-commit-config.yaml
index 68cc3273bba..00115989a97 100644
--- a/.pre-commit-config.yaml
+++ b/.pre-commit-config.yaml
@@ -42,8 +42,7 @@ repos:
     rev: v1.11.0
     hooks:
     -   id: setup-cfg-fmt
-        # TODO: when upgrading setup-cfg-fmt this can be removed
-        args: [--max-py-version=3.9]
+        args: [--max-py-version=3.10]
 -   repo: https://github.com/pre-commit/pygrep-hooks
     rev: v1.6.0
     hooks:
diff --git a/changelog/8494.feature.rst b/changelog/8494.feature.rst
new file mode 100644
index 00000000000..eca51d0deb9
--- /dev/null
+++ b/changelog/8494.feature.rst
@@ -0,0 +1 @@
+Python 3.10 is now supported.
diff --git a/pyproject.toml b/pyproject.toml
index dd4be6c22d5..dc26b4d8ddf 100644
--- a/pyproject.toml
+++ b/pyproject.toml
@@ -26,6 +26,8 @@ filterwarnings = [
     # produced by older pyparsing<=2.2.0.
     "default:Using or importing the ABCs:DeprecationWarning:pyparsing.*",
     "default:the imp module is deprecated in favour of importlib:DeprecationWarning:nose.*",
+    # distutils is deprecated in 3.10, scheduled for removal in 3.12
+    "ignore:The distutils package is deprecated:DeprecationWarning",
     # produced by python3.6/site.py itself (3.6.7 on Travis, could not trigger it with 3.6.8)."
     "ignore:.*U.*mode is deprecated:DeprecationWarning:(?!(pytest|_pytest))",
     # produced by pytest-xdist
diff --git a/setup.cfg b/setup.cfg
index 14fdb6df5c0..cfd1f724d63 100644
--- a/setup.cfg
+++ b/setup.cfg
@@ -21,6 +21,7 @@ classifiers =
     Programming Language :: Python :: 3.7
     Programming Language :: Python :: 3.8
     Programming Language :: Python :: 3.9
+    Programming Language :: Python :: 3.10
     Topic :: Software Development :: Libraries
     Topic :: Software Development :: Testing
     Topic :: Utilities
diff --git a/tox.ini b/tox.ini
index f0cfaa460fb..1413feb229d 100644
--- a/tox.ini
+++ b/tox.ini
@@ -9,6 +9,7 @@ envlist =
     py37
     py38
     py39
+    py310
     pypy3
     py37-{pexpect,xdist,unittestextras,numpy,pluggymaster}
     doctesting