diff --git a/lib/tsc.js b/lib/tsc.js
index 8abe56b22a74c..50c0b1f54f56a 100644
--- a/lib/tsc.js
+++ b/lib/tsc.js
@@ -67,7 +67,7 @@ var __generator = (this && this.__generator) || function (thisArg, body) {
 var ts;
 (function (ts) {
     ts.versionMajorMinor = "4.1";
-    ts.version = "4.1.5";
+    ts.version = "4.1.6";
     var NativeCollections;
     (function (NativeCollections) {
         function tryGetNativeMap() {
@@ -4448,8 +4448,8 @@ var ts;
                 },
                 getFileSize: function (path) {
                     try {
-                        var stat = _fs.statSync(path);
-                        if (stat.isFile()) {
+                        var stat = statSync(path);
+                        if (stat === null || stat === void 0 ? void 0 : stat.isFile()) {
                             return stat.size;
                         }
                     }
@@ -4494,6 +4494,9 @@ var ts;
                 }
             };
             return nodeSystem;
+            function statSync(path) {
+                return _fs.statSync(path, { throwIfNoEntry: false });
+            }
             function enableCPUProfiler(path, cb) {
                 if (activeSession) {
                     cb();
@@ -4539,19 +4542,20 @@ var ts;
                 if (activeSession && activeSession !== "stopping") {
                     var s_1 = activeSession;
                     activeSession.post("Profiler.stop", function (err, _a) {
+                        var _b;
                         var profile = _a.profile;
                         if (!err) {
                             try {
-                                if (_fs.statSync(profilePath).isDirectory()) {
+                                if ((_b = statSync(profilePath)) === null || _b === void 0 ? void 0 : _b.isDirectory()) {
                                     profilePath = _path.join(profilePath, (new Date()).toISOString().replace(/:/g, "-") + "+P" + process.pid + ".cpuprofile");
                                 }
                             }
-                            catch (_b) {
+                            catch (_c) {
                             }
                             try {
                                 _fs.mkdirSync(_path.dirname(profilePath), { recursive: true });
                             }
-                            catch (_c) {
+                            catch (_d) {
                             }
                             _fs.writeFileSync(profilePath, JSON.stringify(cleanupPaths(profile)));
                         }
@@ -4740,7 +4744,10 @@ var ts;
                         if (typeof dirent === "string" || dirent.isSymbolicLink()) {
                             var name = ts.combinePaths(path, entry);
                             try {
-                                stat = _fs.statSync(name);
+                                stat = statSync(name);
+                                if (!stat) {
+                                    continue;
+                                }
                             }
                             catch (e) {
                                 continue;
@@ -4771,7 +4778,10 @@ var ts;
                 var originalStackTraceLimit = Error.stackTraceLimit;
                 Error.stackTraceLimit = 0;
                 try {
-                    var stat = _fs.statSync(path);
+                    var stat = statSync(path);
+                    if (!stat) {
+                        return false;
+                    }
                     switch (entryKind) {
                         case 0: return stat.isFile();
                         case 1: return stat.isDirectory();
@@ -4803,8 +4813,9 @@ var ts;
                 }
             }
             function getModifiedTime(path) {
+                var _a;
                 try {
-                    return _fs.statSync(path).mtime;
+                    return (_a = statSync(path)) === null || _a === void 0 ? void 0 : _a.mtime;
                 }
                 catch (e) {
                     return undefined;
diff --git a/lib/tsserver.js b/lib/tsserver.js
index e8afc692648bb..a4f0e241cf987 100644
--- a/lib/tsserver.js
+++ b/lib/tsserver.js
@@ -94,7 +94,7 @@ var ts;
     // If changing the text in this section, be sure to test `configurePrerelease` too.
     ts.versionMajorMinor = "4.1";
     /** The version of the TypeScript compiler release */
-    ts.version = "4.1.5";
+    ts.version = "4.1.6";
     /* @internal */
     var Comparison;
     (function (Comparison) {
@@ -7022,8 +7022,8 @@ var ts;
                 },
                 getFileSize: function (path) {
                     try {
-                        var stat = _fs.statSync(path);
-                        if (stat.isFile()) {
+                        var stat = statSync(path);
+                        if (stat === null || stat === void 0 ? void 0 : stat.isFile()) {
                             return stat.size;
                         }
                     }
@@ -7069,6 +7069,15 @@ var ts;
                 }
             };
             return nodeSystem;
+            /**
+             * `throwIfNoEntry` was added so recently that it's not in the node types.
+             * This helper encapsulates the mitigating usage of `any`.
+             * See https://github.com/nodejs/node/pull/33716
+             */
+            function statSync(path) {
+                // throwIfNoEntry will be ignored by older versions of node
+                return _fs.statSync(path, { throwIfNoEntry: false });
+            }
             /**
              * Uses the builtin inspector APIs to capture a CPU profile
              * See https://nodejs.org/api/inspector.html#inspector_example_usage for details
@@ -7123,20 +7132,21 @@ var ts;
                 if (activeSession && activeSession !== "stopping") {
                     var s_1 = activeSession;
                     activeSession.post("Profiler.stop", function (err, _a) {
+                        var _b;
                         var profile = _a.profile;
                         if (!err) {
                             try {
-                                if (_fs.statSync(profilePath).isDirectory()) {
+                                if ((_b = statSync(profilePath)) === null || _b === void 0 ? void 0 : _b.isDirectory()) {
                                     profilePath = _path.join(profilePath, (new Date()).toISOString().replace(/:/g, "-") + "+P" + process.pid + ".cpuprofile");
                                 }
                             }
-                            catch (_b) {
+                            catch (_c) {
                                 // do nothing and ignore fallible fs operation
                             }
                             try {
                                 _fs.mkdirSync(_path.dirname(profilePath), { recursive: true });
                             }
-                            catch (_c) {
+                            catch (_d) {
                                 // do nothing and ignore fallible fs operation
                             }
                             _fs.writeFileSync(profilePath, JSON.stringify(cleanupPaths(profile)));
@@ -7375,7 +7385,10 @@ var ts;
                         if (typeof dirent === "string" || dirent.isSymbolicLink()) {
                             var name = ts.combinePaths(path, entry);
                             try {
-                                stat = _fs.statSync(name);
+                                stat = statSync(name);
+                                if (!stat) {
+                                    continue;
+                                }
                             }
                             catch (e) {
                                 continue;
@@ -7408,7 +7421,10 @@ var ts;
                 var originalStackTraceLimit = Error.stackTraceLimit;
                 Error.stackTraceLimit = 0;
                 try {
-                    var stat = _fs.statSync(path);
+                    var stat = statSync(path);
+                    if (!stat) {
+                        return false;
+                    }
                     switch (entryKind) {
                         case 0 /* File */: return stat.isFile();
                         case 1 /* Directory */: return stat.isDirectory();
@@ -7440,8 +7456,9 @@ var ts;
                 }
             }
             function getModifiedTime(path) {
+                var _a;
                 try {
-                    return _fs.statSync(path).mtime;
+                    return (_a = statSync(path)) === null || _a === void 0 ? void 0 : _a.mtime;
                 }
                 catch (e) {
                     return undefined;
@@ -160609,6 +160626,7 @@ var ts;
             var nextFileToCheck = 0;
             return { getModifiedTime: getModifiedTime, poll: poll, startWatchTimer: startWatchTimer, addFile: addFile, removeFile: removeFile };
             function getModifiedTime(fileName) {
+                // Caller guarantees that `fileName` exists, so there'd be no benefit from throwIfNoEntry
                 return fs.statSync(fileName).mtime;
             }
             function poll(checkedIndex) {
diff --git a/lib/tsserverlibrary.js b/lib/tsserverlibrary.js
index f1e50768d9709..f225c4ae14e25 100644
--- a/lib/tsserverlibrary.js
+++ b/lib/tsserverlibrary.js
@@ -288,7 +288,7 @@ var ts;
     // If changing the text in this section, be sure to test `configurePrerelease` too.
     ts.versionMajorMinor = "4.1";
     /** The version of the TypeScript compiler release */
-    ts.version = "4.1.5";
+    ts.version = "4.1.6";
     /* @internal */
     var Comparison;
     (function (Comparison) {
@@ -7216,8 +7216,8 @@ var ts;
                 },
                 getFileSize: function (path) {
                     try {
-                        var stat = _fs.statSync(path);
-                        if (stat.isFile()) {
+                        var stat = statSync(path);
+                        if (stat === null || stat === void 0 ? void 0 : stat.isFile()) {
                             return stat.size;
                         }
                     }
@@ -7263,6 +7263,15 @@ var ts;
                 }
             };
             return nodeSystem;
+            /**
+             * `throwIfNoEntry` was added so recently that it's not in the node types.
+             * This helper encapsulates the mitigating usage of `any`.
+             * See https://github.com/nodejs/node/pull/33716
+             */
+            function statSync(path) {
+                // throwIfNoEntry will be ignored by older versions of node
+                return _fs.statSync(path, { throwIfNoEntry: false });
+            }
             /**
              * Uses the builtin inspector APIs to capture a CPU profile
              * See https://nodejs.org/api/inspector.html#inspector_example_usage for details
@@ -7317,20 +7326,21 @@ var ts;
                 if (activeSession && activeSession !== "stopping") {
                     var s_1 = activeSession;
                     activeSession.post("Profiler.stop", function (err, _a) {
+                        var _b;
                         var profile = _a.profile;
                         if (!err) {
                             try {
-                                if (_fs.statSync(profilePath).isDirectory()) {
+                                if ((_b = statSync(profilePath)) === null || _b === void 0 ? void 0 : _b.isDirectory()) {
                                     profilePath = _path.join(profilePath, (new Date()).toISOString().replace(/:/g, "-") + "+P" + process.pid + ".cpuprofile");
                                 }
                             }
-                            catch (_b) {
+                            catch (_c) {
                                 // do nothing and ignore fallible fs operation
                             }
                             try {
                                 _fs.mkdirSync(_path.dirname(profilePath), { recursive: true });
                             }
-                            catch (_c) {
+                            catch (_d) {
                                 // do nothing and ignore fallible fs operation
                             }
                             _fs.writeFileSync(profilePath, JSON.stringify(cleanupPaths(profile)));
@@ -7569,7 +7579,10 @@ var ts;
                         if (typeof dirent === "string" || dirent.isSymbolicLink()) {
                             var name = ts.combinePaths(path, entry);
                             try {
-                                stat = _fs.statSync(name);
+                                stat = statSync(name);
+                                if (!stat) {
+                                    continue;
+                                }
                             }
                             catch (e) {
                                 continue;
@@ -7602,7 +7615,10 @@ var ts;
                 var originalStackTraceLimit = Error.stackTraceLimit;
                 Error.stackTraceLimit = 0;
                 try {
-                    var stat = _fs.statSync(path);
+                    var stat = statSync(path);
+                    if (!stat) {
+                        return false;
+                    }
                     switch (entryKind) {
                         case 0 /* File */: return stat.isFile();
                         case 1 /* Directory */: return stat.isDirectory();
@@ -7634,8 +7650,9 @@ var ts;
                 }
             }
             function getModifiedTime(path) {
+                var _a;
                 try {
-                    return _fs.statSync(path).mtime;
+                    return (_a = statSync(path)) === null || _a === void 0 ? void 0 : _a.mtime;
                 }
                 catch (e) {
                     return undefined;
diff --git a/lib/typescript.js b/lib/typescript.js
index d644aea385de1..bc97fa33f3a19 100644
--- a/lib/typescript.js
+++ b/lib/typescript.js
@@ -288,7 +288,7 @@ var ts;
     // If changing the text in this section, be sure to test `configurePrerelease` too.
     ts.versionMajorMinor = "4.1";
     /** The version of the TypeScript compiler release */
-    ts.version = "4.1.5";
+    ts.version = "4.1.6";
     /* @internal */
     var Comparison;
     (function (Comparison) {
@@ -7216,8 +7216,8 @@ var ts;
                 },
                 getFileSize: function (path) {
                     try {
-                        var stat = _fs.statSync(path);
-                        if (stat.isFile()) {
+                        var stat = statSync(path);
+                        if (stat === null || stat === void 0 ? void 0 : stat.isFile()) {
                             return stat.size;
                         }
                     }
@@ -7263,6 +7263,15 @@ var ts;
                 }
             };
             return nodeSystem;
+            /**
+             * `throwIfNoEntry` was added so recently that it's not in the node types.
+             * This helper encapsulates the mitigating usage of `any`.
+             * See https://github.com/nodejs/node/pull/33716
+             */
+            function statSync(path) {
+                // throwIfNoEntry will be ignored by older versions of node
+                return _fs.statSync(path, { throwIfNoEntry: false });
+            }
             /**
              * Uses the builtin inspector APIs to capture a CPU profile
              * See https://nodejs.org/api/inspector.html#inspector_example_usage for details
@@ -7317,20 +7326,21 @@ var ts;
                 if (activeSession && activeSession !== "stopping") {
                     var s_1 = activeSession;
                     activeSession.post("Profiler.stop", function (err, _a) {
+                        var _b;
                         var profile = _a.profile;
                         if (!err) {
                             try {
-                                if (_fs.statSync(profilePath).isDirectory()) {
+                                if ((_b = statSync(profilePath)) === null || _b === void 0 ? void 0 : _b.isDirectory()) {
                                     profilePath = _path.join(profilePath, (new Date()).toISOString().replace(/:/g, "-") + "+P" + process.pid + ".cpuprofile");
                                 }
                             }
-                            catch (_b) {
+                            catch (_c) {
                                 // do nothing and ignore fallible fs operation
                             }
                             try {
                                 _fs.mkdirSync(_path.dirname(profilePath), { recursive: true });
                             }
-                            catch (_c) {
+                            catch (_d) {
                                 // do nothing and ignore fallible fs operation
                             }
                             _fs.writeFileSync(profilePath, JSON.stringify(cleanupPaths(profile)));
@@ -7569,7 +7579,10 @@ var ts;
                         if (typeof dirent === "string" || dirent.isSymbolicLink()) {
                             var name = ts.combinePaths(path, entry);
                             try {
-                                stat = _fs.statSync(name);
+                                stat = statSync(name);
+                                if (!stat) {
+                                    continue;
+                                }
                             }
                             catch (e) {
                                 continue;
@@ -7602,7 +7615,10 @@ var ts;
                 var originalStackTraceLimit = Error.stackTraceLimit;
                 Error.stackTraceLimit = 0;
                 try {
-                    var stat = _fs.statSync(path);
+                    var stat = statSync(path);
+                    if (!stat) {
+                        return false;
+                    }
                     switch (entryKind) {
                         case 0 /* File */: return stat.isFile();
                         case 1 /* Directory */: return stat.isDirectory();
@@ -7634,8 +7650,9 @@ var ts;
                 }
             }
             function getModifiedTime(path) {
+                var _a;
                 try {
-                    return _fs.statSync(path).mtime;
+                    return (_a = statSync(path)) === null || _a === void 0 ? void 0 : _a.mtime;
                 }
                 catch (e) {
                     return undefined;
diff --git a/lib/typescriptServices.js b/lib/typescriptServices.js
index 5de94cc871fd9..c1e36c20af971 100644
--- a/lib/typescriptServices.js
+++ b/lib/typescriptServices.js
@@ -288,7 +288,7 @@ var ts;
     // If changing the text in this section, be sure to test `configurePrerelease` too.
     ts.versionMajorMinor = "4.1";
     /** The version of the TypeScript compiler release */
-    ts.version = "4.1.5";
+    ts.version = "4.1.6";
     /* @internal */
     var Comparison;
     (function (Comparison) {
@@ -7216,8 +7216,8 @@ var ts;
                 },
                 getFileSize: function (path) {
                     try {
-                        var stat = _fs.statSync(path);
-                        if (stat.isFile()) {
+                        var stat = statSync(path);
+                        if (stat === null || stat === void 0 ? void 0 : stat.isFile()) {
                             return stat.size;
                         }
                     }
@@ -7263,6 +7263,15 @@ var ts;
                 }
             };
             return nodeSystem;
+            /**
+             * `throwIfNoEntry` was added so recently that it's not in the node types.
+             * This helper encapsulates the mitigating usage of `any`.
+             * See https://github.com/nodejs/node/pull/33716
+             */
+            function statSync(path) {
+                // throwIfNoEntry will be ignored by older versions of node
+                return _fs.statSync(path, { throwIfNoEntry: false });
+            }
             /**
              * Uses the builtin inspector APIs to capture a CPU profile
              * See https://nodejs.org/api/inspector.html#inspector_example_usage for details
@@ -7317,20 +7326,21 @@ var ts;
                 if (activeSession && activeSession !== "stopping") {
                     var s_1 = activeSession;
                     activeSession.post("Profiler.stop", function (err, _a) {
+                        var _b;
                         var profile = _a.profile;
                         if (!err) {
                             try {
-                                if (_fs.statSync(profilePath).isDirectory()) {
+                                if ((_b = statSync(profilePath)) === null || _b === void 0 ? void 0 : _b.isDirectory()) {
                                     profilePath = _path.join(profilePath, (new Date()).toISOString().replace(/:/g, "-") + "+P" + process.pid + ".cpuprofile");
                                 }
                             }
-                            catch (_b) {
+                            catch (_c) {
                                 // do nothing and ignore fallible fs operation
                             }
                             try {
                                 _fs.mkdirSync(_path.dirname(profilePath), { recursive: true });
                             }
-                            catch (_c) {
+                            catch (_d) {
                                 // do nothing and ignore fallible fs operation
                             }
                             _fs.writeFileSync(profilePath, JSON.stringify(cleanupPaths(profile)));
@@ -7569,7 +7579,10 @@ var ts;
                         if (typeof dirent === "string" || dirent.isSymbolicLink()) {
                             var name = ts.combinePaths(path, entry);
                             try {
-                                stat = _fs.statSync(name);
+                                stat = statSync(name);
+                                if (!stat) {
+                                    continue;
+                                }
                             }
                             catch (e) {
                                 continue;
@@ -7602,7 +7615,10 @@ var ts;
                 var originalStackTraceLimit = Error.stackTraceLimit;
                 Error.stackTraceLimit = 0;
                 try {
-                    var stat = _fs.statSync(path);
+                    var stat = statSync(path);
+                    if (!stat) {
+                        return false;
+                    }
                     switch (entryKind) {
                         case 0 /* File */: return stat.isFile();
                         case 1 /* Directory */: return stat.isDirectory();
@@ -7634,8 +7650,9 @@ var ts;
                 }
             }
             function getModifiedTime(path) {
+                var _a;
                 try {
-                    return _fs.statSync(path).mtime;
+                    return (_a = statSync(path)) === null || _a === void 0 ? void 0 : _a.mtime;
                 }
                 catch (e) {
                     return undefined;
diff --git a/lib/typingsInstaller.js b/lib/typingsInstaller.js
index efc7337b2c7fb..5d37a4a4d476b 100644
--- a/lib/typingsInstaller.js
+++ b/lib/typingsInstaller.js
@@ -83,7 +83,7 @@ var ts;
     // If changing the text in this section, be sure to test `configurePrerelease` too.
     ts.versionMajorMinor = "4.1";
     /** The version of the TypeScript compiler release */
-    ts.version = "4.1.5";
+    ts.version = "4.1.6";
     /* @internal */
     var Comparison;
     (function (Comparison) {
@@ -7011,8 +7011,8 @@ var ts;
                 },
                 getFileSize: function (path) {
                     try {
-                        var stat = _fs.statSync(path);
-                        if (stat.isFile()) {
+                        var stat = statSync(path);
+                        if (stat === null || stat === void 0 ? void 0 : stat.isFile()) {
                             return stat.size;
                         }
                     }
@@ -7058,6 +7058,15 @@ var ts;
                 }
             };
             return nodeSystem;
+            /**
+             * `throwIfNoEntry` was added so recently that it's not in the node types.
+             * This helper encapsulates the mitigating usage of `any`.
+             * See https://github.com/nodejs/node/pull/33716
+             */
+            function statSync(path) {
+                // throwIfNoEntry will be ignored by older versions of node
+                return _fs.statSync(path, { throwIfNoEntry: false });
+            }
             /**
              * Uses the builtin inspector APIs to capture a CPU profile
              * See https://nodejs.org/api/inspector.html#inspector_example_usage for details
@@ -7112,20 +7121,21 @@ var ts;
                 if (activeSession && activeSession !== "stopping") {
                     var s_1 = activeSession;
                     activeSession.post("Profiler.stop", function (err, _a) {
+                        var _b;
                         var profile = _a.profile;
                         if (!err) {
                             try {
-                                if (_fs.statSync(profilePath).isDirectory()) {
+                                if ((_b = statSync(profilePath)) === null || _b === void 0 ? void 0 : _b.isDirectory()) {
                                     profilePath = _path.join(profilePath, (new Date()).toISOString().replace(/:/g, "-") + "+P" + process.pid + ".cpuprofile");
                                 }
                             }
-                            catch (_b) {
+                            catch (_c) {
                                 // do nothing and ignore fallible fs operation
                             }
                             try {
                                 _fs.mkdirSync(_path.dirname(profilePath), { recursive: true });
                             }
-                            catch (_c) {
+                            catch (_d) {
                                 // do nothing and ignore fallible fs operation
                             }
                             _fs.writeFileSync(profilePath, JSON.stringify(cleanupPaths(profile)));
@@ -7364,7 +7374,10 @@ var ts;
                         if (typeof dirent === "string" || dirent.isSymbolicLink()) {
                             var name = ts.combinePaths(path, entry);
                             try {
-                                stat = _fs.statSync(name);
+                                stat = statSync(name);
+                                if (!stat) {
+                                    continue;
+                                }
                             }
                             catch (e) {
                                 continue;
@@ -7397,7 +7410,10 @@ var ts;
                 var originalStackTraceLimit = Error.stackTraceLimit;
                 Error.stackTraceLimit = 0;
                 try {
-                    var stat = _fs.statSync(path);
+                    var stat = statSync(path);
+                    if (!stat) {
+                        return false;
+                    }
                     switch (entryKind) {
                         case 0 /* File */: return stat.isFile();
                         case 1 /* Directory */: return stat.isDirectory();
@@ -7429,8 +7445,9 @@ var ts;
                 }
             }
             function getModifiedTime(path) {
+                var _a;
                 try {
-                    return _fs.statSync(path).mtime;
+                    return (_a = statSync(path)) === null || _a === void 0 ? void 0 : _a.mtime;
                 }
                 catch (e) {
                     return undefined;
diff --git a/package.json b/package.json
index 7e90d946609b1..2d7aa389ea767 100644
--- a/package.json
+++ b/package.json
@@ -2,7 +2,7 @@
     "name": "typescript",
     "author": "Microsoft Corp.",
     "homepage": "https://www.typescriptlang.org/",
-    "version": "4.1.5",
+    "version": "4.1.6",
     "license": "Apache-2.0",
     "description": "TypeScript is a language for application scale JavaScript development",
     "keywords": [
diff --git a/src/compiler/corePublic.ts b/src/compiler/corePublic.ts
index c98c2aa9b4204..a87b5c1589f6c 100644
--- a/src/compiler/corePublic.ts
+++ b/src/compiler/corePublic.ts
@@ -3,7 +3,7 @@ namespace ts {
     // If changing the text in this section, be sure to test `configurePrerelease` too.
     export const versionMajorMinor = "4.1";
     /** The version of the TypeScript compiler release */
-    export const version = "4.1.5" as string;
+    export const version = "4.1.6" as string;
 
     /**
      * Type of objects whose values are all of the same type.