diff --git a/test/integration/fixtures/multiple-runs/multiple-runs-different-output-suite.fixture.js b/test/integration/fixtures/multiple-runs/multiple-runs-different-output-suite.fixture.js
new file mode 100644
index 0000000000..903f661bf9
--- /dev/null
+++ b/test/integration/fixtures/multiple-runs/multiple-runs-different-output-suite.fixture.js
@@ -0,0 +1,19 @@
+describe('Multiple runs', () => {
+
+  /**
+   * Shared state! Bad practice, but nice for this test
+   */
+  let i = 0;
+
+  it('should skip, fail and pass respectively', function () {
+    switch (i++) {
+      case 0:
+        this.skip();
+      case 1:
+        throw new Error('Expected error');
+      default:
+        // this is fine ☕
+        break;
+    }
+  });
+});
diff --git a/test/integration/fixtures/multiple-runs/multiple-runs-different-output.fixture.js b/test/integration/fixtures/multiple-runs/multiple-runs-different-output.fixture.js
new file mode 100644
index 0000000000..01951a7710
--- /dev/null
+++ b/test/integration/fixtures/multiple-runs/multiple-runs-different-output.fixture.js
@@ -0,0 +1,22 @@
+'use strict';
+const Mocha = require('../../../../lib/mocha');
+
+const mocha = new Mocha( { reporter: 'json' } );
+if(process.argv.indexOf('--no-clean-references') >= 0) {
+  mocha.cleanReferencesAfterRun(false);
+}
+if(process.argv.indexOf('--directly-dispose') >= 0){
+  mocha.dispose();
+}
+mocha.addFile(require.resolve('./multiple-runs-different-output-suite.fixture.js'));
+console.log('[');
+mocha.run(() => {
+  console.log(',');
+  mocha.run(() => {
+    console.log(',');
+    mocha.run(() => {
+      console.log(']');
+    });
+  });
+});
+
diff --git a/test/integration/fixtures/multiple-runs/start-second-run-if-previous-is-still-running-suite.fixture.js b/test/integration/fixtures/multiple-runs/start-second-run-if-previous-is-still-running-suite.fixture.js
new file mode 100644
index 0000000000..a8ecaf76e5
--- /dev/null
+++ b/test/integration/fixtures/multiple-runs/start-second-run-if-previous-is-still-running-suite.fixture.js
@@ -0,0 +1,5 @@
+describe('slow suite', () => {
+  it('should be slow', (done) => {
+    setTimeout(200, done);
+  });
+});
diff --git a/test/integration/fixtures/multiple-runs/start-second-run-if-previous-is-still-running.fixture.js b/test/integration/fixtures/multiple-runs/start-second-run-if-previous-is-still-running.fixture.js
new file mode 100644
index 0000000000..0cc4db3a92
--- /dev/null
+++ b/test/integration/fixtures/multiple-runs/start-second-run-if-previous-is-still-running.fixture.js
@@ -0,0 +1,8 @@
+'use strict';
+const Mocha = require('../../../../lib/mocha');
+
+const mocha = new Mocha( { reporter: 'json' } );
+mocha.addFile(require.resolve('./start-second-run-if-previous-is-still-running-suite.fixture.js'));
+mocha.run();
+mocha.run();
+
diff --git a/test/integration/multiple-runs.spec.js b/test/integration/multiple-runs.spec.js
new file mode 100644
index 0000000000..ccb0f3c892
--- /dev/null
+++ b/test/integration/multiple-runs.spec.js
@@ -0,0 +1,74 @@
+'use strict';
+
+var invokeNode = require('./helpers').invokeNode;
+
+describe('multiple runs', function(done) {
+  it('should should be allowed to run multiple times if cleanReferences is turned off', function(done) {
+    var path = require.resolve(
+      './fixtures/multiple-runs/multiple-runs-different-output.fixture.js'
+    );
+    invokeNode([path, '--no-clean-references'], function(err, res) {
+      expect(err, 'to be null');
+      expect(res.code, 'to be', 0);
+      var results = JSON.parse(res.output);
+      expect(results, 'to have length', 3);
+      expect(results[0].pending, 'to have length', 1);
+      expect(results[0].failures, 'to have length', 0);
+      expect(results[0].passes, 'to have length', 0);
+      expect(results[1].pending, 'to have length', 0);
+      expect(results[1].failures, 'to have length', 1);
+      expect(results[1].passes, 'to have length', 0);
+      expect(results[2].pending, 'to have length', 0);
+      expect(results[2].failures, 'to have length', 0);
+      expect(results[2].passes, 'to have length', 1);
+      done();
+    });
+  });
+
+  it('should should not be allowed if cleanReferences is true', function(done) {
+    var path = require.resolve(
+      './fixtures/multiple-runs/multiple-runs-different-output.fixture.js'
+    );
+    invokeNode(
+      [path],
+      function(err, res) {
+        expect(err, 'to be null');
+        expect(res.code, 'not to be', 0);
+        expect(res.output, 'to contain', 'ERR_MOCHA_INSTANCE_ALREADY_DISPOSED');
+        done();
+      },
+      {stdio: ['ignore', 'pipe', 'pipe']}
+    );
+  });
+
+  it('should should not be allowed if the instance is disposed', function(done) {
+    var path = require.resolve(
+      './fixtures/multiple-runs/multiple-runs-different-output.fixture.js'
+    );
+    invokeNode(
+      [path, '--directly-dispose'],
+      function(err, res) {
+        expect(err, 'to be null');
+        expect(res.code, 'not to be', 0);
+        expect(res.output, 'to contain', 'ERR_MOCHA_INSTANCE_ALREADY_DISPOSED');
+        done();
+      },
+      {stdio: ['ignore', 'pipe', 'pipe']}
+    );
+  });
+
+  it('should should not allowed to run while a previous run is in progress', function(done) {
+    var path = require.resolve(
+      './fixtures/multiple-runs/start-second-run-if-previous-is-still-running.fixture'
+    );
+    invokeNode(
+      [path],
+      function(err, res) {
+        expect(err, 'to be null');
+        expect(res.output, 'to contain', 'ERR_MOCHA_INSTANCE_ALREADY_RUNNING');
+        done();
+      },
+      {stdio: ['ignore', 'pipe', 'pipe']}
+    );
+  });
+});