diff --git a/BUILDING.md b/BUILDING.md
index 520d9b3d521538..99b2014c19b9ca 100644
--- a/BUILDING.md
+++ b/BUILDING.md
@@ -235,7 +235,7 @@ The Node.js project supports Python >= 3 for building and testing.
 
 * `gcc` and `g++` >= 8.3 or newer, or
 * GNU Make 3.81 or newer
-* Python 3.6, 3.7, 3.8, or 3.9 (see note above)
+* Python 3.6, 3.7, 3.8, 3.9, or 3.10 (see note above)
 
 Installation via Linux package manager can be achieved with:
 
@@ -250,7 +250,7 @@ FreeBSD and OpenBSD users may also need to install `libexecinfo`.
 #### macOS prerequisites
 
 * Xcode Command Line Tools >= 11 for macOS
-* Python 3.6, 3.7, 3.8, or 3.9 (see note above)
+* Python 3.6, 3.7, 3.8, 3.9, or 3.10 (see note above)
 
 macOS users can install the `Xcode Command Line Tools` by running
 `xcode-select --install`. Alternatively, if you already have the full Xcode
diff --git a/configure b/configure
index baf4b513da881b..6ef2da2e631e6e 100755
--- a/configure
+++ b/configure
@@ -4,6 +4,7 @@
 # Note that the mix of single and double quotes is intentional,
 # as is the fact that the ] goes on a new line.
 _=[ 'exec' '/bin/sh' '-c' '''
+command -v python3.10 >/dev/null && exec python3.10 "$0" "$@"
 command -v python3.9 >/dev/null && exec python3.9 "$0" "$@"
 command -v python3.8 >/dev/null && exec python3.8 "$0" "$@"
 command -v python3.7 >/dev/null && exec python3.7 "$0" "$@"
@@ -21,7 +22,7 @@ except ImportError:
   from distutils.spawn import find_executable as which
 
 print('Node.js configure: Found Python {}.{}.{}...'.format(*sys.version_info))
-acceptable_pythons = ((3, 9), (3, 8), (3, 7), (3, 6))
+acceptable_pythons = ((3, 10), (3, 9), (3, 8), (3, 7), (3, 6))
 if sys.version_info[:2] in acceptable_pythons:
   import configure
 else: