diff --git a/src/async_wrap-inl.h b/src/async_wrap-inl.h
index 08f305da8a3192..30b29c83e0c90c 100644
--- a/src/async_wrap-inl.h
+++ b/src/async_wrap-inl.h
@@ -80,6 +80,12 @@ inline v8::MaybeLocal<v8::Value> AsyncWrap::MakeCallback(
   return MakeCallback(cb_v.As<v8::Function>(), argc, argv);
 }
 
+// static
+inline v8::Local<v8::FunctionTemplate> AsyncWrap::GetConstructorTemplate(
+    Environment* env) {
+  return GetConstructorTemplate(env->isolate_data());
+}
+
 }  // namespace node
 
 #endif  // defined(NODE_WANT_INTERNALS) && NODE_WANT_INTERNALS
diff --git a/src/async_wrap.cc b/src/async_wrap.cc
index c51d4aaabba285..ff550fdc1de5d0 100644
--- a/src/async_wrap.cc
+++ b/src/async_wrap.cc
@@ -334,18 +334,20 @@ void AsyncWrap::SetCallbackTrampoline(const FunctionCallbackInfo<Value>& args) {
   }
 }
 
-Local<FunctionTemplate> AsyncWrap::GetConstructorTemplate(Environment* env) {
-  Local<FunctionTemplate> tmpl = env->async_wrap_ctor_template();
+Local<FunctionTemplate> AsyncWrap::GetConstructorTemplate(
+    IsolateData* isolate_data) {
+  Local<FunctionTemplate> tmpl = isolate_data->async_wrap_ctor_template();
   if (tmpl.IsEmpty()) {
-    Isolate* isolate = env->isolate();
+    Isolate* isolate = isolate_data->isolate();
     tmpl = NewFunctionTemplate(isolate, nullptr);
-    tmpl->SetClassName(FIXED_ONE_BYTE_STRING(env->isolate(), "AsyncWrap"));
-    tmpl->Inherit(BaseObject::GetConstructorTemplate(env));
+    tmpl->SetClassName(
+        FIXED_ONE_BYTE_STRING(isolate_data->isolate(), "AsyncWrap"));
+    tmpl->Inherit(BaseObject::GetConstructorTemplate(isolate_data));
     SetProtoMethod(isolate, tmpl, "getAsyncId", AsyncWrap::GetAsyncId);
     SetProtoMethod(isolate, tmpl, "asyncReset", AsyncWrap::AsyncReset);
     SetProtoMethod(
         isolate, tmpl, "getProviderType", AsyncWrap::GetProviderType);
-    env->set_async_wrap_ctor_template(tmpl);
+    isolate_data->set_async_wrap_ctor_template(tmpl);
   }
   return tmpl;
 }
diff --git a/src/async_wrap.h b/src/async_wrap.h
index f7ed25f9eea318..5ccf3f86bac532 100644
--- a/src/async_wrap.h
+++ b/src/async_wrap.h
@@ -138,6 +138,8 @@ class AsyncWrap : public BaseObject {
   static constexpr double kInvalidAsyncId = -1;
 
   static v8::Local<v8::FunctionTemplate> GetConstructorTemplate(
+      IsolateData* isolate_data);
+  inline static v8::Local<v8::FunctionTemplate> GetConstructorTemplate(
       Environment* env);
 
   static void RegisterExternalReferences(ExternalReferenceRegistry* registry);
diff --git a/src/inspector_js_api.cc b/src/inspector_js_api.cc
index ed193688ee1da9..3595536c785ed7 100644
--- a/src/inspector_js_api.cc
+++ b/src/inspector_js_api.cc
@@ -1,3 +1,4 @@
+#include "async_wrap-inl.h"
 #include "base_object-inl.h"
 #include "inspector_agent.h"
 #include "inspector_io.h"
diff --git a/src/node_binding.h b/src/node_binding.h
index b403bf26b81d91..c140297f5ca936 100644
--- a/src/node_binding.h
+++ b/src/node_binding.h
@@ -24,7 +24,9 @@ static_assert(static_cast<int>(NM_F_LINKED) ==
               static_cast<int>(node::ModuleFlags::kLinked),
               "NM_F_LINKED != node::ModuleFlags::kLinked");
 
-#define NODE_BINDINGS_WITH_PER_ISOLATE_INIT(V) V(builtins)
+#define NODE_BINDINGS_WITH_PER_ISOLATE_INIT(V)                                 \
+  V(builtins)                                                                  \
+  V(worker)
 
 #define NODE_BINDING_CONTEXT_AWARE_CPP(modname, regfunc, priv, flags)          \
   static node::node_module _module = {                                         \
diff --git a/src/node_worker.cc b/src/node_worker.cc
index 5f7d807b1dac8f..b84a39cce330d7 100644
--- a/src/node_worker.cc
+++ b/src/node_worker.cc
@@ -34,6 +34,7 @@ using v8::MaybeLocal;
 using v8::Null;
 using v8::Number;
 using v8::Object;
+using v8::ObjectTemplate;
 using v8::ResourceConstraints;
 using v8::SealHandleScope;
 using v8::String;
@@ -876,19 +877,17 @@ void GetEnvMessagePort(const FunctionCallbackInfo<Value>& args) {
   }
 }
 
-void InitWorker(Local<Object> target,
-                Local<Value> unused,
-                Local<Context> context,
-                void* priv) {
-  Environment* env = Environment::GetCurrent(context);
-  Isolate* isolate = env->isolate();
+void CreateWorkerPerIsolateProperties(IsolateData* isolate_data,
+                                      Local<FunctionTemplate> target) {
+  Isolate* isolate = isolate_data->isolate();
+  Local<ObjectTemplate> proto = target->PrototypeTemplate();
 
   {
     Local<FunctionTemplate> w = NewFunctionTemplate(isolate, Worker::New);
 
     w->InstanceTemplate()->SetInternalFieldCount(
         Worker::kInternalFieldCount);
-    w->Inherit(AsyncWrap::GetConstructorTemplate(env));
+    w->Inherit(AsyncWrap::GetConstructorTemplate(isolate_data));
 
     SetProtoMethod(isolate, w, "startThread", Worker::StartThread);
     SetProtoMethod(isolate, w, "stopThread", Worker::StopThread);
@@ -900,7 +899,7 @@ void InitWorker(Local<Object> target,
     SetProtoMethod(isolate, w, "loopIdleTime", Worker::LoopIdleTime);
     SetProtoMethod(isolate, w, "loopStartTime", Worker::LoopStartTime);
 
-    SetConstructorFunction(context, target, "Worker", w);
+    SetConstructorFunction(isolate, proto, "Worker", w);
   }
 
   {
@@ -908,15 +907,24 @@ void InitWorker(Local<Object> target,
 
     wst->InstanceTemplate()->SetInternalFieldCount(
         WorkerHeapSnapshotTaker::kInternalFieldCount);
-    wst->Inherit(AsyncWrap::GetConstructorTemplate(env));
+    wst->Inherit(AsyncWrap::GetConstructorTemplate(isolate_data));
 
     Local<String> wst_string =
         FIXED_ONE_BYTE_STRING(isolate, "WorkerHeapSnapshotTaker");
     wst->SetClassName(wst_string);
-    env->set_worker_heap_snapshot_taker_template(wst->InstanceTemplate());
+    isolate_data->set_worker_heap_snapshot_taker_template(
+        wst->InstanceTemplate());
   }
 
-  SetMethod(context, target, "getEnvMessagePort", GetEnvMessagePort);
+  SetMethod(isolate, proto, "getEnvMessagePort", GetEnvMessagePort);
+}
+
+void CreateWorkerPerContextProperties(Local<Object> target,
+                                      Local<Value> unused,
+                                      Local<Context> context,
+                                      void* priv) {
+  Environment* env = Environment::GetCurrent(context);
+  Isolate* isolate = env->isolate();
 
   target
       ->Set(env->context(),
@@ -969,6 +977,9 @@ void RegisterExternalReferences(ExternalReferenceRegistry* registry) {
 }  // namespace worker
 }  // namespace node
 
-NODE_BINDING_CONTEXT_AWARE_INTERNAL(worker, node::worker::InitWorker)
+NODE_BINDING_CONTEXT_AWARE_INTERNAL(
+    worker, node::worker::CreateWorkerPerContextProperties)
+NODE_BINDING_PER_ISOLATE_INIT(worker,
+                              node::worker::CreateWorkerPerIsolateProperties)
 NODE_BINDING_EXTERNAL_REFERENCE(worker,
                                 node::worker::RegisterExternalReferences)
diff --git a/src/util.cc b/src/util.cc
index 762bf393e8e086..78c6123c37a12a 100644
--- a/src/util.cc
+++ b/src/util.cc
@@ -56,9 +56,13 @@ static std::atomic_int seq = {0};  // Sequence number for diagnostic filenames.
 namespace node {
 
 using v8::ArrayBufferView;
+using v8::Context;
+using v8::FunctionTemplate;
 using v8::Isolate;
 using v8::Local;
+using v8::Object;
 using v8::String;
+using v8::Template;
 using v8::Value;
 
 template <typename T>
@@ -482,14 +486,33 @@ void SetConstructorFunction(Local<v8::Context> context,
       context, that, OneByteString(isolate, name), tmpl, flag);
 }
 
-void SetConstructorFunction(Local<v8::Context> context,
-                            Local<v8::Object> that,
-                            Local<v8::String> name,
-                            Local<v8::FunctionTemplate> tmpl,
+void SetConstructorFunction(Local<Context> context,
+                            Local<Object> that,
+                            Local<String> name,
+                            Local<FunctionTemplate> tmpl,
                             SetConstructorFunctionFlag flag) {
   if (LIKELY(flag == SetConstructorFunctionFlag::SET_CLASS_NAME))
     tmpl->SetClassName(name);
   that->Set(context, name, tmpl->GetFunction(context).ToLocalChecked()).Check();
 }
 
+void SetConstructorFunction(Isolate* isolate,
+                            Local<Template> that,
+                            const char* name,
+                            Local<FunctionTemplate> tmpl,
+                            SetConstructorFunctionFlag flag) {
+  SetConstructorFunction(
+      isolate, that, OneByteString(isolate, name), tmpl, flag);
+}
+
+void SetConstructorFunction(Isolate* isolate,
+                            Local<Template> that,
+                            Local<String> name,
+                            Local<FunctionTemplate> tmpl,
+                            SetConstructorFunctionFlag flag) {
+  if (LIKELY(flag == SetConstructorFunctionFlag::SET_CLASS_NAME))
+    tmpl->SetClassName(name);
+  that->Set(name, tmpl);
+}
+
 }  // namespace node
diff --git a/src/util.h b/src/util.h
index fa4b28745dbe6c..d50fea060e2b83 100644
--- a/src/util.h
+++ b/src/util.h
@@ -932,6 +932,20 @@ void SetConstructorFunction(v8::Local<v8::Context> context,
                             SetConstructorFunctionFlag flag =
                                 SetConstructorFunctionFlag::SET_CLASS_NAME);
 
+void SetConstructorFunction(v8::Isolate* isolate,
+                            v8::Local<v8::Template> that,
+                            const char* name,
+                            v8::Local<v8::FunctionTemplate> tmpl,
+                            SetConstructorFunctionFlag flag =
+                                SetConstructorFunctionFlag::SET_CLASS_NAME);
+
+void SetConstructorFunction(v8::Isolate* isolate,
+                            v8::Local<v8::Template> that,
+                            v8::Local<v8::String> name,
+                            v8::Local<v8::FunctionTemplate> tmpl,
+                            SetConstructorFunctionFlag flag =
+                                SetConstructorFunctionFlag::SET_CLASS_NAME);
+
 }  // namespace node
 
 #endif  // defined(NODE_WANT_INTERNALS) && NODE_WANT_INTERNALS