diff --git a/doc/api/fs.md b/doc/api/fs.md
index 8c12ce0bdbd9ca..afb65b707244a5 100644
--- a/doc/api/fs.md
+++ b/doc/api/fs.md
@@ -795,6 +795,10 @@ rejection only when `recursive` is false.
 ### `fsPromises.mkdtemp(prefix[, options])`
 <!-- YAML
 added: v10.0.0
+changes:
+  - version: REPLACEME
+    pr-url: https://github.com/nodejs/node/pull/39028
+    description: The `prefix` parameter now accepts an empty string.
 -->
 
 * `prefix` {string}
@@ -2533,6 +2537,9 @@ See the POSIX mkdir(2) documentation for more details.
 <!-- YAML
 added: v5.10.0
 changes:
+  - version: REPLACEME
+    pr-url: https://github.com/nodejs/node/pull/39028
+    description: The `prefix` parameter now accepts an empty string.
   - version: v10.0.0
     pr-url: https://github.com/nodejs/node/pull/12562
     description: The `callback` parameter is no longer optional. Not passing
@@ -4434,6 +4441,10 @@ See the POSIX mkdir(2) documentation for more details.
 ### `fs.mkdtempSync(prefix[, options])`
 <!-- YAML
 added: v5.10.0
+changes:
+  - version: REPLACEME
+    pr-url: https://github.com/nodejs/node/pull/39028
+    description: The `prefix` parameter now accepts an empty string.
 -->
 
 * `prefix` {string}
diff --git a/lib/fs.js b/lib/fs.js
index 836550e7c283cb..2ffb5710c09060 100644
--- a/lib/fs.js
+++ b/lib/fs.js
@@ -119,7 +119,8 @@ const {
   parseFileMode,
   validateBuffer,
   validateInteger,
-  validateInt32
+  validateInt32,
+  validateString,
 } = require('internal/validators');
 
 let truncateWarn = true;
@@ -1999,9 +2000,8 @@ realpath.native = (path, options, callback) => {
 function mkdtemp(prefix, options, callback) {
   callback = makeCallback(typeof options === 'function' ? options : callback);
   options = getOptions(options, {});
-  if (!prefix || typeof prefix !== 'string') {
-    throw new ERR_INVALID_ARG_TYPE('prefix', 'string', prefix);
-  }
+
+  validateString(prefix, 'prefix');
   nullCheck(prefix, 'prefix');
   warnOnNonPortableTemplate(prefix);
   const req = new FSReqCallback();
@@ -2012,9 +2012,8 @@ function mkdtemp(prefix, options, callback) {
 
 function mkdtempSync(prefix, options) {
   options = getOptions(options, {});
-  if (!prefix || typeof prefix !== 'string') {
-    throw new ERR_INVALID_ARG_TYPE('prefix', 'string', prefix);
-  }
+
+  validateString(prefix, 'prefix');
   nullCheck(prefix, 'prefix');
   warnOnNonPortableTemplate(prefix);
   const path = `${prefix}XXXXXX`;
diff --git a/lib/internal/fs/promises.js b/lib/internal/fs/promises.js
index b9b705caec2899..8405b5d0f5b3da 100644
--- a/lib/internal/fs/promises.js
+++ b/lib/internal/fs/promises.js
@@ -66,6 +66,7 @@ const {
   validateAbortSignal,
   validateBuffer,
   validateInteger,
+  validateString,
 } = require('internal/validators');
 const pathModule = require('path');
 const { promisify } = require('internal/util');
@@ -671,9 +672,8 @@ async function realpath(path, options) {
 
 async function mkdtemp(prefix, options) {
   options = getOptions(options, {});
-  if (!prefix || typeof prefix !== 'string') {
-    throw new ERR_INVALID_ARG_TYPE('prefix', 'string', prefix);
-  }
+
+  validateString(prefix, 'prefix');
   nullCheck(prefix);
   warnOnNonPortableTemplate(prefix);
   return binding.mkdtemp(`${prefix}XXXXXX`, options.encoding, kUsePromises);
diff --git a/test/parallel/test-fs-mkdtemp-prefix-check.js b/test/parallel/test-fs-mkdtemp-prefix-check.js
index 1d9d88232a067e..33a06914a46e10 100644
--- a/test/parallel/test-fs-mkdtemp-prefix-check.js
+++ b/test/parallel/test-fs-mkdtemp-prefix-check.js
@@ -3,7 +3,7 @@ const common = require('../common');
 const assert = require('assert');
 const fs = require('fs');
 
-const prefixValues = [undefined, null, 0, true, false, 1, ''];
+const prefixValues = [undefined, null, 0, true, false, 1];
 
 function fail(value) {
   assert.throws(