diff --git a/src/api/environment.cc b/src/api/environment.cc
index fdfd257aec12f5..a18c21fa797422 100644
--- a/src/api/environment.cc
+++ b/src/api/environment.cc
@@ -239,9 +239,11 @@ void SetIsolateMiscHandlers(v8::Isolate* isolate, const IsolateSettings& s) {
     s.allow_wasm_code_generation_callback : AllowWasmCodeGenerationCallback;
   isolate->SetAllowWasmCodeGenerationCallback(allow_wasm_codegen_cb);
 
-  auto* promise_reject_cb = s.promise_reject_callback ?
-    s.promise_reject_callback : task_queue::PromiseRejectCallback;
-  isolate->SetPromiseRejectCallback(promise_reject_cb);
+  if ((s.flags & SHOULD_NOT_SET_PROMISE_REJECTION_CALLBACK) == 0) {
+    auto* promise_reject_cb = s.promise_reject_callback ?
+      s.promise_reject_callback : task_queue::PromiseRejectCallback;
+    isolate->SetPromiseRejectCallback(promise_reject_cb);
+  }
 
   if (s.flags & DETAILED_SOURCE_POSITIONS_FOR_PROFILING)
     v8::CpuProfiler::UseDetailedSourcePositionsForProfiling(isolate);
diff --git a/src/node.h b/src/node.h
index 25f9f9b873cee3..71273d6db9c6ed 100644
--- a/src/node.h
+++ b/src/node.h
@@ -333,7 +333,8 @@ class NODE_EXTERN MultiIsolatePlatform : public v8::Platform {
 
 enum IsolateSettingsFlags {
   MESSAGE_LISTENER_WITH_ERROR_LEVEL = 1 << 0,
-  DETAILED_SOURCE_POSITIONS_FOR_PROFILING = 1 << 1
+  DETAILED_SOURCE_POSITIONS_FOR_PROFILING = 1 << 1,
+  SHOULD_NOT_SET_PROMISE_REJECTION_CALLBACK = 1 << 2
 };
 
 struct IsolateSettings {