diff --git a/.github/workflows/build-tarball.yml b/.github/workflows/build-tarball.yml
index cf6e2ce3673149..ed412723588d15 100644
--- a/.github/workflows/build-tarball.yml
+++ b/.github/workflows/build-tarball.yml
@@ -16,7 +16,7 @@ env:
 jobs:
   build-tarball:
     env:
-      PYTHON_VERSION: 3.9
+      PYTHON_VERSION: '3.10'
     runs-on: ubuntu-latest
     steps:
       - uses: actions/checkout@v2
@@ -41,7 +41,7 @@ jobs:
           path: tarballs
   test-tarball-linux:
     env:
-      PYTHON_VERSION: 3.9
+      PYTHON_VERSION: '3.10'
     needs: build-tarball
     runs-on: ubuntu-latest
     steps:
diff --git a/.github/workflows/build-windows.yml b/.github/workflows/build-windows.yml
index d04028cab029d8..e30274c47ad033 100644
--- a/.github/workflows/build-windows.yml
+++ b/.github/workflows/build-windows.yml
@@ -12,7 +12,7 @@ on:
       - v[0-9]+.x
 
 env:
-  PYTHON_VERSION: 3.9
+  PYTHON_VERSION: '3.10'
   FLAKY_TESTS: dontcare
 
 jobs:
diff --git a/.github/workflows/linters.yml b/.github/workflows/linters.yml
index 38168318ee7cc3..0264edaa940738 100644
--- a/.github/workflows/linters.yml
+++ b/.github/workflows/linters.yml
@@ -11,7 +11,7 @@ on:
       - v[0-9]+.x
 
 env:
-  PYTHON_VERSION: 3.9
+  PYTHON_VERSION: '3.10'
   NODE_VERSION: lts/*
 
 jobs:
diff --git a/.github/workflows/test-asan.yml b/.github/workflows/test-asan.yml
index 852b205d1b7e70..8958610ffeecde 100644
--- a/.github/workflows/test-asan.yml
+++ b/.github/workflows/test-asan.yml
@@ -18,7 +18,7 @@ on:
       - 'doc/**'
 
 env:
-  PYTHON_VERSION: 3.9
+  PYTHON_VERSION: '3.10'
   FLAKY_TESTS: dontcare
 
 jobs:
diff --git a/.github/workflows/test-linux.yml b/.github/workflows/test-linux.yml
index c730803e0c342a..b9ca56a4613ca5 100644
--- a/.github/workflows/test-linux.yml
+++ b/.github/workflows/test-linux.yml
@@ -12,7 +12,7 @@ on:
       - v[0-9]+.x
 
 env:
-  PYTHON_VERSION: 3.9
+  PYTHON_VERSION: '3.10'
   FLAKY_TESTS: dontcare
 
 jobs:
diff --git a/.github/workflows/test-macos.yml b/.github/workflows/test-macos.yml
index f2745218bce2c5..1461feb96f4d3b 100644
--- a/.github/workflows/test-macos.yml
+++ b/.github/workflows/test-macos.yml
@@ -18,7 +18,7 @@ on:
       - 'doc/**'
 
 env:
-  PYTHON_VERSION: 3.9
+  PYTHON_VERSION: '3.10'
   FLAKY_TESTS: dontcare
 
 jobs:
diff --git a/BUILDING.md b/BUILDING.md
index 3e5f17410b0583..5d2459eb76548f 100644
--- a/BUILDING.md
+++ b/BUILDING.md
@@ -239,7 +239,7 @@ test with Python 3.
 * GNU Make 3.81 or newer
 * Python (see note above)
   * Python 2.7
-  * Python 3.5, 3.6, 3.7, or 3.8
+  * Python 3.5, 3.6, 3.7, 3.8, 3.9 or 3.10 (see note above)
 
 Installation via Linux package manager can be achieved with:
 
@@ -256,7 +256,7 @@ FreeBSD and OpenBSD users may also need to install `libexecinfo`.
 * Xcode Command Line Tools >= 10 for macOS
 * Python (see note above)
   * Python 2.7
-  * Python 3.5, 3.6, 3.7, or 3.8
+  * Python 3.6, 3.7, 3.8, 3.9, or 3.10 (see note above)
 
 macOS users can install the `Xcode Command Line Tools` by running
 `xcode-select --install`. Alternatively, if you already have the full Xcode
diff --git a/configure b/configure
index 4fec68abf979e1..debd3cc3d452d0 100755
--- a/configure
+++ b/configure
@@ -5,6 +5,7 @@
 # as is the fact that the ] goes on a new line.
 _=[ 'exec' '/bin/sh' '-c' '''
 test ${FORCE_PYTHON2} && exec python2 "$0" "$@"  # workaround for gclient
+command -v python3.10 >/dev/null && exec python3.10 "$0" "$@"
 command -v python3.9 >/dev/null && exec python3.9 "$0" "$@"
 command -v python3.8 >/dev/null && exec python3.8 "$0" "$@"
 command -v python3.7 >/dev/null && exec python3.7 "$0" "$@"
@@ -24,7 +25,7 @@ except ImportError:
   from distutils.spawn import find_executable as which
 
 print('Node.js configure: Found Python {0}.{1}.{2}...'.format(*sys.version_info))
-acceptable_pythons = ((3, 9), (3, 8), (3, 7), (3, 6), (3, 5), (2, 7))
+acceptable_pythons = ((3,10), (3, 9), (3, 8), (3, 7), (3, 6), (3, 5), (2, 7))
 if sys.version_info[:2] in acceptable_pythons:
   import configure
 else: