diff --git a/CHANGELOG.md b/CHANGELOG.md
index ddc987b34c1..0b3f8e9d74a 100644
--- a/CHANGELOG.md
+++ b/CHANGELOG.md
@@ -8,6 +8,8 @@ This project adheres to [Semantic Versioning](https://semver.org/spec/v2.0.0.htm
 
 ## [Unreleased]
 
+## [1.6.1] - 2022-03-28
+
 ### Fixed
 
 - The `go.opentelemetry.io/otel/schema/*` packages now use the correct schema URL for their `SchemaURL` constant.
@@ -16,7 +18,7 @@ This project adheres to [Semantic Versioning](https://semver.org/spec/v2.0.0.htm
 ### Security
 
 - Upgrade `go.opentelemetry.io/proto/otlp` from `v0.12.0` to `v0.12.1`.
-  This includes an indirect upgrade of `github.com/grpc-ecosystem/grpc-gateway` which resolves [a vulnerability](https://nvd.nist.gov/vuln/detail/CVE-2019-11254) from `gopkg.in/yaml.v2` in version `v2.2.3`. (#2724, #TBD)
+  This includes an indirect upgrade of `github.com/grpc-ecosystem/grpc-gateway` which resolves [a vulnerability](https://nvd.nist.gov/vuln/detail/CVE-2019-11254) from `gopkg.in/yaml.v2` in version `v2.2.3`. (#2724, #2728)
 
 ## [1.6.0/0.28.0] - 2022-03-23
 
@@ -1778,7 +1780,8 @@ It contains api and sdk for trace and meter.
 - CircleCI build CI manifest files.
 - CODEOWNERS file to track owners of this project.
 
-[Unreleased]: https://github.com/open-telemetry/opentelemetry-go/compare/v1.6.0...HEAD
+[Unreleased]: https://github.com/open-telemetry/opentelemetry-go/compare/v1.6.1...HEAD
+[1.6.1]: https://github.com/open-telemetry/opentelemetry-go/releases/tag/v1.6.1
 [1.6.0/0.28.0]: https://github.com/open-telemetry/opentelemetry-go/releases/tag/v1.6.0
 [1.5.0]: https://github.com/open-telemetry/opentelemetry-go/releases/tag/v1.5.0
 [1.4.1]: https://github.com/open-telemetry/opentelemetry-go/releases/tag/v1.4.1
diff --git a/bridge/opencensus/go.mod b/bridge/opencensus/go.mod
index a63b24784df..a48d8bbc64d 100644
--- a/bridge/opencensus/go.mod
+++ b/bridge/opencensus/go.mod
@@ -4,11 +4,11 @@ go 1.16
 
 require (
 	go.opencensus.io v0.22.6-0.20201102222123-380f4078db9f
-	go.opentelemetry.io/otel v1.6.0
+	go.opentelemetry.io/otel v1.6.1
 	go.opentelemetry.io/otel/metric v0.28.0
-	go.opentelemetry.io/otel/sdk v1.6.0
+	go.opentelemetry.io/otel/sdk v1.6.1
 	go.opentelemetry.io/otel/sdk/metric v0.28.0
-	go.opentelemetry.io/otel/trace v1.6.0
+	go.opentelemetry.io/otel/trace v1.6.1
 )
 
 replace go.opentelemetry.io/otel => ../..
diff --git a/bridge/opencensus/test/go.mod b/bridge/opencensus/test/go.mod
index 3b180bdeb36..3e7bb8996ad 100644
--- a/bridge/opencensus/test/go.mod
+++ b/bridge/opencensus/test/go.mod
@@ -4,10 +4,10 @@ go 1.16
 
 require (
 	go.opencensus.io v0.23.0
-	go.opentelemetry.io/otel v1.6.0
+	go.opentelemetry.io/otel v1.6.1
 	go.opentelemetry.io/otel/bridge/opencensus v0.28.0
-	go.opentelemetry.io/otel/sdk v1.6.0
-	go.opentelemetry.io/otel/trace v1.6.0
+	go.opentelemetry.io/otel/sdk v1.6.1
+	go.opentelemetry.io/otel/trace v1.6.1
 )
 
 replace go.opentelemetry.io/otel => ../../..
diff --git a/bridge/opentracing/go.mod b/bridge/opentracing/go.mod
index be4871754ef..d260a60e33b 100644
--- a/bridge/opentracing/go.mod
+++ b/bridge/opentracing/go.mod
@@ -6,8 +6,8 @@ replace go.opentelemetry.io/otel => ../..
 
 require (
 	github.com/opentracing/opentracing-go v1.2.0
-	go.opentelemetry.io/otel v1.6.0
-	go.opentelemetry.io/otel/trace v1.6.0
+	go.opentelemetry.io/otel v1.6.1
+	go.opentelemetry.io/otel/trace v1.6.1
 )
 
 replace go.opentelemetry.io/otel/bridge/opencensus => ../opencensus
diff --git a/example/fib/go.mod b/example/fib/go.mod
index 617b6a5bb75..4f1411a9891 100644
--- a/example/fib/go.mod
+++ b/example/fib/go.mod
@@ -3,10 +3,10 @@ module go.opentelemetry.io/otel/example/fib
 go 1.16
 
 require (
-	go.opentelemetry.io/otel v1.6.0
-	go.opentelemetry.io/otel/exporters/stdout/stdouttrace v1.6.0
-	go.opentelemetry.io/otel/sdk v1.6.0
-	go.opentelemetry.io/otel/trace v1.6.0
+	go.opentelemetry.io/otel v1.6.1
+	go.opentelemetry.io/otel/exporters/stdout/stdouttrace v1.6.1
+	go.opentelemetry.io/otel/sdk v1.6.1
+	go.opentelemetry.io/otel/trace v1.6.1
 )
 
 replace go.opentelemetry.io/otel => ../..
diff --git a/example/jaeger/go.mod b/example/jaeger/go.mod
index 7a77c37cdbd..120eb41e62e 100644
--- a/example/jaeger/go.mod
+++ b/example/jaeger/go.mod
@@ -9,9 +9,9 @@ replace (
 )
 
 require (
-	go.opentelemetry.io/otel v1.6.0
-	go.opentelemetry.io/otel/exporters/jaeger v1.6.0
-	go.opentelemetry.io/otel/sdk v1.6.0
+	go.opentelemetry.io/otel v1.6.1
+	go.opentelemetry.io/otel/exporters/jaeger v1.6.1
+	go.opentelemetry.io/otel/sdk v1.6.1
 )
 
 replace go.opentelemetry.io/otel/bridge/opencensus => ../../bridge/opencensus
diff --git a/example/namedtracer/go.mod b/example/namedtracer/go.mod
index eb713699d54..930de80aa2d 100644
--- a/example/namedtracer/go.mod
+++ b/example/namedtracer/go.mod
@@ -9,10 +9,10 @@ replace (
 
 require (
 	github.com/go-logr/stdr v1.2.2
-	go.opentelemetry.io/otel v1.6.0
-	go.opentelemetry.io/otel/exporters/stdout/stdouttrace v1.6.0
-	go.opentelemetry.io/otel/sdk v1.6.0
-	go.opentelemetry.io/otel/trace v1.6.0
+	go.opentelemetry.io/otel v1.6.1
+	go.opentelemetry.io/otel/exporters/stdout/stdouttrace v1.6.1
+	go.opentelemetry.io/otel/sdk v1.6.1
+	go.opentelemetry.io/otel/trace v1.6.1
 )
 
 replace go.opentelemetry.io/otel/bridge/opencensus => ../../bridge/opencensus
diff --git a/example/opencensus/go.mod b/example/opencensus/go.mod
index 586843102ca..5a45f14473f 100644
--- a/example/opencensus/go.mod
+++ b/example/opencensus/go.mod
@@ -10,11 +10,11 @@ replace (
 
 require (
 	go.opencensus.io v0.22.6-0.20201102222123-380f4078db9f
-	go.opentelemetry.io/otel v1.6.0
+	go.opentelemetry.io/otel v1.6.1
 	go.opentelemetry.io/otel/bridge/opencensus v0.28.0
 	go.opentelemetry.io/otel/exporters/stdout/stdoutmetric v0.28.0
-	go.opentelemetry.io/otel/exporters/stdout/stdouttrace v1.6.0
-	go.opentelemetry.io/otel/sdk v1.6.0
+	go.opentelemetry.io/otel/exporters/stdout/stdouttrace v1.6.1
+	go.opentelemetry.io/otel/sdk v1.6.1
 	go.opentelemetry.io/otel/sdk/metric v0.28.0
 )
 
diff --git a/example/otel-collector/go.mod b/example/otel-collector/go.mod
index 957a5efff34..e6d9097d333 100644
--- a/example/otel-collector/go.mod
+++ b/example/otel-collector/go.mod
@@ -8,10 +8,10 @@ replace (
 )
 
 require (
-	go.opentelemetry.io/otel v1.6.0
-	go.opentelemetry.io/otel/exporters/otlp/otlptrace/otlptracegrpc v1.6.0
-	go.opentelemetry.io/otel/sdk v1.6.0
-	go.opentelemetry.io/otel/trace v1.6.0
+	go.opentelemetry.io/otel v1.6.1
+	go.opentelemetry.io/otel/exporters/otlp/otlptrace/otlptracegrpc v1.6.1
+	go.opentelemetry.io/otel/sdk v1.6.1
+	go.opentelemetry.io/otel/trace v1.6.1
 	google.golang.org/grpc v1.45.0
 )
 
diff --git a/example/passthrough/go.mod b/example/passthrough/go.mod
index ec53ef984e9..ba53122bfb3 100644
--- a/example/passthrough/go.mod
+++ b/example/passthrough/go.mod
@@ -3,10 +3,10 @@ module go.opentelemetry.io/otel/example/passthrough
 go 1.16
 
 require (
-	go.opentelemetry.io/otel v1.6.0
-	go.opentelemetry.io/otel/exporters/stdout/stdouttrace v1.6.0
-	go.opentelemetry.io/otel/sdk v1.6.0
-	go.opentelemetry.io/otel/trace v1.6.0
+	go.opentelemetry.io/otel v1.6.1
+	go.opentelemetry.io/otel/exporters/stdout/stdouttrace v1.6.1
+	go.opentelemetry.io/otel/sdk v1.6.1
+	go.opentelemetry.io/otel/trace v1.6.1
 )
 
 replace (
diff --git a/example/prometheus/go.mod b/example/prometheus/go.mod
index d8200474d63..65a3ab932df 100644
--- a/example/prometheus/go.mod
+++ b/example/prometheus/go.mod
@@ -9,7 +9,7 @@ replace (
 )
 
 require (
-	go.opentelemetry.io/otel v1.6.0
+	go.opentelemetry.io/otel v1.6.1
 	go.opentelemetry.io/otel/exporters/prometheus v0.28.0
 	go.opentelemetry.io/otel/metric v0.28.0
 	go.opentelemetry.io/otel/sdk/metric v0.28.0
diff --git a/example/zipkin/go.mod b/example/zipkin/go.mod
index 907d62c0fe9..225d2f6798d 100644
--- a/example/zipkin/go.mod
+++ b/example/zipkin/go.mod
@@ -9,10 +9,10 @@ replace (
 )
 
 require (
-	go.opentelemetry.io/otel v1.6.0
-	go.opentelemetry.io/otel/exporters/zipkin v1.6.0
-	go.opentelemetry.io/otel/sdk v1.6.0
-	go.opentelemetry.io/otel/trace v1.6.0
+	go.opentelemetry.io/otel v1.6.1
+	go.opentelemetry.io/otel/exporters/zipkin v1.6.1
+	go.opentelemetry.io/otel/sdk v1.6.1
+	go.opentelemetry.io/otel/trace v1.6.1
 )
 
 replace go.opentelemetry.io/otel/bridge/opencensus => ../../bridge/opencensus
diff --git a/exporters/jaeger/go.mod b/exporters/jaeger/go.mod
index cd37734c203..091b208c682 100644
--- a/exporters/jaeger/go.mod
+++ b/exporters/jaeger/go.mod
@@ -5,9 +5,9 @@ go 1.16
 require (
 	github.com/google/go-cmp v0.5.7
 	github.com/stretchr/testify v1.7.1
-	go.opentelemetry.io/otel v1.6.0
-	go.opentelemetry.io/otel/sdk v1.6.0
-	go.opentelemetry.io/otel/trace v1.6.0
+	go.opentelemetry.io/otel v1.6.1
+	go.opentelemetry.io/otel/sdk v1.6.1
+	go.opentelemetry.io/otel/trace v1.6.1
 )
 
 replace go.opentelemetry.io/otel/bridge/opencensus => ../../bridge/opencensus
diff --git a/exporters/otlp/otlpmetric/go.mod b/exporters/otlp/otlpmetric/go.mod
index 86ca0f599a6..18d26170af7 100644
--- a/exporters/otlp/otlpmetric/go.mod
+++ b/exporters/otlp/otlpmetric/go.mod
@@ -5,10 +5,10 @@ go 1.16
 require (
 	github.com/google/go-cmp v0.5.7
 	github.com/stretchr/testify v1.7.1
-	go.opentelemetry.io/otel v1.6.0
-	go.opentelemetry.io/otel/exporters/otlp/internal/retry v1.6.0
+	go.opentelemetry.io/otel v1.6.1
+	go.opentelemetry.io/otel/exporters/otlp/internal/retry v1.6.1
 	go.opentelemetry.io/otel/metric v0.28.0
-	go.opentelemetry.io/otel/sdk v1.6.0
+	go.opentelemetry.io/otel/sdk v1.6.1
 	go.opentelemetry.io/otel/sdk/metric v0.28.0
 	go.opentelemetry.io/proto/otlp v0.12.1
 	google.golang.org/grpc v1.45.0
diff --git a/exporters/otlp/otlpmetric/otlpmetricgrpc/go.mod b/exporters/otlp/otlpmetric/otlpmetricgrpc/go.mod
index e9e177d0322..d354381acc9 100644
--- a/exporters/otlp/otlpmetric/otlpmetricgrpc/go.mod
+++ b/exporters/otlp/otlpmetric/otlpmetricgrpc/go.mod
@@ -4,11 +4,11 @@ go 1.16
 
 require (
 	github.com/stretchr/testify v1.7.1
-	go.opentelemetry.io/otel v1.6.0
-	go.opentelemetry.io/otel/exporters/otlp/internal/retry v1.6.0
+	go.opentelemetry.io/otel v1.6.1
+	go.opentelemetry.io/otel/exporters/otlp/internal/retry v1.6.1
 	go.opentelemetry.io/otel/exporters/otlp/otlpmetric v0.28.0
 	go.opentelemetry.io/otel/metric v0.28.0
-	go.opentelemetry.io/otel/sdk v1.6.0
+	go.opentelemetry.io/otel/sdk v1.6.1
 	go.opentelemetry.io/otel/sdk/metric v0.28.0
 	go.opentelemetry.io/proto/otlp v0.12.1
 	google.golang.org/genproto v0.0.0-20211118181313-81c1377c94b1
diff --git a/exporters/otlp/otlpmetric/otlpmetrichttp/go.mod b/exporters/otlp/otlpmetric/otlpmetrichttp/go.mod
index 9e56f58b67e..3cdee92b241 100644
--- a/exporters/otlp/otlpmetric/otlpmetrichttp/go.mod
+++ b/exporters/otlp/otlpmetric/otlpmetrichttp/go.mod
@@ -4,9 +4,9 @@ go 1.16
 
 require (
 	github.com/stretchr/testify v1.7.1
-	go.opentelemetry.io/otel/exporters/otlp/internal/retry v1.6.0
+	go.opentelemetry.io/otel/exporters/otlp/internal/retry v1.6.1
 	go.opentelemetry.io/otel/exporters/otlp/otlpmetric v0.28.0
-	go.opentelemetry.io/otel/sdk v1.6.0
+	go.opentelemetry.io/otel/sdk v1.6.1
 	go.opentelemetry.io/proto/otlp v0.12.1
 	google.golang.org/protobuf v1.28.0
 )
diff --git a/exporters/otlp/otlptrace/go.mod b/exporters/otlp/otlptrace/go.mod
index 7a449e9c241..b7a02218c69 100644
--- a/exporters/otlp/otlptrace/go.mod
+++ b/exporters/otlp/otlptrace/go.mod
@@ -5,10 +5,10 @@ go 1.16
 require (
 	github.com/google/go-cmp v0.5.7
 	github.com/stretchr/testify v1.7.1
-	go.opentelemetry.io/otel v1.6.0
-	go.opentelemetry.io/otel/exporters/otlp/internal/retry v1.6.0
-	go.opentelemetry.io/otel/sdk v1.6.0
-	go.opentelemetry.io/otel/trace v1.6.0
+	go.opentelemetry.io/otel v1.6.1
+	go.opentelemetry.io/otel/exporters/otlp/internal/retry v1.6.1
+	go.opentelemetry.io/otel/sdk v1.6.1
+	go.opentelemetry.io/otel/trace v1.6.1
 	go.opentelemetry.io/proto/otlp v0.12.1
 	google.golang.org/grpc v1.45.0
 	google.golang.org/protobuf v1.28.0
diff --git a/exporters/otlp/otlptrace/otlptracegrpc/go.mod b/exporters/otlp/otlptrace/otlptracegrpc/go.mod
index 699ae36ef2b..22a9ea67b6d 100644
--- a/exporters/otlp/otlptrace/otlptracegrpc/go.mod
+++ b/exporters/otlp/otlptrace/otlptracegrpc/go.mod
@@ -4,10 +4,10 @@ go 1.16
 
 require (
 	github.com/stretchr/testify v1.7.1
-	go.opentelemetry.io/otel v1.6.0
-	go.opentelemetry.io/otel/exporters/otlp/internal/retry v1.6.0
-	go.opentelemetry.io/otel/exporters/otlp/otlptrace v1.6.0
-	go.opentelemetry.io/otel/sdk v1.6.0
+	go.opentelemetry.io/otel v1.6.1
+	go.opentelemetry.io/otel/exporters/otlp/internal/retry v1.6.1
+	go.opentelemetry.io/otel/exporters/otlp/otlptrace v1.6.1
+	go.opentelemetry.io/otel/sdk v1.6.1
 	go.opentelemetry.io/proto/otlp v0.12.1
 	go.uber.org/goleak v1.1.12
 	google.golang.org/genproto v0.0.0-20211118181313-81c1377c94b1
diff --git a/exporters/otlp/otlptrace/otlptracehttp/go.mod b/exporters/otlp/otlptrace/otlptracehttp/go.mod
index 92f3c3aa79d..b3963de7e32 100644
--- a/exporters/otlp/otlptrace/otlptracehttp/go.mod
+++ b/exporters/otlp/otlptrace/otlptracehttp/go.mod
@@ -4,11 +4,11 @@ go 1.16
 
 require (
 	github.com/stretchr/testify v1.7.1
-	go.opentelemetry.io/otel v1.6.0
-	go.opentelemetry.io/otel/exporters/otlp/internal/retry v1.6.0
-	go.opentelemetry.io/otel/exporters/otlp/otlptrace v1.6.0
-	go.opentelemetry.io/otel/sdk v1.6.0
-	go.opentelemetry.io/otel/trace v1.6.0
+	go.opentelemetry.io/otel v1.6.1
+	go.opentelemetry.io/otel/exporters/otlp/internal/retry v1.6.1
+	go.opentelemetry.io/otel/exporters/otlp/otlptrace v1.6.1
+	go.opentelemetry.io/otel/sdk v1.6.1
+	go.opentelemetry.io/otel/trace v1.6.1
 	go.opentelemetry.io/proto/otlp v0.12.1
 	google.golang.org/protobuf v1.28.0
 )
diff --git a/exporters/prometheus/go.mod b/exporters/prometheus/go.mod
index 700c35dadd3..ddc5dcb9b32 100644
--- a/exporters/prometheus/go.mod
+++ b/exporters/prometheus/go.mod
@@ -5,9 +5,9 @@ go 1.16
 require (
 	github.com/prometheus/client_golang v1.12.1
 	github.com/stretchr/testify v1.7.1
-	go.opentelemetry.io/otel v1.6.0
+	go.opentelemetry.io/otel v1.6.1
 	go.opentelemetry.io/otel/metric v0.28.0
-	go.opentelemetry.io/otel/sdk v1.6.0
+	go.opentelemetry.io/otel/sdk v1.6.1
 	go.opentelemetry.io/otel/sdk/metric v0.28.0
 )
 
diff --git a/exporters/stdout/stdoutmetric/go.mod b/exporters/stdout/stdoutmetric/go.mod
index bc09715fd00..c05efdd7119 100644
--- a/exporters/stdout/stdoutmetric/go.mod
+++ b/exporters/stdout/stdoutmetric/go.mod
@@ -9,9 +9,9 @@ replace (
 
 require (
 	github.com/stretchr/testify v1.7.1
-	go.opentelemetry.io/otel v1.6.0
+	go.opentelemetry.io/otel v1.6.1
 	go.opentelemetry.io/otel/metric v0.28.0
-	go.opentelemetry.io/otel/sdk v1.6.0
+	go.opentelemetry.io/otel/sdk v1.6.1
 	go.opentelemetry.io/otel/sdk/metric v0.28.0
 )
 
diff --git a/exporters/stdout/stdouttrace/go.mod b/exporters/stdout/stdouttrace/go.mod
index c158e33d58e..aadba86c81d 100644
--- a/exporters/stdout/stdouttrace/go.mod
+++ b/exporters/stdout/stdouttrace/go.mod
@@ -9,9 +9,9 @@ replace (
 
 require (
 	github.com/stretchr/testify v1.7.1
-	go.opentelemetry.io/otel v1.6.0
-	go.opentelemetry.io/otel/sdk v1.6.0
-	go.opentelemetry.io/otel/trace v1.6.0
+	go.opentelemetry.io/otel v1.6.1
+	go.opentelemetry.io/otel/sdk v1.6.1
+	go.opentelemetry.io/otel/trace v1.6.1
 )
 
 replace go.opentelemetry.io/otel/bridge/opencensus => ../../../bridge/opencensus
diff --git a/exporters/zipkin/go.mod b/exporters/zipkin/go.mod
index a11a0efbcbe..a83141ced15 100644
--- a/exporters/zipkin/go.mod
+++ b/exporters/zipkin/go.mod
@@ -6,9 +6,9 @@ require (
 	github.com/google/go-cmp v0.5.7
 	github.com/openzipkin/zipkin-go v0.4.0
 	github.com/stretchr/testify v1.7.1
-	go.opentelemetry.io/otel v1.6.0
-	go.opentelemetry.io/otel/sdk v1.6.0
-	go.opentelemetry.io/otel/trace v1.6.0
+	go.opentelemetry.io/otel v1.6.1
+	go.opentelemetry.io/otel/sdk v1.6.1
+	go.opentelemetry.io/otel/trace v1.6.1
 )
 
 replace go.opentelemetry.io/otel/bridge/opencensus => ../../bridge/opencensus
diff --git a/go.mod b/go.mod
index 6b238c8749a..eba789c09f7 100644
--- a/go.mod
+++ b/go.mod
@@ -7,7 +7,7 @@ require (
 	github.com/go-logr/stdr v1.2.2
 	github.com/google/go-cmp v0.5.7
 	github.com/stretchr/testify v1.7.1
-	go.opentelemetry.io/otel/trace v1.6.0
+	go.opentelemetry.io/otel/trace v1.6.1
 )
 
 replace go.opentelemetry.io/otel => ./
diff --git a/metric/go.mod b/metric/go.mod
index b561560bc97..a34701e6781 100644
--- a/metric/go.mod
+++ b/metric/go.mod
@@ -4,7 +4,7 @@ go 1.16
 
 require (
 	github.com/stretchr/testify v1.7.1
-	go.opentelemetry.io/otel v1.6.0
+	go.opentelemetry.io/otel v1.6.1
 )
 
 replace go.opentelemetry.io/otel => ../
diff --git a/sdk/export/metric/go.mod b/sdk/export/metric/go.mod
index aa2e6a7952a..7dff9c294e4 100644
--- a/sdk/export/metric/go.mod
+++ b/sdk/export/metric/go.mod
@@ -40,7 +40,7 @@ replace go.opentelemetry.io/otel/sdk/metric => ../../metric
 replace go.opentelemetry.io/otel/trace => ../../../trace
 
 require (
-	go.opentelemetry.io/otel v1.6.0
+	go.opentelemetry.io/otel v1.6.1
 	go.opentelemetry.io/otel/sdk/metric v0.28.0
 )
 
diff --git a/sdk/go.mod b/sdk/go.mod
index fd9f349a974..c0c3e98d1ef 100644
--- a/sdk/go.mod
+++ b/sdk/go.mod
@@ -8,8 +8,8 @@ require (
 	github.com/go-logr/logr v1.2.3
 	github.com/google/go-cmp v0.5.7
 	github.com/stretchr/testify v1.7.1
-	go.opentelemetry.io/otel v1.6.0
-	go.opentelemetry.io/otel/trace v1.6.0
+	go.opentelemetry.io/otel v1.6.1
+	go.opentelemetry.io/otel/trace v1.6.1
 	golang.org/x/sys v0.0.0-20210423185535-09eb48e85fd7
 )
 
diff --git a/sdk/metric/go.mod b/sdk/metric/go.mod
index 52656af7bc8..92ac0a3aab8 100644
--- a/sdk/metric/go.mod
+++ b/sdk/metric/go.mod
@@ -41,9 +41,9 @@ replace go.opentelemetry.io/otel/trace => ../../trace
 require (
 	github.com/benbjohnson/clock v1.3.0
 	github.com/stretchr/testify v1.7.1
-	go.opentelemetry.io/otel v1.6.0
+	go.opentelemetry.io/otel v1.6.1
 	go.opentelemetry.io/otel/metric v0.28.0
-	go.opentelemetry.io/otel/sdk v1.6.0
+	go.opentelemetry.io/otel/sdk v1.6.1
 )
 
 replace go.opentelemetry.io/otel/example/passthrough => ../../example/passthrough
diff --git a/trace/go.mod b/trace/go.mod
index e9346b27464..97ad4d13993 100644
--- a/trace/go.mod
+++ b/trace/go.mod
@@ -41,7 +41,7 @@ replace go.opentelemetry.io/otel/trace => ./
 require (
 	github.com/google/go-cmp v0.5.7
 	github.com/stretchr/testify v1.7.1
-	go.opentelemetry.io/otel v1.6.0
+	go.opentelemetry.io/otel v1.6.1
 )
 
 replace go.opentelemetry.io/otel/example/passthrough => ../example/passthrough
diff --git a/version.go b/version.go
index bfcd5a0e493..70f6bed1e8f 100644
--- a/version.go
+++ b/version.go
@@ -16,5 +16,5 @@ package otel // import "go.opentelemetry.io/otel"
 
 // Version is the current release version of OpenTelemetry in use.
 func Version() string {
-	return "1.6.0"
+	return "1.6.1"
 }
diff --git a/versions.yaml b/versions.yaml
index 2ed0030ea5a..d6d593bf5fc 100644
--- a/versions.yaml
+++ b/versions.yaml
@@ -14,7 +14,7 @@
 
 module-sets:
   stable-v1:
-    version: v1.6.0
+    version: v1.6.1
     modules:
       - go.opentelemetry.io/otel
       - go.opentelemetry.io/otel/bridge/opentracing