diff --git a/plugins/node/opentelemetry-instrumentation-graphql/src/instrumentation.ts b/plugins/node/opentelemetry-instrumentation-graphql/src/instrumentation.ts
index d8b2db0628..a5819b1e87 100644
--- a/plugins/node/opentelemetry-instrumentation-graphql/src/instrumentation.ts
+++ b/plugins/node/opentelemetry-instrumentation-graphql/src/instrumentation.ts
@@ -229,8 +229,8 @@ export class GraphQLInstrumentation extends InstrumentationBase {
                 processedArgs,
               ]);
             },
-            err => {
-              endSpan(span, err);
+            (err, result) => {
+              instrumentation._handleExecutionResult(span, err, result);
             }
           );
         });
@@ -238,6 +238,50 @@ export class GraphQLInstrumentation extends InstrumentationBase {
     };
   }
 
+  private _handleExecutionResult(
+    span: api.Span,
+    err?: Error,
+    result?: PromiseOrValue<graphqlTypes.ExecutionResult>
+  ) {
+    const config = this._getConfig();
+    if (
+      typeof config.responseHook !== 'function' ||
+      result === undefined ||
+      err
+    ) {
+      endSpan(span, err);
+      return;
+    }
+
+    if (result.constructor.name === 'Promise') {
+      (result as Promise<graphqlTypes.ExecutionResult>).then(resultData => {
+        this._executeResponseHook(span, resultData);
+      });
+    } else {
+      this._executeResponseHook(span, result as graphqlTypes.ExecutionResult);
+    }
+  }
+
+  private _executeResponseHook(
+    span: api.Span,
+    result: graphqlTypes.ExecutionResult
+  ) {
+    const config = this._getConfig();
+    safeExecuteInTheMiddle(
+      () => {
+        config.responseHook(span, result);
+      },
+      err => {
+        if (err) {
+          api.diag.error('Error running response hook', err);
+        }
+
+        endSpan(span, undefined);
+      },
+      true
+    );
+  }
+
   private _patchParse(): (original: parseType) => parseType {
     const instrumentation = this;
     return function parse(original) {
diff --git a/plugins/node/opentelemetry-instrumentation-graphql/src/types.ts b/plugins/node/opentelemetry-instrumentation-graphql/src/types.ts
index 39bbebf17f..26265cc372 100644
--- a/plugins/node/opentelemetry-instrumentation-graphql/src/types.ts
+++ b/plugins/node/opentelemetry-instrumentation-graphql/src/types.ts
@@ -29,6 +29,10 @@ import { OTEL_GRAPHQL_DATA_SYMBOL, OTEL_PATCHED_SYMBOL } from './symbols';
 export const OPERATION_NOT_SUPPORTED =
   'Operation$operationName$not' + ' supported';
 
+export interface GraphQLInstrumentationExecutionResponseHook {
+  (span: api.Span, data: graphqlTypes.ExecutionResult): void;
+}
+
 export interface GraphQLInstrumentationConfig extends InstrumentationConfig {
   /**
    * When set to true it will not remove attributes values from schema source.
@@ -53,6 +57,14 @@ export interface GraphQLInstrumentationConfig extends InstrumentationConfig {
    * @default false
    */
   mergeItems?: boolean;
+
+  /**
+   * Hook that allows adding custom span attributes based on the data
+   * returned from "execute" GraphQL action.
+   *
+   * @default undefined
+   */
+  responseHook?: GraphQLInstrumentationExecutionResponseHook;
 }
 
 /**
diff --git a/plugins/node/opentelemetry-instrumentation-graphql/test/graphql.test.ts b/plugins/node/opentelemetry-instrumentation-graphql/test/graphql.test.ts
index 64dc6c72af..51ac5a9bee 100644
--- a/plugins/node/opentelemetry-instrumentation-graphql/test/graphql.test.ts
+++ b/plugins/node/opentelemetry-instrumentation-graphql/test/graphql.test.ts
@@ -20,11 +20,16 @@ import {
   ReadableSpan,
   SimpleSpanProcessor,
 } from '@opentelemetry/tracing';
+import { Span } from '@opentelemetry/api';
 import * as assert from 'assert';
+import type * as graphqlTypes from 'graphql';
 import { GraphQLInstrumentation } from '../src';
 import { SpanNames } from '../src/enum';
 import { AttributeNames } from '../src/enums/AttributeNames';
-import { GraphQLInstrumentationConfig } from '../src/types';
+import {
+  GraphQLInstrumentationConfig,
+  GraphQLInstrumentationExecutionResponseHook,
+} from '../src/types';
 import { assertResolveSpan } from './helper';
 
 const defaultConfig: GraphQLInstrumentationConfig = {};
@@ -971,6 +976,74 @@ describe('graphql', () => {
     });
   });
 
+  describe('responseHook', () => {
+    let spans: ReadableSpan[];
+    let graphqlResult: graphqlTypes.ExecutionResult;
+    const dataAttributeName = 'graphql_data';
+
+    afterEach(() => {
+      exporter.reset();
+      graphQLInstrumentation.disable();
+      spans = [];
+    });
+
+    describe('when responseHook is valid', () => {
+      beforeEach(async () => {
+        create({
+          responseHook: (span: Span, data: graphqlTypes.ExecutionResult) => {
+            span.setAttribute(dataAttributeName, JSON.stringify(data));
+          },
+        });
+        graphqlResult = await graphql(schema, sourceList1);
+        spans = exporter.getFinishedSpans();
+      });
+
+      it('should attach response hook data to the resulting spans', () => {
+        const querySpan = spans.find(
+          span => span.attributes['graphql.operation.name'] == 'query'
+        );
+        const instrumentationResult = querySpan?.attributes[dataAttributeName];
+        assert.deepStrictEqual(
+          instrumentationResult,
+          JSON.stringify(graphqlResult)
+        );
+      });
+    });
+
+    describe('when responseHook throws an error', () => {
+      beforeEach(async () => {
+        create({
+          responseHook: (_span: Span, _data: graphqlTypes.ExecutionResult) => {
+            throw 'some kind of failure!';
+          },
+        });
+        graphqlResult = await graphql(schema, sourceList1);
+        spans = exporter.getFinishedSpans();
+      });
+
+      it('should not do any harm', () => {
+        assert.deepStrictEqual(graphqlResult.data?.books?.length, 13);
+      });
+    });
+
+    describe('when responseHook is not a function', () => {
+      beforeEach(async () => {
+        // Cast to unknown so that it's possible to cast to GraphQLInstrumentationExecutionResponseHook later
+        const invalidTypeHook = 1234 as unknown;
+        create({
+          responseHook:
+            invalidTypeHook as GraphQLInstrumentationExecutionResponseHook,
+        });
+        graphqlResult = await graphql(schema, sourceList1);
+        spans = exporter.getFinishedSpans();
+      });
+
+      it('should not do any harm', () => {
+        assert.deepStrictEqual(graphqlResult.data?.books?.length, 13);
+      });
+    });
+  });
+
   describe('when query operation is not supported', () => {
     let spans: ReadableSpan[];