diff --git a/packages/opentelemetry-instrumentation/src/platform/node/instrumentation.ts b/packages/opentelemetry-instrumentation/src/platform/node/instrumentation.ts
index f50cff4252..d03afadb93 100644
--- a/packages/opentelemetry-instrumentation/src/platform/node/instrumentation.ts
+++ b/packages/opentelemetry-instrumentation/src/platform/node/instrumentation.ts
@@ -17,7 +17,7 @@
 import * as types from '../../types';
 import * as path from 'path';
 import * as RequireInTheMiddle from 'require-in-the-middle';
-import * as semver from 'semver';
+import { satisfies } from 'semver';
 import { InstrumentationAbstract } from '../../instrumentation';
 import { InstrumentationModuleDefinition } from './types';
 import { diag } from '@opentelemetry/api';
@@ -50,7 +50,7 @@ export abstract class InstrumentationBase<T = any>
     if (this._modules.length === 0) {
       diag.warn(
         'No modules instrumentation has been defined,' +
-          ' nothing will be patched'
+        ' nothing will be patched'
       );
     }
 
@@ -80,7 +80,7 @@ export abstract class InstrumentationBase<T = any>
       // main module
       if (
         typeof version === 'string' &&
-        isSupported(module.supportedVersions, version)
+        isSupported(module.supportedVersions, version, module.includePrerelease)
       ) {
         if (typeof module.patch === 'function') {
           module.moduleExports = exports;
@@ -93,7 +93,7 @@ export abstract class InstrumentationBase<T = any>
       // internal file
       const files = module.files ?? [];
       const file = files.find(file => file.name === name);
-      if (file && isSupported(file.supportedVersions, version)) {
+      if (file && isSupported(file.supportedVersions, version, module.includePrerelease)) {
         file.moduleExports = exports;
         if (this._enabled) {
           return file.patch(exports, module.moduleVersion);
@@ -167,8 +167,8 @@ export abstract class InstrumentationBase<T = any>
   }
 }
 
-function isSupported(supportedVersions: string[], version: string): boolean {
+function isSupported(supportedVersions: string[], version: string, includePrerelease?: boolean): boolean {
   return supportedVersions.some(supportedVersion => {
-    return semver.satisfies(version, supportedVersion);
+    return satisfies(version, supportedVersion, { includePrerelease });
   });
 }
diff --git a/packages/opentelemetry-instrumentation/src/platform/node/types.ts b/packages/opentelemetry-instrumentation/src/platform/node/types.ts
index 972659bf00..c5ea980c30 100644
--- a/packages/opentelemetry-instrumentation/src/platform/node/types.ts
+++ b/packages/opentelemetry-instrumentation/src/platform/node/types.ts
@@ -47,6 +47,9 @@ export interface InstrumentationModuleDefinition<T> {
   /** Module internal files to be patched  */
   files: InstrumentationModuleFile<any>[];
 
+  /** If set to true, the includePrerelease check will be included when calling semver.satisfies */
+  includePrerelease?: boolean;
+
   /** Method to patch the instrumentation  */
   patch?: (moduleExports: T, moduleVersion?: string) => T;