diff --git a/packages/core/cache/src/FSCache.js b/packages/core/cache/src/FSCache.js
index ef7ba6da5db..43ae406ceb8 100644
--- a/packages/core/cache/src/FSCache.js
+++ b/packages/core/cache/src/FSCache.js
@@ -41,13 +41,13 @@ export class FSCache implements Cache {
   }
 
   getStream(key: string): Readable {
-    return this.fs.createReadStream(this._getCachePath(key));
+    return this.fs.createReadStream(this._getCachePath(`${key}-large`));
   }
 
   setStream(key: string, stream: Readable): Promise<void> {
     return new Promise((resolve, reject) => {
       stream
-        .pipe(this.fs.createWriteStream(this._getCachePath(key)))
+        .pipe(this.fs.createWriteStream(this._getCachePath(`${key}-large`)))
         .on('error', reject)
         .on('finish', resolve);
     });
@@ -77,6 +77,18 @@ export class FSCache implements Cache {
     }
   }
 
+  hasLargeBlob(key: string): Promise<boolean> {
+    return this.fs.exists(this._getCachePath(`${key}-large`));
+  }
+
+  getLargeBlob(key: string): Promise<Buffer> {
+    return this.fs.readFile(this._getCachePath(`${key}-large`));
+  }
+
+  async setLargeBlob(key: string, contents: Buffer | string): Promise<void> {
+    await this.fs.writeFile(this._getCachePath(`${key}-large`), contents);
+  }
+
   async get<T>(key: string): Promise<?T> {
     try {
       let data = await this.fs.readFile(this._getCachePath(key));
diff --git a/packages/core/cache/src/LMDBCache.js b/packages/core/cache/src/LMDBCache.js
index 747ad49ad73..16ab8d54f91 100644
--- a/packages/core/cache/src/LMDBCache.js
+++ b/packages/core/cache/src/LMDBCache.js
@@ -1,21 +1,24 @@
 // @flow strict-local
-import type {Readable} from 'stream';
 import type {FilePath} from '@parcel/types';
 import type {Cache} from './types';
 
+import {Readable} from 'stream';
+import path from 'path';
 import {serialize, deserialize, registerSerializableClass} from '@parcel/core';
-import {blobToStream, bufferStream} from '@parcel/utils';
+import {NodeFS} from '@parcel/fs';
 // flowlint-next-line untyped-import:off
 import packageJson from '../package.json';
 // $FlowFixMe
 import lmdb from 'lmdb-store';
 
 export class LMDBCache implements Cache {
+  fs: NodeFS;
   dir: FilePath;
   // $FlowFixMe
   store: any;
 
   constructor(cacheDir: FilePath) {
+    this.fs = new NodeFS();
     this.dir = cacheDir;
 
     this.store = lmdb.open(cacheDir, {
@@ -53,16 +56,20 @@ export class LMDBCache implements Cache {
   }
 
   async set(key: string, value: mixed): Promise<void> {
-    await this.store.put(key, serialize(value));
+    await this.setBlob(key, serialize(value));
   }
 
   getStream(key: string): Readable {
-    return blobToStream(this.store.get(key));
+    return this.fs.createReadStream(path.join(this.dir, key));
   }
 
-  async setStream(key: string, stream: Readable): Promise<void> {
-    let buf = await bufferStream(stream);
-    await this.store.put(key, buf);
+  setStream(key: string, stream: Readable): Promise<void> {
+    return new Promise((resolve, reject) => {
+      stream
+        .pipe(this.fs.createWriteStream(path.join(this.dir, key)))
+        .on('error', reject)
+        .on('finish', resolve);
+    });
   }
 
   getBlob(key: string): Promise<Buffer> {
@@ -79,6 +86,18 @@ export class LMDBCache implements Cache {
   getBuffer(key: string): Promise<?Buffer> {
     return Promise.resolve(this.store.get(key));
   }
+
+  hasLargeBlob(key: string): Promise<boolean> {
+    return this.fs.exists(path.join(this.dir, key));
+  }
+
+  getLargeBlob(key: string): Promise<Buffer> {
+    return this.fs.readFile(path.join(this.dir, key));
+  }
+
+  async setLargeBlob(key: string, contents: Buffer | string): Promise<void> {
+    await this.fs.writeFile(path.join(this.dir, key), contents);
+  }
 }
 
 registerSerializableClass(`${packageJson.version}:LMDBCache`, LMDBCache);
diff --git a/packages/core/cache/src/types.js b/packages/core/cache/src/types.js
index 5f591388048..1211daf844b 100644
--- a/packages/core/cache/src/types.js
+++ b/packages/core/cache/src/types.js
@@ -10,5 +10,8 @@ export interface Cache {
   setStream(key: string, stream: Readable): Promise<void>;
   getBlob(key: string): Promise<Buffer>;
   setBlob(key: string, contents: Buffer | string): Promise<void>;
+  hasLargeBlob(key: string): Promise<boolean>;
+  getLargeBlob(key: string): Promise<Buffer>;
+  setLargeBlob(key: string, contents: Buffer | string): Promise<void>;
   getBuffer(key: string): Promise<?Buffer>;
 }
diff --git a/packages/core/core/src/CommittedAsset.js b/packages/core/core/src/CommittedAsset.js
index 8d97839b068..9bc94e3adf4 100644
--- a/packages/core/core/src/CommittedAsset.js
+++ b/packages/core/core/src/CommittedAsset.js
@@ -27,7 +27,11 @@ export default class CommittedAsset {
   getContent(): Blob | Promise<Buffer | string> {
     if (this.content == null) {
       if (this.value.contentKey != null) {
-        return this.options.cache.getStream(this.value.contentKey);
+        if (this.value.isLargeBlob) {
+          return this.options.cache.getStream(this.value.contentKey);
+        } else {
+          return this.options.cache.getBlob(this.value.contentKey);
+        }
       } else if (this.value.astKey != null) {
         return streamFromPromise(
           generateFromAST(this).then(({content}) => {
diff --git a/packages/core/core/src/PackagerRunner.js b/packages/core/core/src/PackagerRunner.js
index c062edc9da4..a2b778e05a2 100644
--- a/packages/core/core/src/PackagerRunner.js
+++ b/packages/core/core/src/PackagerRunner.js
@@ -83,6 +83,7 @@ export type BundleInfo = {|
   +hashReferences: Array<string>,
   +time?: number,
   +cacheKeys: CacheKeyMap,
+  +isLargeBlob: boolean,
 |};
 
 type CacheKeyMap = {|
@@ -596,7 +597,9 @@ export default class PackagerRunner {
     let contentKey = PackagerRunner.getContentKey(cacheKey);
     let mapKey = PackagerRunner.getMapKey(cacheKey);
 
-    let contentExists = await this.options.cache.has(contentKey);
+    let isLargeBlob = await this.options.cache.hasLargeBlob(contentKey);
+    let contentExists =
+      isLargeBlob || (await this.options.cache.has(contentKey));
     if (!contentExists) {
       return null;
     }
@@ -604,8 +607,12 @@ export default class PackagerRunner {
     let mapExists = await this.options.cache.has(mapKey);
 
     return {
-      contents: this.options.cache.getStream(contentKey),
-      map: mapExists ? this.options.cache.getStream(mapKey) : null,
+      contents: isLargeBlob
+        ? this.options.cache.getStream(contentKey)
+        : blobToStream(await this.options.cache.getBlob(contentKey)),
+      map: mapExists
+        ? blobToStream(await this.options.cache.getBlob(mapKey))
+        : null,
     };
   }
 
@@ -618,9 +625,11 @@ export default class PackagerRunner {
     let size = 0;
     let hash;
     let hashReferences = [];
+    let isLargeBlob = false;
 
     // TODO: don't replace hash references in binary files??
     if (contents instanceof Readable) {
+      isLargeBlob = true;
       let boundaryStr = '';
       let h = new Hash();
       await this.options.cache.setStream(
@@ -659,6 +668,7 @@ export default class PackagerRunner {
       hash,
       hashReferences,
       cacheKeys,
+      isLargeBlob,
     };
     await this.options.cache.set(cacheKeys.info, info);
     return info;
diff --git a/packages/core/core/src/RequestTracker.js b/packages/core/core/src/RequestTracker.js
index 98f729b30d7..00a950e00dd 100644
--- a/packages/core/core/src/RequestTracker.js
+++ b/packages/core/core/src/RequestTracker.js
@@ -29,6 +29,7 @@ import {
 } from '@parcel/utils';
 import {hashString} from '@parcel/hash';
 import {ContentGraph} from '@parcel/graph';
+import {deserialize, serialize} from './serializer';
 import {assertSignalNotAborted, hashFromOption} from './utils';
 import {
   type ProjectPath,
@@ -856,10 +857,11 @@ export default class RequestTracker {
       let result: T = (node.value.result: any);
       return result;
     } else if (node.value.resultCacheKey != null && ifMatch == null) {
-      let cachedResult: T = (nullthrows(
-        await this.options.cache.get(node.value.resultCacheKey),
-        // $FlowFixMe
-      ): any);
+      let key = node.value.resultCacheKey;
+      invariant(this.options.cache.hasLargeBlob(key));
+      let cachedResult: T = deserialize(
+        await this.options.cache.getLargeBlob(key),
+      );
       node.value.result = cachedResult;
       return cachedResult;
     }
@@ -1050,13 +1052,18 @@ export default class RequestTracker {
       let resultCacheKey = node.value.resultCacheKey;
       if (resultCacheKey != null && node.value.result != null) {
         promises.push(
-          this.options.cache.set(resultCacheKey, node.value.result),
+          this.options.cache.setLargeBlob(
+            resultCacheKey,
+            serialize(node.value.result),
+          ),
         );
         delete node.value.result;
       }
     }
 
-    promises.push(this.options.cache.set(requestGraphKey, this.graph));
+    promises.push(
+      this.options.cache.setLargeBlob(requestGraphKey, serialize(this.graph)),
+    );
 
     let opts = getWatcherOptions(this.options);
     let snapshotPath = path.join(this.options.cacheDir, snapshotKey + '.txt');
@@ -1100,9 +1107,10 @@ async function loadRequestGraph(options): Async<RequestGraph> {
 
   let cacheKey = getCacheKey(options);
   let requestGraphKey = hashString(`${cacheKey}:requestGraph`);
-  let requestGraph = await options.cache.get<RequestGraph>(requestGraphKey);
-
-  if (requestGraph) {
+  if (await options.cache.hasLargeBlob(requestGraphKey)) {
+    let requestGraph: RequestGraph = deserialize(
+      await options.cache.getLargeBlob(requestGraphKey),
+    );
     let opts = getWatcherOptions(options);
     let snapshotKey = hashString(`${cacheKey}:snapshot`);
     let snapshotPath = path.join(options.cacheDir, snapshotKey + '.txt');
diff --git a/packages/core/core/src/Transformation.js b/packages/core/core/src/Transformation.js
index bdd18698f51..f2c0fab4f01 100644
--- a/packages/core/core/src/Transformation.js
+++ b/packages/core/core/src/Transformation.js
@@ -512,7 +512,9 @@ export default class Transformation {
       cachedAssets.map(async (value: AssetValue) => {
         let content =
           value.contentKey != null
-            ? this.options.cache.getStream(value.contentKey)
+            ? value.isLargeBlob
+              ? this.options.cache.getStream(value.contentKey)
+              : await this.options.cache.getBlob(value.contentKey)
             : null;
         let mapBuffer =
           value.astKey != null
diff --git a/packages/core/core/src/UncommittedAsset.js b/packages/core/core/src/UncommittedAsset.js
index ec199e6ca68..cd0fc9be2b6 100644
--- a/packages/core/core/src/UncommittedAsset.js
+++ b/packages/core/core/src/UncommittedAsset.js
@@ -135,6 +135,7 @@ export default class UncommittedAsset {
       this.value.stats.size = size;
     }
 
+    this.value.isLargeBlob = this.content instanceof Readable;
     this.value.committed = true;
   }
 
diff --git a/packages/core/core/src/requests/WriteBundleRequest.js b/packages/core/core/src/requests/WriteBundleRequest.js
index 80a997b41b7..b87e7a8afd3 100644
--- a/packages/core/core/src/requests/WriteBundleRequest.js
+++ b/packages/core/core/src/requests/WriteBundleRequest.js
@@ -16,7 +16,7 @@ import {HASH_REF_PREFIX, HASH_REF_REGEX} from '../constants';
 import nullthrows from 'nullthrows';
 import path from 'path';
 import {NamedBundle} from '../public/Bundle';
-import {TapStream} from '@parcel/utils';
+import {blobToStream, TapStream} from '@parcel/utils';
 import {Readable, Transform, pipeline} from 'stream';
 import {
   fromProjectPath,
@@ -123,7 +123,14 @@ async function run({input, options, api}: RunInput) {
       : {
           mode: (await inputFS.stat(mainEntry.filePath)).mode,
         };
-  let contentStream = options.cache.getStream(cacheKeys.content);
+  let contentStream: Readable;
+  if (info.isLargeBlob) {
+    contentStream = options.cache.getStream(cacheKeys.content);
+  } else {
+    contentStream = blobToStream(
+      await options.cache.getBlob(cacheKeys.content),
+    );
+  }
   let size = 0;
   contentStream = contentStream.pipe(
     new TapStream(buf => {
@@ -159,7 +166,7 @@ async function run({input, options, api}: RunInput) {
     (await options.cache.has(mapKey))
   ) {
     await writeFiles(
-      options.cache.getStream(mapKey),
+      blobToStream(await options.cache.getBlob(mapKey)),
       info,
       hashRefToNameHash,
       options,
diff --git a/packages/core/core/src/types.js b/packages/core/core/src/types.js
index 6c498c47385..a93ffd73293 100644
--- a/packages/core/core/src/types.js
+++ b/packages/core/core/src/types.js
@@ -180,6 +180,7 @@ export type Asset = {|
   configPath?: ProjectPath,
   plugin: ?PackageName,
   configKeyPath?: string,
+  isLargeBlob?: boolean,
 |};
 
 export type InternalGlob = ProjectPath;