diff --git a/packages/browsers/src/browser-data/firefox.ts b/packages/browsers/src/browser-data/firefox.ts
index 33033cc8fe326..7c816c4284801 100644
--- a/packages/browsers/src/browser-data/firefox.ts
+++ b/packages/browsers/src/browser-data/firefox.ts
@@ -220,12 +220,6 @@ function defaultProfilePreferences(
     // Make sure opening about:addons will not hit the network
     'extensions.webservice.discoverURL': `http://${server}/dummy/discoveryURL`,
 
-    // Temporarily force disable BFCache in parent (https://bit.ly/bug-1732263)
-    'fission.bfcacheInParent': false,
-
-    // Force all web content to use a single content process
-    'fission.webContentIsolationStrategy': 0,
-
     // Allow the application to have focus even it runs in the background
     'focusmanager.testmode': true,
     // Disable useragent updates
diff --git a/packages/puppeteer-core/src/node/FirefoxLauncher.ts b/packages/puppeteer-core/src/node/FirefoxLauncher.ts
index e7ebe9f43b749..cd610d2451648 100644
--- a/packages/puppeteer-core/src/node/FirefoxLauncher.ts
+++ b/packages/puppeteer-core/src/node/FirefoxLauncher.ts
@@ -113,7 +113,21 @@ export class FirefoxLauncher extends ProductLauncher {
 
     await createProfile(SupportedBrowsers.FIREFOX, {
       path: userDataDir,
-      preferences: extraPrefsFirefox,
+      preferences: {
+        ...extraPrefsFirefox,
+        ...(options.protocol === 'cdp'
+          ? {
+              // Temporarily force disable BFCache in parent (https://bit.ly/bug-1732263)
+              'fission.bfcacheInParent': false,
+            }
+          : {}),
+        // Force all web content to use a single content process. TODO: remove
+        // this once Firefox supports mouse event dispatch from the main frame
+        // context. Once this happens, webContentIsolationStrategy should only
+        // be set for CDP. See
+        // https://bugzilla.mozilla.org/show_bug.cgi?id=1773393
+        'fission.webContentIsolationStrategy': 0,
+      },
     });
 
     let firefoxExecutable: string;
diff --git a/test/TestExpectations.json b/test/TestExpectations.json
index 0106f550496c4..b56c35c90d3f3 100644
--- a/test/TestExpectations.json
+++ b/test/TestExpectations.json
@@ -2765,12 +2765,24 @@
     "parameters": ["cdp", "firefox"],
     "expectations": ["FAIL"]
   },
+  {
+    "testIdPattern": "[oopif.spec] OOPIF clickablePoint, boundingBox, boxModel should work for elements inside OOPIFs",
+    "platforms": ["darwin", "linux", "win32"],
+    "parameters": ["firefox", "webDriverBiDi"],
+    "expectations": ["PASS"]
+  },
   {
     "testIdPattern": "[oopif.spec] OOPIF should keep track of a frames OOP state",
     "platforms": ["darwin", "linux", "win32"],
     "parameters": ["firefox", "webDriverBiDi"],
     "expectations": ["PASS"]
   },
+  {
+    "testIdPattern": "[oopif.spec] OOPIF should provide access to elements",
+    "platforms": ["darwin", "linux", "win32"],
+    "parameters": ["firefox", "webDriverBiDi"],
+    "expectations": ["PASS"]
+  },
   {
     "testIdPattern": "[oopif.spec] OOPIF should support lazy OOP frames",
     "platforms": ["darwin", "linux", "win32"],