diff --git a/packages/client/lib/client/index.spec.ts b/packages/client/lib/client/index.spec.ts
index b608c7c092c..a0824e440ba 100644
--- a/packages/client/lib/client/index.spec.ts
+++ b/packages/client/lib/client/index.spec.ts
@@ -607,11 +607,41 @@ describe('Client', () => {
         }
     });
 
-    testUtils.testWithClient('executeIsolated', async client => {
-        const id = await client.clientId(),
-            isolatedId = await client.executeIsolated(isolatedClient => isolatedClient.clientId());
-        assert.ok(id !== isolatedId);
-    }, GLOBAL.SERVERS.OPEN);
+    describe('isolationPool', () => {
+        testUtils.testWithClient('executeIsolated', async client => {
+            const id = await client.clientId(),
+                isolatedId = await client.executeIsolated(isolatedClient => isolatedClient.clientId());
+            assert.ok(id !== isolatedId);
+        }, GLOBAL.SERVERS.OPEN);
+
+        testUtils.testWithClient('should be able to use pool even before connect', async client => {
+            await client.executeIsolated(() => Promise.resolve());
+            // make sure to destroy isolation pool
+            await client.connect();
+            await client.disconnect();
+        }, {
+            ...GLOBAL.SERVERS.OPEN,
+            disableClientSetup: true
+        });
+
+        testUtils.testWithClient('should work after reconnect (#2406)', async client => {
+            await client.disconnect();
+            await client.connect();
+            await client.executeIsolated(() => Promise.resolve());
+        }, GLOBAL.SERVERS.OPEN);
+
+        testUtils.testWithClient('should throw ClientClosedError after disconnect', async client => {
+            await client.connect();
+            await client.disconnect();
+            await assert.rejects(
+                client.executeIsolated(() => Promise.resolve()),
+                ClientClosedError
+            );
+        }, {
+            ...GLOBAL.SERVERS.OPEN,
+            disableClientSetup: true
+        });
+    });
 
     async function killClient<
         M extends RedisModules,
@@ -731,7 +761,7 @@ describe('Client', () => {
             members.map<MemberTuple>(member => [member.value, member.score]).sort(sort)
         );
     }, GLOBAL.SERVERS.OPEN);
-
+    
     describe('PubSub', () => {
         testUtils.testWithClient('should be able to publish and subscribe to messages', async publisher => {
             function assertStringListener(message: string, channel: string) {
diff --git a/packages/client/lib/client/index.ts b/packages/client/lib/client/index.ts
index 5dd386647ef..5b9badf3f37 100644
--- a/packages/client/lib/client/index.ts
+++ b/packages/client/lib/client/index.ts
@@ -15,7 +15,6 @@ import { ClientClosedError, ClientOfflineError, DisconnectsClientError } from '.
 import { URL } from 'url';
 import { TcpSocketConnectOpts } from 'net';
 import { PubSubType, PubSubListener, PubSubTypeListeners, ChannelListeners } from './pub-sub';
-import { callbackify } from 'util';
 
 export interface RedisClientOptions<
     M extends RedisModules = RedisModules,
@@ -190,7 +189,7 @@ export default class RedisClient<
     readonly #options?: RedisClientOptions<M, F, S>;
     readonly #socket: RedisSocket;
     readonly #queue: RedisCommandsQueue;
-    readonly #isolationPool: Pool<RedisClientType<M, F, S>>;
+    #isolationPool?: Pool<RedisClientType<M, F, S>>;
     readonly #v4: Record<string, any> = {};
     #selectedDB = 0;
 
@@ -223,16 +222,9 @@ export default class RedisClient<
         this.#options = this.#initiateOptions(options);
         this.#queue = this.#initiateQueue();
         this.#socket = this.#initiateSocket();
-        this.#isolationPool = createPool({
-            create: async () => {
-                const duplicate = this.duplicate({
-                    isolationPoolOptions: undefined
-                }).on('error', err => this.emit('error', err));
-                await duplicate.connect();
-                return duplicate;
-            },
-            destroy: client => client.disconnect()
-        }, options?.isolationPoolOptions);
+        // should be initiated in connect, not here
+        // TODO: consider breaking in v5
+        this.#isolationPool = this.#initiateIsolationPool();
         this.#legacyMode();
     }
 
@@ -337,6 +329,19 @@ export default class RedisClient<
             .on('end', () => this.emit('end'));
     }
 
+    #initiateIsolationPool() {
+        return createPool({
+            create: async () => {
+                const duplicate = this.duplicate({
+                    isolationPoolOptions: undefined
+                }).on('error', err => this.emit('error', err));
+                await duplicate.connect();
+                return duplicate;
+            },
+            destroy: client => client.disconnect()
+        }, this.#options?.isolationPoolOptions);
+    }
+
     #legacyMode(): void {
         if (!this.#options?.legacyMode) return;
 
@@ -422,6 +427,8 @@ export default class RedisClient<
     }
 
     connect(): Promise<void> {
+        // see comment in constructor
+        this.#isolationPool ??= this.#initiateIsolationPool();
         return this.#socket.connect();
     }
 
@@ -704,6 +711,7 @@ export default class RedisClient<
     }
 
     executeIsolated<T>(fn: (client: RedisClientType<M, F, S>) => T | Promise<T>): Promise<T> {
+        if (!this.#isolationPool) return Promise.reject(new ClientClosedError());
         return this.#isolationPool.use(fn);
     }
 
@@ -802,8 +810,9 @@ export default class RedisClient<
     }
 
     async #destroyIsolationPool(): Promise<void> {
-        await this.#isolationPool.drain();
-        await this.#isolationPool.clear();
+        await this.#isolationPool!.drain();
+        await this.#isolationPool!.clear();
+        this.#isolationPool = undefined;
     }
 
     ref(): void {