diff --git a/src/aliased_buffer.h b/src/aliased_buffer.h
index fa610a97744840..0bae974af7a52c 100644
--- a/src/aliased_buffer.h
+++ b/src/aliased_buffer.h
@@ -198,9 +198,7 @@ class AliasedBuffer {
    *  Set position index to given value.
    */
   inline void SetValue(const size_t index, NativeT value) {
-#if defined(DEBUG) && DEBUG
-    CHECK_LT(index, count_);
-#endif
+    DCHECK_LT(index, count_);
     buffer_[index] = value;
   }
 
@@ -208,9 +206,7 @@ class AliasedBuffer {
    *  Get value at position index
    */
   inline const NativeT GetValue(const size_t index) const {
-#if defined(DEBUG) && DEBUG
-    CHECK_LT(index, count_);
-#endif
+    DCHECK_LT(index, count_);
     return buffer_[index];
   }
 
@@ -233,9 +229,9 @@ class AliasedBuffer {
   // Should only be used on an owning array, not one created as a sub array of
   // an owning `AliasedBuffer`.
   void reserve(size_t new_capacity) {
+    DCHECK_GE(new_capacity, count_);
+    DCHECK_EQ(byte_offset_, 0);
 #if defined(DEBUG) && DEBUG
-    CHECK_GE(new_capacity, count_);
-    CHECK_EQ(byte_offset_, 0);
     CHECK(free_buffer_);
 #endif
     const v8::HandleScope handle_scope(isolate_);
diff --git a/src/base_object-inl.h b/src/base_object-inl.h
index cce872739381cf..84c449a30814e2 100644
--- a/src/base_object-inl.h
+++ b/src/base_object-inl.h
@@ -115,8 +115,8 @@ BaseObject::MakeLazilyInitializedJSTemplate(Environment* env) {
   auto constructor = [](const v8::FunctionCallbackInfo<v8::Value>& args) {
 #ifdef DEBUG
     CHECK(args.IsConstructCall());
-    CHECK_GT(args.This()->InternalFieldCount(), 0);
 #endif
+    DCHECK_GT(args.This()->InternalFieldCount(), 0);
     args.This()->SetAlignedPointerInInternalField(0, nullptr);
   };
 
diff --git a/src/debug_utils.h b/src/debug_utils.h
index 034d8a9ab331dc..ed5e42fcbe8e6e 100644
--- a/src/debug_utils.h
+++ b/src/debug_utils.h
@@ -68,9 +68,7 @@ template <typename... Args>
 inline void FORCE_INLINE Debug(AsyncWrap* async_wrap,
                                const char* format,
                                Args&&... args) {
-#ifdef DEBUG
-  CHECK_NOT_NULL(async_wrap);
-#endif
+  DCHECK_NOT_NULL(async_wrap);
   DebugCategory cat =
       static_cast<DebugCategory>(async_wrap->provider_type());
   if (!UNLIKELY(async_wrap->env()->debug_enabled(cat)))
diff --git a/src/string_decoder.cc b/src/string_decoder.cc
index a83d6623b4b4bb..96c6baa4d815e4 100644
--- a/src/string_decoder.cc
+++ b/src/string_decoder.cc
@@ -123,11 +123,9 @@ MaybeLocal<String> StringDecoder::DecodeData(Isolate* isolate,
       body = !prepend.IsEmpty() ? prepend : String::Empty(isolate);
       prepend = Local<String>();
     } else {
-#ifdef DEBUG
       // If not, that means is no character left to finish at this point.
-      CHECK_EQ(MissingBytes(), 0);
-      CHECK_EQ(BufferedBytes(), 0);
-#endif
+      DCHECK_EQ(MissingBytes(), 0);
+      DCHECK_EQ(BufferedBytes(), 0);
 
       // See whether there is a character that we may have to cut off and
       // finish when receiving the next chunk.
@@ -136,9 +134,7 @@ MaybeLocal<String> StringDecoder::DecodeData(Isolate* isolate,
         // This means we'll need to figure out where the character to which
         // the byte belongs begins.
         for (size_t i = nread - 1; ; --i) {
-#ifdef DEBUG
-          CHECK_LT(i, nread);
-#endif
+          DCHECK_LT(i, nread);
           state_[kBufferedBytes]++;
           if ((data[i] & 0xC0) == 0x80) {
             // This byte does not start a character (a "trailing" byte).
diff --git a/src/string_search.h b/src/string_search.h
index 358a4c1b024e67..7d59d89df78329 100644
--- a/src/string_search.h
+++ b/src/string_search.h
@@ -37,9 +37,7 @@ class Vector {
 
   // Access individual vector elements - checks bounds in debug mode.
   T& operator[](size_t index) const {
-#ifdef DEBUG
-    CHECK(index < length_);
-#endif
+    DCHECK_LT(index, length_);
     return start_[is_forward_ ? index : (length_ - index - 1)];
   }