diff --git a/integration/bytes-as-base64/message.ts b/integration/bytes-as-base64/message.ts
index 11eda8f8d..7ed86903b 100644
--- a/integration/bytes-as-base64/message.ts
+++ b/integration/bytes-as-base64/message.ts
@@ -32,7 +32,7 @@ export const Message = {
 declare var self: any | undefined;
 declare var window: any | undefined;
 declare var global: any | undefined;
-var globalThis: any = (() => {
+var tsProtoGlobalThis: any = (() => {
   if (typeof globalThis !== "undefined") {
     return globalThis;
   }
@@ -49,10 +49,10 @@ var globalThis: any = (() => {
 })();
 
 function bytesFromBase64(b64: string): Uint8Array {
-  if (globalThis.Buffer) {
-    return Uint8Array.from(globalThis.Buffer.from(b64, "base64"));
+  if (tsProtoGlobalThis.Buffer) {
+    return Uint8Array.from(tsProtoGlobalThis.Buffer.from(b64, "base64"));
   } else {
-    const bin = globalThis.atob(b64);
+    const bin = tsProtoGlobalThis.atob(b64);
     const arr = new Uint8Array(bin.length);
     for (let i = 0; i < bin.length; ++i) {
       arr[i] = bin.charCodeAt(i);
@@ -62,14 +62,14 @@ function bytesFromBase64(b64: string): Uint8Array {
 }
 
 function base64FromBytes(arr: Uint8Array): string {
-  if (globalThis.Buffer) {
-    return globalThis.Buffer.from(arr).toString("base64");
+  if (tsProtoGlobalThis.Buffer) {
+    return tsProtoGlobalThis.Buffer.from(arr).toString("base64");
   } else {
     const bin: string[] = [];
     arr.forEach((byte) => {
       bin.push(String.fromCharCode(byte));
     });
-    return globalThis.btoa(bin.join(""));
+    return tsProtoGlobalThis.btoa(bin.join(""));
   }
 }
 
diff --git a/integration/bytes-node/google/protobuf/wrappers.ts b/integration/bytes-node/google/protobuf/wrappers.ts
index d1b77e648..312848ba5 100644
--- a/integration/bytes-node/google/protobuf/wrappers.ts
+++ b/integration/bytes-node/google/protobuf/wrappers.ts
@@ -521,7 +521,7 @@ export const BytesValue = {
 declare var self: any | undefined;
 declare var window: any | undefined;
 declare var global: any | undefined;
-var globalThis: any = (() => {
+var tsProtoGlobalThis: any = (() => {
   if (typeof globalThis !== "undefined") {
     return globalThis;
   }
@@ -538,10 +538,10 @@ var globalThis: any = (() => {
 })();
 
 function bytesFromBase64(b64: string): Uint8Array {
-  if (globalThis.Buffer) {
-    return Uint8Array.from(globalThis.Buffer.from(b64, "base64"));
+  if (tsProtoGlobalThis.Buffer) {
+    return Uint8Array.from(tsProtoGlobalThis.Buffer.from(b64, "base64"));
   } else {
-    const bin = globalThis.atob(b64);
+    const bin = tsProtoGlobalThis.atob(b64);
     const arr = new Uint8Array(bin.length);
     for (let i = 0; i < bin.length; ++i) {
       arr[i] = bin.charCodeAt(i);
@@ -551,14 +551,14 @@ function bytesFromBase64(b64: string): Uint8Array {
 }
 
 function base64FromBytes(arr: Uint8Array): string {
-  if (globalThis.Buffer) {
-    return globalThis.Buffer.from(arr).toString("base64");
+  if (tsProtoGlobalThis.Buffer) {
+    return tsProtoGlobalThis.Buffer.from(arr).toString("base64");
   } else {
     const bin: string[] = [];
     arr.forEach((byte) => {
       bin.push(String.fromCharCode(byte));
     });
-    return globalThis.btoa(bin.join(""));
+    return tsProtoGlobalThis.btoa(bin.join(""));
   }
 }
 
@@ -575,7 +575,7 @@ export type Exact<P, I extends P> = P extends Builtin ? P
 
 function longToNumber(long: Long): number {
   if (long.gt(Number.MAX_SAFE_INTEGER)) {
-    throw new globalThis.Error("Value is larger than Number.MAX_SAFE_INTEGER");
+    throw new tsProtoGlobalThis.Error("Value is larger than Number.MAX_SAFE_INTEGER");
   }
   return long.toNumber();
 }
diff --git a/integration/bytes-node/point.ts b/integration/bytes-node/point.ts
index ee299e099..24c353441 100644
--- a/integration/bytes-node/point.ts
+++ b/integration/bytes-node/point.ts
@@ -71,7 +71,7 @@ export const Point = {
 declare var self: any | undefined;
 declare var window: any | undefined;
 declare var global: any | undefined;
-var globalThis: any = (() => {
+var tsProtoGlobalThis: any = (() => {
   if (typeof globalThis !== "undefined") {
     return globalThis;
   }
@@ -88,10 +88,10 @@ var globalThis: any = (() => {
 })();
 
 function bytesFromBase64(b64: string): Uint8Array {
-  if (globalThis.Buffer) {
-    return Uint8Array.from(globalThis.Buffer.from(b64, "base64"));
+  if (tsProtoGlobalThis.Buffer) {
+    return Uint8Array.from(tsProtoGlobalThis.Buffer.from(b64, "base64"));
   } else {
-    const bin = globalThis.atob(b64);
+    const bin = tsProtoGlobalThis.atob(b64);
     const arr = new Uint8Array(bin.length);
     for (let i = 0; i < bin.length; ++i) {
       arr[i] = bin.charCodeAt(i);
@@ -101,14 +101,14 @@ function bytesFromBase64(b64: string): Uint8Array {
 }
 
 function base64FromBytes(arr: Uint8Array): string {
-  if (globalThis.Buffer) {
-    return globalThis.Buffer.from(arr).toString("base64");
+  if (tsProtoGlobalThis.Buffer) {
+    return tsProtoGlobalThis.Buffer.from(arr).toString("base64");
   } else {
     const bin: string[] = [];
     arr.forEach((byte) => {
       bin.push(String.fromCharCode(byte));
     });
-    return globalThis.btoa(bin.join(""));
+    return tsProtoGlobalThis.btoa(bin.join(""));
   }
 }
 
diff --git a/integration/file-suffix/google/protobuf/timestamp.pb.ts b/integration/file-suffix/google/protobuf/timestamp.pb.ts
index 5497f7183..1825e1607 100644
--- a/integration/file-suffix/google/protobuf/timestamp.pb.ts
+++ b/integration/file-suffix/google/protobuf/timestamp.pb.ts
@@ -172,7 +172,7 @@ export const Timestamp = {
 declare var self: any | undefined;
 declare var window: any | undefined;
 declare var global: any | undefined;
-var globalThis: any = (() => {
+var tsProtoGlobalThis: any = (() => {
   if (typeof globalThis !== "undefined") {
     return globalThis;
   }
@@ -201,7 +201,7 @@ export type Exact<P, I extends P> = P extends Builtin ? P
 
 function longToNumber(long: Long): number {
   if (long.gt(Number.MAX_SAFE_INTEGER)) {
-    throw new globalThis.Error("Value is larger than Number.MAX_SAFE_INTEGER");
+    throw new tsProtoGlobalThis.Error("Value is larger than Number.MAX_SAFE_INTEGER");
   }
   return long.toNumber();
 }
diff --git a/integration/grpc-js/google/protobuf/timestamp.ts b/integration/grpc-js/google/protobuf/timestamp.ts
index 5497f7183..1825e1607 100644
--- a/integration/grpc-js/google/protobuf/timestamp.ts
+++ b/integration/grpc-js/google/protobuf/timestamp.ts
@@ -172,7 +172,7 @@ export const Timestamp = {
 declare var self: any | undefined;
 declare var window: any | undefined;
 declare var global: any | undefined;
-var globalThis: any = (() => {
+var tsProtoGlobalThis: any = (() => {
   if (typeof globalThis !== "undefined") {
     return globalThis;
   }
@@ -201,7 +201,7 @@ export type Exact<P, I extends P> = P extends Builtin ? P
 
 function longToNumber(long: Long): number {
   if (long.gt(Number.MAX_SAFE_INTEGER)) {
-    throw new globalThis.Error("Value is larger than Number.MAX_SAFE_INTEGER");
+    throw new tsProtoGlobalThis.Error("Value is larger than Number.MAX_SAFE_INTEGER");
   }
   return long.toNumber();
 }
diff --git a/integration/grpc-js/google/protobuf/wrappers.ts b/integration/grpc-js/google/protobuf/wrappers.ts
index 3145298cb..901cd737e 100644
--- a/integration/grpc-js/google/protobuf/wrappers.ts
+++ b/integration/grpc-js/google/protobuf/wrappers.ts
@@ -521,7 +521,7 @@ export const BytesValue = {
 declare var self: any | undefined;
 declare var window: any | undefined;
 declare var global: any | undefined;
-var globalThis: any = (() => {
+var tsProtoGlobalThis: any = (() => {
   if (typeof globalThis !== "undefined") {
     return globalThis;
   }
@@ -538,10 +538,10 @@ var globalThis: any = (() => {
 })();
 
 function bytesFromBase64(b64: string): Uint8Array {
-  if (globalThis.Buffer) {
-    return Uint8Array.from(globalThis.Buffer.from(b64, "base64"));
+  if (tsProtoGlobalThis.Buffer) {
+    return Uint8Array.from(tsProtoGlobalThis.Buffer.from(b64, "base64"));
   } else {
-    const bin = globalThis.atob(b64);
+    const bin = tsProtoGlobalThis.atob(b64);
     const arr = new Uint8Array(bin.length);
     for (let i = 0; i < bin.length; ++i) {
       arr[i] = bin.charCodeAt(i);
@@ -551,14 +551,14 @@ function bytesFromBase64(b64: string): Uint8Array {
 }
 
 function base64FromBytes(arr: Uint8Array): string {
-  if (globalThis.Buffer) {
-    return globalThis.Buffer.from(arr).toString("base64");
+  if (tsProtoGlobalThis.Buffer) {
+    return tsProtoGlobalThis.Buffer.from(arr).toString("base64");
   } else {
     const bin: string[] = [];
     arr.forEach((byte) => {
       bin.push(String.fromCharCode(byte));
     });
-    return globalThis.btoa(bin.join(""));
+    return tsProtoGlobalThis.btoa(bin.join(""));
   }
 }
 
@@ -575,7 +575,7 @@ export type Exact<P, I extends P> = P extends Builtin ? P
 
 function longToNumber(long: Long): number {
   if (long.gt(Number.MAX_SAFE_INTEGER)) {
-    throw new globalThis.Error("Value is larger than Number.MAX_SAFE_INTEGER");
+    throw new tsProtoGlobalThis.Error("Value is larger than Number.MAX_SAFE_INTEGER");
   }
   return long.toNumber();
 }
diff --git a/integration/grpc-web-no-streaming-observable/example.ts b/integration/grpc-web-no-streaming-observable/example.ts
index 1bfdb4221..2de2723d8 100644
--- a/integration/grpc-web-no-streaming-observable/example.ts
+++ b/integration/grpc-web-no-streaming-observable/example.ts
@@ -415,6 +415,25 @@ export class GrpcWebImpl {
   }
 }
 
+declare var self: any | undefined;
+declare var window: any | undefined;
+declare var global: any | undefined;
+var tsProtoGlobalThis: any = (() => {
+  if (typeof globalThis !== "undefined") {
+    return globalThis;
+  }
+  if (typeof self !== "undefined") {
+    return self;
+  }
+  if (typeof window !== "undefined") {
+    return window;
+  }
+  if (typeof global !== "undefined") {
+    return global;
+  }
+  throw "Unable to locate global object";
+})();
+
 type Builtin = Date | Function | Uint8Array | string | number | boolean | undefined;
 
 export type DeepPartial<T> = T extends Builtin ? T
@@ -430,7 +449,7 @@ function isSet(value: any): boolean {
   return value !== null && value !== undefined;
 }
 
-export class GrpcWebError extends globalThis.Error {
+export class GrpcWebError extends tsProtoGlobalThis.Error {
   constructor(message: string, public code: grpc.Code, public metadata: grpc.Metadata) {
     super(message);
   }
diff --git a/integration/grpc-web-no-streaming/example.ts b/integration/grpc-web-no-streaming/example.ts
index 17bc4bab3..da77c277c 100644
--- a/integration/grpc-web-no-streaming/example.ts
+++ b/integration/grpc-web-no-streaming/example.ts
@@ -412,6 +412,25 @@ export class GrpcWebImpl {
   }
 }
 
+declare var self: any | undefined;
+declare var window: any | undefined;
+declare var global: any | undefined;
+var tsProtoGlobalThis: any = (() => {
+  if (typeof globalThis !== "undefined") {
+    return globalThis;
+  }
+  if (typeof self !== "undefined") {
+    return self;
+  }
+  if (typeof window !== "undefined") {
+    return window;
+  }
+  if (typeof global !== "undefined") {
+    return global;
+  }
+  throw "Unable to locate global object";
+})();
+
 type Builtin = Date | Function | Uint8Array | string | number | boolean | undefined;
 
 export type DeepPartial<T> = T extends Builtin ? T
@@ -427,7 +446,7 @@ function isSet(value: any): boolean {
   return value !== null && value !== undefined;
 }
 
-export class GrpcWebError extends globalThis.Error {
+export class GrpcWebError extends tsProtoGlobalThis.Error {
   constructor(message: string, public code: grpc.Code, public metadata: grpc.Metadata) {
     super(message);
   }
diff --git a/integration/grpc-web/example.ts b/integration/grpc-web/example.ts
index ae32731ea..b1ec8a3a5 100644
--- a/integration/grpc-web/example.ts
+++ b/integration/grpc-web/example.ts
@@ -893,6 +893,25 @@ export class GrpcWebImpl {
   }
 }
 
+declare var self: any | undefined;
+declare var window: any | undefined;
+declare var global: any | undefined;
+var tsProtoGlobalThis: any = (() => {
+  if (typeof globalThis !== "undefined") {
+    return globalThis;
+  }
+  if (typeof self !== "undefined") {
+    return self;
+  }
+  if (typeof window !== "undefined") {
+    return window;
+  }
+  if (typeof global !== "undefined") {
+    return global;
+  }
+  throw "Unable to locate global object";
+})();
+
 type Builtin = Date | Function | Uint8Array | string | number | boolean | undefined;
 
 export type DeepPartial<T> = T extends Builtin ? T
@@ -908,7 +927,7 @@ function isSet(value: any): boolean {
   return value !== null && value !== undefined;
 }
 
-export class GrpcWebError extends globalThis.Error {
+export class GrpcWebError extends tsProtoGlobalThis.Error {
   constructor(message: string, public code: grpc.Code, public metadata: grpc.Metadata) {
     super(message);
   }
diff --git a/integration/import-mapping/google/protobuf/timestamp.ts b/integration/import-mapping/google/protobuf/timestamp.ts
index 5497f7183..1825e1607 100644
--- a/integration/import-mapping/google/protobuf/timestamp.ts
+++ b/integration/import-mapping/google/protobuf/timestamp.ts
@@ -172,7 +172,7 @@ export const Timestamp = {
 declare var self: any | undefined;
 declare var window: any | undefined;
 declare var global: any | undefined;
-var globalThis: any = (() => {
+var tsProtoGlobalThis: any = (() => {
   if (typeof globalThis !== "undefined") {
     return globalThis;
   }
@@ -201,7 +201,7 @@ export type Exact<P, I extends P> = P extends Builtin ? P
 
 function longToNumber(long: Long): number {
   if (long.gt(Number.MAX_SAFE_INTEGER)) {
-    throw new globalThis.Error("Value is larger than Number.MAX_SAFE_INTEGER");
+    throw new tsProtoGlobalThis.Error("Value is larger than Number.MAX_SAFE_INTEGER");
   }
   return long.toNumber();
 }
diff --git a/integration/import-suffix/google/protobuf/timestamp.pb.ts b/integration/import-suffix/google/protobuf/timestamp.pb.ts
index 5d5da9d85..edab16743 100644
--- a/integration/import-suffix/google/protobuf/timestamp.pb.ts
+++ b/integration/import-suffix/google/protobuf/timestamp.pb.ts
@@ -172,7 +172,7 @@ export const Timestamp = {
 declare var self: any | undefined;
 declare var window: any | undefined;
 declare var global: any | undefined;
-var globalThis: any = (() => {
+var tsProtoGlobalThis: any = (() => {
   if (typeof globalThis !== "undefined") {
     return globalThis;
   }
@@ -201,7 +201,7 @@ export type Exact<P, I extends P> = P extends Builtin ? P
 
 function longToNumber(long: Long): number {
   if (long.gt(Number.MAX_SAFE_INTEGER)) {
-    throw new globalThis.Error("Value is larger than Number.MAX_SAFE_INTEGER");
+    throw new tsProtoGlobalThis.Error("Value is larger than Number.MAX_SAFE_INTEGER");
   }
   return long.toNumber();
 }
diff --git a/integration/meta-typings/google/protobuf/timestamp.ts b/integration/meta-typings/google/protobuf/timestamp.ts
index 7a575724e..872fdb6f4 100644
--- a/integration/meta-typings/google/protobuf/timestamp.ts
+++ b/integration/meta-typings/google/protobuf/timestamp.ts
@@ -272,7 +272,7 @@ export const protoMetadata: ProtoMetadata = {
 declare var self: any | undefined;
 declare var window: any | undefined;
 declare var global: any | undefined;
-var globalThis: any = (() => {
+var tsProtoGlobalThis: any = (() => {
   if (typeof globalThis !== "undefined") {
     return globalThis;
   }
@@ -290,7 +290,7 @@ var globalThis: any = (() => {
 
 function longToNumber(long: Long): number {
   if (long.gt(Number.MAX_SAFE_INTEGER)) {
-    throw new globalThis.Error("Value is larger than Number.MAX_SAFE_INTEGER");
+    throw new tsProtoGlobalThis.Error("Value is larger than Number.MAX_SAFE_INTEGER");
   }
   return long.toNumber();
 }
diff --git a/integration/meta-typings/google/protobuf/wrappers.ts b/integration/meta-typings/google/protobuf/wrappers.ts
index fd7b093af..f57ca984b 100644
--- a/integration/meta-typings/google/protobuf/wrappers.ts
+++ b/integration/meta-typings/google/protobuf/wrappers.ts
@@ -775,7 +775,7 @@ export const protoMetadata: ProtoMetadata = {
 declare var self: any | undefined;
 declare var window: any | undefined;
 declare var global: any | undefined;
-var globalThis: any = (() => {
+var tsProtoGlobalThis: any = (() => {
   if (typeof globalThis !== "undefined") {
     return globalThis;
   }
@@ -793,7 +793,7 @@ var globalThis: any = (() => {
 
 function longToNumber(long: Long): number {
   if (long.gt(Number.MAX_SAFE_INTEGER)) {
-    throw new globalThis.Error("Value is larger than Number.MAX_SAFE_INTEGER");
+    throw new tsProtoGlobalThis.Error("Value is larger than Number.MAX_SAFE_INTEGER");
   }
   return long.toNumber();
 }
diff --git a/integration/meta-typings/simple.ts b/integration/meta-typings/simple.ts
index 70dbde53a..e8cdaef83 100644
--- a/integration/meta-typings/simple.ts
+++ b/integration/meta-typings/simple.ts
@@ -2639,7 +2639,7 @@ export const protoMetadata: ProtoMetadata = {
 declare var self: any | undefined;
 declare var window: any | undefined;
 declare var global: any | undefined;
-var globalThis: any = (() => {
+var tsProtoGlobalThis: any = (() => {
   if (typeof globalThis !== "undefined") {
     return globalThis;
   }
@@ -2669,7 +2669,7 @@ function fromTimestamp(t: Timestamp): Date {
 
 function longToNumber(long: Long): number {
   if (long.gt(Number.MAX_SAFE_INTEGER)) {
-    throw new globalThis.Error("Value is larger than Number.MAX_SAFE_INTEGER");
+    throw new tsProtoGlobalThis.Error("Value is larger than Number.MAX_SAFE_INTEGER");
   }
   return long.toNumber();
 }
diff --git a/integration/nice-grpc/google/protobuf/timestamp.ts b/integration/nice-grpc/google/protobuf/timestamp.ts
index 637f54483..5893b6808 100644
--- a/integration/nice-grpc/google/protobuf/timestamp.ts
+++ b/integration/nice-grpc/google/protobuf/timestamp.ts
@@ -172,7 +172,7 @@ export const Timestamp = {
 declare var self: any | undefined;
 declare var window: any | undefined;
 declare var global: any | undefined;
-var globalThis: any = (() => {
+var tsProtoGlobalThis: any = (() => {
   if (typeof globalThis !== "undefined") {
     return globalThis;
   }
@@ -197,7 +197,7 @@ export type DeepPartial<T> = T extends Builtin ? T
 
 function longToNumber(long: Long): number {
   if (long.gt(Number.MAX_SAFE_INTEGER)) {
-    throw new globalThis.Error("Value is larger than Number.MAX_SAFE_INTEGER");
+    throw new tsProtoGlobalThis.Error("Value is larger than Number.MAX_SAFE_INTEGER");
   }
   return long.toNumber();
 }
diff --git a/integration/nice-grpc/google/protobuf/wrappers.ts b/integration/nice-grpc/google/protobuf/wrappers.ts
index 21a0c1424..9a2e58387 100644
--- a/integration/nice-grpc/google/protobuf/wrappers.ts
+++ b/integration/nice-grpc/google/protobuf/wrappers.ts
@@ -521,7 +521,7 @@ export const BytesValue = {
 declare var self: any | undefined;
 declare var window: any | undefined;
 declare var global: any | undefined;
-var globalThis: any = (() => {
+var tsProtoGlobalThis: any = (() => {
   if (typeof globalThis !== "undefined") {
     return globalThis;
   }
@@ -538,10 +538,10 @@ var globalThis: any = (() => {
 })();
 
 function bytesFromBase64(b64: string): Uint8Array {
-  if (globalThis.Buffer) {
-    return Uint8Array.from(globalThis.Buffer.from(b64, "base64"));
+  if (tsProtoGlobalThis.Buffer) {
+    return Uint8Array.from(tsProtoGlobalThis.Buffer.from(b64, "base64"));
   } else {
-    const bin = globalThis.atob(b64);
+    const bin = tsProtoGlobalThis.atob(b64);
     const arr = new Uint8Array(bin.length);
     for (let i = 0; i < bin.length; ++i) {
       arr[i] = bin.charCodeAt(i);
@@ -551,14 +551,14 @@ function bytesFromBase64(b64: string): Uint8Array {
 }
 
 function base64FromBytes(arr: Uint8Array): string {
-  if (globalThis.Buffer) {
-    return globalThis.Buffer.from(arr).toString("base64");
+  if (tsProtoGlobalThis.Buffer) {
+    return tsProtoGlobalThis.Buffer.from(arr).toString("base64");
   } else {
     const bin: string[] = [];
     arr.forEach((byte) => {
       bin.push(String.fromCharCode(byte));
     });
-    return globalThis.btoa(bin.join(""));
+    return tsProtoGlobalThis.btoa(bin.join(""));
   }
 }
 
@@ -571,7 +571,7 @@ export type DeepPartial<T> = T extends Builtin ? T
 
 function longToNumber(long: Long): number {
   if (long.gt(Number.MAX_SAFE_INTEGER)) {
-    throw new globalThis.Error("Value is larger than Number.MAX_SAFE_INTEGER");
+    throw new tsProtoGlobalThis.Error("Value is larger than Number.MAX_SAFE_INTEGER");
   }
   return long.toNumber();
 }
diff --git a/integration/oneof-properties/oneof.ts b/integration/oneof-properties/oneof.ts
index d371b089d..b2c4cb4af 100644
--- a/integration/oneof-properties/oneof.ts
+++ b/integration/oneof-properties/oneof.ts
@@ -282,7 +282,7 @@ export const PleaseChoose_Submessage = {
 declare var self: any | undefined;
 declare var window: any | undefined;
 declare var global: any | undefined;
-var globalThis: any = (() => {
+var tsProtoGlobalThis: any = (() => {
   if (typeof globalThis !== "undefined") {
     return globalThis;
   }
@@ -299,10 +299,10 @@ var globalThis: any = (() => {
 })();
 
 function bytesFromBase64(b64: string): Uint8Array {
-  if (globalThis.Buffer) {
-    return Uint8Array.from(globalThis.Buffer.from(b64, "base64"));
+  if (tsProtoGlobalThis.Buffer) {
+    return Uint8Array.from(tsProtoGlobalThis.Buffer.from(b64, "base64"));
   } else {
-    const bin = globalThis.atob(b64);
+    const bin = tsProtoGlobalThis.atob(b64);
     const arr = new Uint8Array(bin.length);
     for (let i = 0; i < bin.length; ++i) {
       arr[i] = bin.charCodeAt(i);
@@ -312,14 +312,14 @@ function bytesFromBase64(b64: string): Uint8Array {
 }
 
 function base64FromBytes(arr: Uint8Array): string {
-  if (globalThis.Buffer) {
-    return globalThis.Buffer.from(arr).toString("base64");
+  if (tsProtoGlobalThis.Buffer) {
+    return tsProtoGlobalThis.Buffer.from(arr).toString("base64");
   } else {
     const bin: string[] = [];
     arr.forEach((byte) => {
       bin.push(String.fromCharCode(byte));
     });
-    return globalThis.btoa(bin.join(""));
+    return tsProtoGlobalThis.btoa(bin.join(""));
   }
 }
 
diff --git a/integration/oneof-unions/oneof.ts b/integration/oneof-unions/oneof.ts
index e89ecca74..7fbacfe1a 100644
--- a/integration/oneof-unions/oneof.ts
+++ b/integration/oneof-unions/oneof.ts
@@ -383,7 +383,7 @@ export const SimpleButOptional = {
 declare var self: any | undefined;
 declare var window: any | undefined;
 declare var global: any | undefined;
-var globalThis: any = (() => {
+var tsProtoGlobalThis: any = (() => {
   if (typeof globalThis !== "undefined") {
     return globalThis;
   }
@@ -400,10 +400,10 @@ var globalThis: any = (() => {
 })();
 
 function bytesFromBase64(b64: string): Uint8Array {
-  if (globalThis.Buffer) {
-    return Uint8Array.from(globalThis.Buffer.from(b64, "base64"));
+  if (tsProtoGlobalThis.Buffer) {
+    return Uint8Array.from(tsProtoGlobalThis.Buffer.from(b64, "base64"));
   } else {
-    const bin = globalThis.atob(b64);
+    const bin = tsProtoGlobalThis.atob(b64);
     const arr = new Uint8Array(bin.length);
     for (let i = 0; i < bin.length; ++i) {
       arr[i] = bin.charCodeAt(i);
@@ -413,14 +413,14 @@ function bytesFromBase64(b64: string): Uint8Array {
 }
 
 function base64FromBytes(arr: Uint8Array): string {
-  if (globalThis.Buffer) {
-    return globalThis.Buffer.from(arr).toString("base64");
+  if (tsProtoGlobalThis.Buffer) {
+    return tsProtoGlobalThis.Buffer.from(arr).toString("base64");
   } else {
     const bin: string[] = [];
     arr.forEach((byte) => {
       bin.push(String.fromCharCode(byte));
     });
-    return globalThis.btoa(bin.join(""));
+    return tsProtoGlobalThis.btoa(bin.join(""));
   }
 }
 
diff --git a/integration/options/google/protobuf/descriptor.ts b/integration/options/google/protobuf/descriptor.ts
index 919f4e5b9..6469a46d9 100644
--- a/integration/options/google/protobuf/descriptor.ts
+++ b/integration/options/google/protobuf/descriptor.ts
@@ -5243,7 +5243,7 @@ export const protoMetadata: ProtoMetadata = {
 declare var self: any | undefined;
 declare var window: any | undefined;
 declare var global: any | undefined;
-var globalThis: any = (() => {
+var tsProtoGlobalThis: any = (() => {
   if (typeof globalThis !== "undefined") {
     return globalThis;
   }
@@ -5261,7 +5261,7 @@ var globalThis: any = (() => {
 
 function longToNumber(long: Long): number {
   if (long.gt(Number.MAX_SAFE_INTEGER)) {
-    throw new globalThis.Error("Value is larger than Number.MAX_SAFE_INTEGER");
+    throw new tsProtoGlobalThis.Error("Value is larger than Number.MAX_SAFE_INTEGER");
   }
   return long.toNumber();
 }
diff --git a/integration/simple-esmodule-interop/simple.ts b/integration/simple-esmodule-interop/simple.ts
index 42cb50832..8adfceb53 100644
--- a/integration/simple-esmodule-interop/simple.ts
+++ b/integration/simple-esmodule-interop/simple.ts
@@ -243,7 +243,7 @@ export const Numbers = {
 declare var self: any | undefined;
 declare var window: any | undefined;
 declare var global: any | undefined;
-var globalThis: any = (() => {
+var tsProtoGlobalThis: any = (() => {
   if (typeof globalThis !== "undefined") {
     return globalThis;
   }
@@ -272,7 +272,7 @@ export type Exact<P, I extends P> = P extends Builtin ? P
 
 function longToNumber(long: Long): number {
   if (long.gt(Number.MAX_SAFE_INTEGER)) {
-    throw new globalThis.Error("Value is larger than Number.MAX_SAFE_INTEGER");
+    throw new tsProtoGlobalThis.Error("Value is larger than Number.MAX_SAFE_INTEGER");
   }
   return long.toNumber();
 }
diff --git a/integration/simple-json-name/google/protobuf/timestamp.ts b/integration/simple-json-name/google/protobuf/timestamp.ts
index 5497f7183..1825e1607 100644
--- a/integration/simple-json-name/google/protobuf/timestamp.ts
+++ b/integration/simple-json-name/google/protobuf/timestamp.ts
@@ -172,7 +172,7 @@ export const Timestamp = {
 declare var self: any | undefined;
 declare var window: any | undefined;
 declare var global: any | undefined;
-var globalThis: any = (() => {
+var tsProtoGlobalThis: any = (() => {
   if (typeof globalThis !== "undefined") {
     return globalThis;
   }
@@ -201,7 +201,7 @@ export type Exact<P, I extends P> = P extends Builtin ? P
 
 function longToNumber(long: Long): number {
   if (long.gt(Number.MAX_SAFE_INTEGER)) {
-    throw new globalThis.Error("Value is larger than Number.MAX_SAFE_INTEGER");
+    throw new tsProtoGlobalThis.Error("Value is larger than Number.MAX_SAFE_INTEGER");
   }
   return long.toNumber();
 }
diff --git a/integration/simple-long-string/google/protobuf/wrappers.ts b/integration/simple-long-string/google/protobuf/wrappers.ts
index 9deb01d20..2029208a1 100644
--- a/integration/simple-long-string/google/protobuf/wrappers.ts
+++ b/integration/simple-long-string/google/protobuf/wrappers.ts
@@ -521,7 +521,7 @@ export const BytesValue = {
 declare var self: any | undefined;
 declare var window: any | undefined;
 declare var global: any | undefined;
-var globalThis: any = (() => {
+var tsProtoGlobalThis: any = (() => {
   if (typeof globalThis !== "undefined") {
     return globalThis;
   }
@@ -538,10 +538,10 @@ var globalThis: any = (() => {
 })();
 
 function bytesFromBase64(b64: string): Uint8Array {
-  if (globalThis.Buffer) {
-    return Uint8Array.from(globalThis.Buffer.from(b64, "base64"));
+  if (tsProtoGlobalThis.Buffer) {
+    return Uint8Array.from(tsProtoGlobalThis.Buffer.from(b64, "base64"));
   } else {
-    const bin = globalThis.atob(b64);
+    const bin = tsProtoGlobalThis.atob(b64);
     const arr = new Uint8Array(bin.length);
     for (let i = 0; i < bin.length; ++i) {
       arr[i] = bin.charCodeAt(i);
@@ -551,14 +551,14 @@ function bytesFromBase64(b64: string): Uint8Array {
 }
 
 function base64FromBytes(arr: Uint8Array): string {
-  if (globalThis.Buffer) {
-    return globalThis.Buffer.from(arr).toString("base64");
+  if (tsProtoGlobalThis.Buffer) {
+    return tsProtoGlobalThis.Buffer.from(arr).toString("base64");
   } else {
     const bin: string[] = [];
     arr.forEach((byte) => {
       bin.push(String.fromCharCode(byte));
     });
-    return globalThis.btoa(bin.join(""));
+    return tsProtoGlobalThis.btoa(bin.join(""));
   }
 }
 
diff --git a/integration/simple-long/google/protobuf/wrappers.ts b/integration/simple-long/google/protobuf/wrappers.ts
index c7b5789ab..eaf84d7a0 100644
--- a/integration/simple-long/google/protobuf/wrappers.ts
+++ b/integration/simple-long/google/protobuf/wrappers.ts
@@ -521,7 +521,7 @@ export const BytesValue = {
 declare var self: any | undefined;
 declare var window: any | undefined;
 declare var global: any | undefined;
-var globalThis: any = (() => {
+var tsProtoGlobalThis: any = (() => {
   if (typeof globalThis !== "undefined") {
     return globalThis;
   }
@@ -538,10 +538,10 @@ var globalThis: any = (() => {
 })();
 
 function bytesFromBase64(b64: string): Uint8Array {
-  if (globalThis.Buffer) {
-    return Uint8Array.from(globalThis.Buffer.from(b64, "base64"));
+  if (tsProtoGlobalThis.Buffer) {
+    return Uint8Array.from(tsProtoGlobalThis.Buffer.from(b64, "base64"));
   } else {
-    const bin = globalThis.atob(b64);
+    const bin = tsProtoGlobalThis.atob(b64);
     const arr = new Uint8Array(bin.length);
     for (let i = 0; i < bin.length; ++i) {
       arr[i] = bin.charCodeAt(i);
@@ -551,14 +551,14 @@ function bytesFromBase64(b64: string): Uint8Array {
 }
 
 function base64FromBytes(arr: Uint8Array): string {
-  if (globalThis.Buffer) {
-    return globalThis.Buffer.from(arr).toString("base64");
+  if (tsProtoGlobalThis.Buffer) {
+    return tsProtoGlobalThis.Buffer.from(arr).toString("base64");
   } else {
     const bin: string[] = [];
     arr.forEach((byte) => {
       bin.push(String.fromCharCode(byte));
     });
-    return globalThis.btoa(bin.join(""));
+    return tsProtoGlobalThis.btoa(bin.join(""));
   }
 }
 
diff --git a/integration/simple-optionals/google/protobuf/timestamp.ts b/integration/simple-optionals/google/protobuf/timestamp.ts
index 5497f7183..1825e1607 100644
--- a/integration/simple-optionals/google/protobuf/timestamp.ts
+++ b/integration/simple-optionals/google/protobuf/timestamp.ts
@@ -172,7 +172,7 @@ export const Timestamp = {
 declare var self: any | undefined;
 declare var window: any | undefined;
 declare var global: any | undefined;
-var globalThis: any = (() => {
+var tsProtoGlobalThis: any = (() => {
   if (typeof globalThis !== "undefined") {
     return globalThis;
   }
@@ -201,7 +201,7 @@ export type Exact<P, I extends P> = P extends Builtin ? P
 
 function longToNumber(long: Long): number {
   if (long.gt(Number.MAX_SAFE_INTEGER)) {
-    throw new globalThis.Error("Value is larger than Number.MAX_SAFE_INTEGER");
+    throw new tsProtoGlobalThis.Error("Value is larger than Number.MAX_SAFE_INTEGER");
   }
   return long.toNumber();
 }
diff --git a/integration/simple-optionals/google/protobuf/wrappers.ts b/integration/simple-optionals/google/protobuf/wrappers.ts
index 3145298cb..901cd737e 100644
--- a/integration/simple-optionals/google/protobuf/wrappers.ts
+++ b/integration/simple-optionals/google/protobuf/wrappers.ts
@@ -521,7 +521,7 @@ export const BytesValue = {
 declare var self: any | undefined;
 declare var window: any | undefined;
 declare var global: any | undefined;
-var globalThis: any = (() => {
+var tsProtoGlobalThis: any = (() => {
   if (typeof globalThis !== "undefined") {
     return globalThis;
   }
@@ -538,10 +538,10 @@ var globalThis: any = (() => {
 })();
 
 function bytesFromBase64(b64: string): Uint8Array {
-  if (globalThis.Buffer) {
-    return Uint8Array.from(globalThis.Buffer.from(b64, "base64"));
+  if (tsProtoGlobalThis.Buffer) {
+    return Uint8Array.from(tsProtoGlobalThis.Buffer.from(b64, "base64"));
   } else {
-    const bin = globalThis.atob(b64);
+    const bin = tsProtoGlobalThis.atob(b64);
     const arr = new Uint8Array(bin.length);
     for (let i = 0; i < bin.length; ++i) {
       arr[i] = bin.charCodeAt(i);
@@ -551,14 +551,14 @@ function bytesFromBase64(b64: string): Uint8Array {
 }
 
 function base64FromBytes(arr: Uint8Array): string {
-  if (globalThis.Buffer) {
-    return globalThis.Buffer.from(arr).toString("base64");
+  if (tsProtoGlobalThis.Buffer) {
+    return tsProtoGlobalThis.Buffer.from(arr).toString("base64");
   } else {
     const bin: string[] = [];
     arr.forEach((byte) => {
       bin.push(String.fromCharCode(byte));
     });
-    return globalThis.btoa(bin.join(""));
+    return tsProtoGlobalThis.btoa(bin.join(""));
   }
 }
 
@@ -575,7 +575,7 @@ export type Exact<P, I extends P> = P extends Builtin ? P
 
 function longToNumber(long: Long): number {
   if (long.gt(Number.MAX_SAFE_INTEGER)) {
-    throw new globalThis.Error("Value is larger than Number.MAX_SAFE_INTEGER");
+    throw new tsProtoGlobalThis.Error("Value is larger than Number.MAX_SAFE_INTEGER");
   }
   return long.toNumber();
 }
diff --git a/integration/simple-optionals/simple.ts b/integration/simple-optionals/simple.ts
index d3e4dfd82..ec5c85c95 100644
--- a/integration/simple-optionals/simple.ts
+++ b/integration/simple-optionals/simple.ts
@@ -1570,7 +1570,7 @@ interface Rpc {
 declare var self: any | undefined;
 declare var window: any | undefined;
 declare var global: any | undefined;
-var globalThis: any = (() => {
+var tsProtoGlobalThis: any = (() => {
   if (typeof globalThis !== "undefined") {
     return globalThis;
   }
@@ -1621,7 +1621,7 @@ function fromJsonTimestamp(o: any): Date {
 
 function longToNumber(long: Long): number {
   if (long.gt(Number.MAX_SAFE_INTEGER)) {
-    throw new globalThis.Error("Value is larger than Number.MAX_SAFE_INTEGER");
+    throw new tsProtoGlobalThis.Error("Value is larger than Number.MAX_SAFE_INTEGER");
   }
   return long.toNumber();
 }
diff --git a/integration/simple-prototype-defaults/google/protobuf/timestamp.ts b/integration/simple-prototype-defaults/google/protobuf/timestamp.ts
index fb745da37..92b995c77 100644
--- a/integration/simple-prototype-defaults/google/protobuf/timestamp.ts
+++ b/integration/simple-prototype-defaults/google/protobuf/timestamp.ts
@@ -172,7 +172,7 @@ export const Timestamp = {
 declare var self: any | undefined;
 declare var window: any | undefined;
 declare var global: any | undefined;
-var globalThis: any = (() => {
+var tsProtoGlobalThis: any = (() => {
   if (typeof globalThis !== "undefined") {
     return globalThis;
   }
@@ -201,7 +201,7 @@ export type Exact<P, I extends P> = P extends Builtin ? P
 
 function longToNumber(long: Long): number {
   if (long.gt(Number.MAX_SAFE_INTEGER)) {
-    throw new globalThis.Error("Value is larger than Number.MAX_SAFE_INTEGER");
+    throw new tsProtoGlobalThis.Error("Value is larger than Number.MAX_SAFE_INTEGER");
   }
   return long.toNumber();
 }
diff --git a/integration/simple-prototype-defaults/google/protobuf/wrappers.ts b/integration/simple-prototype-defaults/google/protobuf/wrappers.ts
index e6fb1977d..607c1bcce 100644
--- a/integration/simple-prototype-defaults/google/protobuf/wrappers.ts
+++ b/integration/simple-prototype-defaults/google/protobuf/wrappers.ts
@@ -521,7 +521,7 @@ export const BytesValue = {
 declare var self: any | undefined;
 declare var window: any | undefined;
 declare var global: any | undefined;
-var globalThis: any = (() => {
+var tsProtoGlobalThis: any = (() => {
   if (typeof globalThis !== "undefined") {
     return globalThis;
   }
@@ -538,10 +538,10 @@ var globalThis: any = (() => {
 })();
 
 function bytesFromBase64(b64: string): Uint8Array {
-  if (globalThis.Buffer) {
-    return Uint8Array.from(globalThis.Buffer.from(b64, "base64"));
+  if (tsProtoGlobalThis.Buffer) {
+    return Uint8Array.from(tsProtoGlobalThis.Buffer.from(b64, "base64"));
   } else {
-    const bin = globalThis.atob(b64);
+    const bin = tsProtoGlobalThis.atob(b64);
     const arr = new Uint8Array(bin.length);
     for (let i = 0; i < bin.length; ++i) {
       arr[i] = bin.charCodeAt(i);
@@ -551,14 +551,14 @@ function bytesFromBase64(b64: string): Uint8Array {
 }
 
 function base64FromBytes(arr: Uint8Array): string {
-  if (globalThis.Buffer) {
-    return globalThis.Buffer.from(arr).toString("base64");
+  if (tsProtoGlobalThis.Buffer) {
+    return tsProtoGlobalThis.Buffer.from(arr).toString("base64");
   } else {
     const bin: string[] = [];
     arr.forEach((byte) => {
       bin.push(String.fromCharCode(byte));
     });
-    return globalThis.btoa(bin.join(""));
+    return tsProtoGlobalThis.btoa(bin.join(""));
   }
 }
 
@@ -575,7 +575,7 @@ export type Exact<P, I extends P> = P extends Builtin ? P
 
 function longToNumber(long: Long): number {
   if (long.gt(Number.MAX_SAFE_INTEGER)) {
-    throw new globalThis.Error("Value is larger than Number.MAX_SAFE_INTEGER");
+    throw new tsProtoGlobalThis.Error("Value is larger than Number.MAX_SAFE_INTEGER");
   }
   return long.toNumber();
 }
diff --git a/integration/simple-prototype-defaults/simple.ts b/integration/simple-prototype-defaults/simple.ts
index 6671674e5..79486a125 100644
--- a/integration/simple-prototype-defaults/simple.ts
+++ b/integration/simple-prototype-defaults/simple.ts
@@ -2347,7 +2347,7 @@ interface Rpc {
 declare var self: any | undefined;
 declare var window: any | undefined;
 declare var global: any | undefined;
-var globalThis: any = (() => {
+var tsProtoGlobalThis: any = (() => {
   if (typeof globalThis !== "undefined") {
     return globalThis;
   }
@@ -2364,10 +2364,10 @@ var globalThis: any = (() => {
 })();
 
 function bytesFromBase64(b64: string): Uint8Array {
-  if (globalThis.Buffer) {
-    return Uint8Array.from(globalThis.Buffer.from(b64, "base64"));
+  if (tsProtoGlobalThis.Buffer) {
+    return Uint8Array.from(tsProtoGlobalThis.Buffer.from(b64, "base64"));
   } else {
-    const bin = globalThis.atob(b64);
+    const bin = tsProtoGlobalThis.atob(b64);
     const arr = new Uint8Array(bin.length);
     for (let i = 0; i < bin.length; ++i) {
       arr[i] = bin.charCodeAt(i);
@@ -2377,14 +2377,14 @@ function bytesFromBase64(b64: string): Uint8Array {
 }
 
 function base64FromBytes(arr: Uint8Array): string {
-  if (globalThis.Buffer) {
-    return globalThis.Buffer.from(arr).toString("base64");
+  if (tsProtoGlobalThis.Buffer) {
+    return tsProtoGlobalThis.Buffer.from(arr).toString("base64");
   } else {
     const bin: string[] = [];
     arr.forEach((byte) => {
       bin.push(String.fromCharCode(byte));
     });
-    return globalThis.btoa(bin.join(""));
+    return tsProtoGlobalThis.btoa(bin.join(""));
   }
 }
 
@@ -2423,7 +2423,7 @@ function fromJsonTimestamp(o: any): Date {
 
 function longToNumber(long: Long): number {
   if (long.gt(Number.MAX_SAFE_INTEGER)) {
-    throw new globalThis.Error("Value is larger than Number.MAX_SAFE_INTEGER");
+    throw new tsProtoGlobalThis.Error("Value is larger than Number.MAX_SAFE_INTEGER");
   }
   return long.toNumber();
 }
diff --git a/integration/simple-snake/google/protobuf/timestamp.ts b/integration/simple-snake/google/protobuf/timestamp.ts
index 5497f7183..1825e1607 100644
--- a/integration/simple-snake/google/protobuf/timestamp.ts
+++ b/integration/simple-snake/google/protobuf/timestamp.ts
@@ -172,7 +172,7 @@ export const Timestamp = {
 declare var self: any | undefined;
 declare var window: any | undefined;
 declare var global: any | undefined;
-var globalThis: any = (() => {
+var tsProtoGlobalThis: any = (() => {
   if (typeof globalThis !== "undefined") {
     return globalThis;
   }
@@ -201,7 +201,7 @@ export type Exact<P, I extends P> = P extends Builtin ? P
 
 function longToNumber(long: Long): number {
   if (long.gt(Number.MAX_SAFE_INTEGER)) {
-    throw new globalThis.Error("Value is larger than Number.MAX_SAFE_INTEGER");
+    throw new tsProtoGlobalThis.Error("Value is larger than Number.MAX_SAFE_INTEGER");
   }
   return long.toNumber();
 }
diff --git a/integration/simple-snake/google/protobuf/wrappers.ts b/integration/simple-snake/google/protobuf/wrappers.ts
index 3145298cb..901cd737e 100644
--- a/integration/simple-snake/google/protobuf/wrappers.ts
+++ b/integration/simple-snake/google/protobuf/wrappers.ts
@@ -521,7 +521,7 @@ export const BytesValue = {
 declare var self: any | undefined;
 declare var window: any | undefined;
 declare var global: any | undefined;
-var globalThis: any = (() => {
+var tsProtoGlobalThis: any = (() => {
   if (typeof globalThis !== "undefined") {
     return globalThis;
   }
@@ -538,10 +538,10 @@ var globalThis: any = (() => {
 })();
 
 function bytesFromBase64(b64: string): Uint8Array {
-  if (globalThis.Buffer) {
-    return Uint8Array.from(globalThis.Buffer.from(b64, "base64"));
+  if (tsProtoGlobalThis.Buffer) {
+    return Uint8Array.from(tsProtoGlobalThis.Buffer.from(b64, "base64"));
   } else {
-    const bin = globalThis.atob(b64);
+    const bin = tsProtoGlobalThis.atob(b64);
     const arr = new Uint8Array(bin.length);
     for (let i = 0; i < bin.length; ++i) {
       arr[i] = bin.charCodeAt(i);
@@ -551,14 +551,14 @@ function bytesFromBase64(b64: string): Uint8Array {
 }
 
 function base64FromBytes(arr: Uint8Array): string {
-  if (globalThis.Buffer) {
-    return globalThis.Buffer.from(arr).toString("base64");
+  if (tsProtoGlobalThis.Buffer) {
+    return tsProtoGlobalThis.Buffer.from(arr).toString("base64");
   } else {
     const bin: string[] = [];
     arr.forEach((byte) => {
       bin.push(String.fromCharCode(byte));
     });
-    return globalThis.btoa(bin.join(""));
+    return tsProtoGlobalThis.btoa(bin.join(""));
   }
 }
 
@@ -575,7 +575,7 @@ export type Exact<P, I extends P> = P extends Builtin ? P
 
 function longToNumber(long: Long): number {
   if (long.gt(Number.MAX_SAFE_INTEGER)) {
-    throw new globalThis.Error("Value is larger than Number.MAX_SAFE_INTEGER");
+    throw new tsProtoGlobalThis.Error("Value is larger than Number.MAX_SAFE_INTEGER");
   }
   return long.toNumber();
 }
diff --git a/integration/simple-snake/simple.ts b/integration/simple-snake/simple.ts
index 5d416272c..b7fbc7d77 100644
--- a/integration/simple-snake/simple.ts
+++ b/integration/simple-snake/simple.ts
@@ -1622,7 +1622,7 @@ interface Rpc {
 declare var self: any | undefined;
 declare var window: any | undefined;
 declare var global: any | undefined;
-var globalThis: any = (() => {
+var tsProtoGlobalThis: any = (() => {
   if (typeof globalThis !== "undefined") {
     return globalThis;
   }
@@ -1673,7 +1673,7 @@ function fromJsonTimestamp(o: any): Date {
 
 function longToNumber(long: Long): number {
   if (long.gt(Number.MAX_SAFE_INTEGER)) {
-    throw new globalThis.Error("Value is larger than Number.MAX_SAFE_INTEGER");
+    throw new tsProtoGlobalThis.Error("Value is larger than Number.MAX_SAFE_INTEGER");
   }
   return long.toNumber();
 }
diff --git a/integration/simple-unrecognized-enum/google/protobuf/timestamp.ts b/integration/simple-unrecognized-enum/google/protobuf/timestamp.ts
index 5497f7183..1825e1607 100644
--- a/integration/simple-unrecognized-enum/google/protobuf/timestamp.ts
+++ b/integration/simple-unrecognized-enum/google/protobuf/timestamp.ts
@@ -172,7 +172,7 @@ export const Timestamp = {
 declare var self: any | undefined;
 declare var window: any | undefined;
 declare var global: any | undefined;
-var globalThis: any = (() => {
+var tsProtoGlobalThis: any = (() => {
   if (typeof globalThis !== "undefined") {
     return globalThis;
   }
@@ -201,7 +201,7 @@ export type Exact<P, I extends P> = P extends Builtin ? P
 
 function longToNumber(long: Long): number {
   if (long.gt(Number.MAX_SAFE_INTEGER)) {
-    throw new globalThis.Error("Value is larger than Number.MAX_SAFE_INTEGER");
+    throw new tsProtoGlobalThis.Error("Value is larger than Number.MAX_SAFE_INTEGER");
   }
   return long.toNumber();
 }
diff --git a/integration/simple-unrecognized-enum/google/protobuf/wrappers.ts b/integration/simple-unrecognized-enum/google/protobuf/wrappers.ts
index 3145298cb..901cd737e 100644
--- a/integration/simple-unrecognized-enum/google/protobuf/wrappers.ts
+++ b/integration/simple-unrecognized-enum/google/protobuf/wrappers.ts
@@ -521,7 +521,7 @@ export const BytesValue = {
 declare var self: any | undefined;
 declare var window: any | undefined;
 declare var global: any | undefined;
-var globalThis: any = (() => {
+var tsProtoGlobalThis: any = (() => {
   if (typeof globalThis !== "undefined") {
     return globalThis;
   }
@@ -538,10 +538,10 @@ var globalThis: any = (() => {
 })();
 
 function bytesFromBase64(b64: string): Uint8Array {
-  if (globalThis.Buffer) {
-    return Uint8Array.from(globalThis.Buffer.from(b64, "base64"));
+  if (tsProtoGlobalThis.Buffer) {
+    return Uint8Array.from(tsProtoGlobalThis.Buffer.from(b64, "base64"));
   } else {
-    const bin = globalThis.atob(b64);
+    const bin = tsProtoGlobalThis.atob(b64);
     const arr = new Uint8Array(bin.length);
     for (let i = 0; i < bin.length; ++i) {
       arr[i] = bin.charCodeAt(i);
@@ -551,14 +551,14 @@ function bytesFromBase64(b64: string): Uint8Array {
 }
 
 function base64FromBytes(arr: Uint8Array): string {
-  if (globalThis.Buffer) {
-    return globalThis.Buffer.from(arr).toString("base64");
+  if (tsProtoGlobalThis.Buffer) {
+    return tsProtoGlobalThis.Buffer.from(arr).toString("base64");
   } else {
     const bin: string[] = [];
     arr.forEach((byte) => {
       bin.push(String.fromCharCode(byte));
     });
-    return globalThis.btoa(bin.join(""));
+    return tsProtoGlobalThis.btoa(bin.join(""));
   }
 }
 
@@ -575,7 +575,7 @@ export type Exact<P, I extends P> = P extends Builtin ? P
 
 function longToNumber(long: Long): number {
   if (long.gt(Number.MAX_SAFE_INTEGER)) {
-    throw new globalThis.Error("Value is larger than Number.MAX_SAFE_INTEGER");
+    throw new tsProtoGlobalThis.Error("Value is larger than Number.MAX_SAFE_INTEGER");
   }
   return long.toNumber();
 }
diff --git a/integration/simple-unrecognized-enum/simple.ts b/integration/simple-unrecognized-enum/simple.ts
index e0a1ad32a..73cc1e711 100644
--- a/integration/simple-unrecognized-enum/simple.ts
+++ b/integration/simple-unrecognized-enum/simple.ts
@@ -30,7 +30,7 @@ export function stateEnumFromJSON(object: any): StateEnum {
     case "OFF":
       return StateEnum.OFF;
     default:
-      throw new globalThis.Error("Unrecognized enum value " + object + " for enum StateEnum");
+      throw new tsProtoGlobalThis.Error("Unrecognized enum value " + object + " for enum StateEnum");
   }
 }
 
@@ -43,7 +43,7 @@ export function stateEnumToJSON(object: StateEnum): string {
     case StateEnum.OFF:
       return "OFF";
     default:
-      throw new globalThis.Error("Unrecognized enum value " + object + " for enum StateEnum");
+      throw new tsProtoGlobalThis.Error("Unrecognized enum value " + object + " for enum StateEnum");
   }
 }
 
@@ -88,7 +88,7 @@ export function child_TypeFromJSON(object: any): Child_Type {
     case "BAD":
       return Child_Type.BAD;
     default:
-      throw new globalThis.Error("Unrecognized enum value " + object + " for enum Child_Type");
+      throw new tsProtoGlobalThis.Error("Unrecognized enum value " + object + " for enum Child_Type");
   }
 }
 
@@ -101,7 +101,7 @@ export function child_TypeToJSON(object: Child_Type): string {
     case Child_Type.BAD:
       return "BAD";
     default:
-      throw new globalThis.Error("Unrecognized enum value " + object + " for enum Child_Type");
+      throw new tsProtoGlobalThis.Error("Unrecognized enum value " + object + " for enum Child_Type");
   }
 }
 
@@ -129,7 +129,7 @@ export function nested_InnerEnumFromJSON(object: any): Nested_InnerEnum {
     case "BAD":
       return Nested_InnerEnum.BAD;
     default:
-      throw new globalThis.Error("Unrecognized enum value " + object + " for enum Nested_InnerEnum");
+      throw new tsProtoGlobalThis.Error("Unrecognized enum value " + object + " for enum Nested_InnerEnum");
   }
 }
 
@@ -142,7 +142,7 @@ export function nested_InnerEnumToJSON(object: Nested_InnerEnum): string {
     case Nested_InnerEnum.BAD:
       return "BAD";
     default:
-      throw new globalThis.Error("Unrecognized enum value " + object + " for enum Nested_InnerEnum");
+      throw new tsProtoGlobalThis.Error("Unrecognized enum value " + object + " for enum Nested_InnerEnum");
   }
 }
 
@@ -1558,7 +1558,7 @@ interface Rpc {
 declare var self: any | undefined;
 declare var window: any | undefined;
 declare var global: any | undefined;
-var globalThis: any = (() => {
+var tsProtoGlobalThis: any = (() => {
   if (typeof globalThis !== "undefined") {
     return globalThis;
   }
@@ -1609,7 +1609,7 @@ function fromJsonTimestamp(o: any): Date {
 
 function longToNumber(long: Long): number {
   if (long.gt(Number.MAX_SAFE_INTEGER)) {
-    throw new globalThis.Error("Value is larger than Number.MAX_SAFE_INTEGER");
+    throw new tsProtoGlobalThis.Error("Value is larger than Number.MAX_SAFE_INTEGER");
   }
   return long.toNumber();
 }
diff --git a/integration/simple/google/protobuf/timestamp.ts b/integration/simple/google/protobuf/timestamp.ts
index 5497f7183..1825e1607 100644
--- a/integration/simple/google/protobuf/timestamp.ts
+++ b/integration/simple/google/protobuf/timestamp.ts
@@ -172,7 +172,7 @@ export const Timestamp = {
 declare var self: any | undefined;
 declare var window: any | undefined;
 declare var global: any | undefined;
-var globalThis: any = (() => {
+var tsProtoGlobalThis: any = (() => {
   if (typeof globalThis !== "undefined") {
     return globalThis;
   }
@@ -201,7 +201,7 @@ export type Exact<P, I extends P> = P extends Builtin ? P
 
 function longToNumber(long: Long): number {
   if (long.gt(Number.MAX_SAFE_INTEGER)) {
-    throw new globalThis.Error("Value is larger than Number.MAX_SAFE_INTEGER");
+    throw new tsProtoGlobalThis.Error("Value is larger than Number.MAX_SAFE_INTEGER");
   }
   return long.toNumber();
 }
diff --git a/integration/simple/google/protobuf/wrappers.ts b/integration/simple/google/protobuf/wrappers.ts
index 3145298cb..901cd737e 100644
--- a/integration/simple/google/protobuf/wrappers.ts
+++ b/integration/simple/google/protobuf/wrappers.ts
@@ -521,7 +521,7 @@ export const BytesValue = {
 declare var self: any | undefined;
 declare var window: any | undefined;
 declare var global: any | undefined;
-var globalThis: any = (() => {
+var tsProtoGlobalThis: any = (() => {
   if (typeof globalThis !== "undefined") {
     return globalThis;
   }
@@ -538,10 +538,10 @@ var globalThis: any = (() => {
 })();
 
 function bytesFromBase64(b64: string): Uint8Array {
-  if (globalThis.Buffer) {
-    return Uint8Array.from(globalThis.Buffer.from(b64, "base64"));
+  if (tsProtoGlobalThis.Buffer) {
+    return Uint8Array.from(tsProtoGlobalThis.Buffer.from(b64, "base64"));
   } else {
-    const bin = globalThis.atob(b64);
+    const bin = tsProtoGlobalThis.atob(b64);
     const arr = new Uint8Array(bin.length);
     for (let i = 0; i < bin.length; ++i) {
       arr[i] = bin.charCodeAt(i);
@@ -551,14 +551,14 @@ function bytesFromBase64(b64: string): Uint8Array {
 }
 
 function base64FromBytes(arr: Uint8Array): string {
-  if (globalThis.Buffer) {
-    return globalThis.Buffer.from(arr).toString("base64");
+  if (tsProtoGlobalThis.Buffer) {
+    return tsProtoGlobalThis.Buffer.from(arr).toString("base64");
   } else {
     const bin: string[] = [];
     arr.forEach((byte) => {
       bin.push(String.fromCharCode(byte));
     });
-    return globalThis.btoa(bin.join(""));
+    return tsProtoGlobalThis.btoa(bin.join(""));
   }
 }
 
@@ -575,7 +575,7 @@ export type Exact<P, I extends P> = P extends Builtin ? P
 
 function longToNumber(long: Long): number {
   if (long.gt(Number.MAX_SAFE_INTEGER)) {
-    throw new globalThis.Error("Value is larger than Number.MAX_SAFE_INTEGER");
+    throw new tsProtoGlobalThis.Error("Value is larger than Number.MAX_SAFE_INTEGER");
   }
   return long.toNumber();
 }
diff --git a/integration/simple/simple.ts b/integration/simple/simple.ts
index b0881b28b..debfe590e 100644
--- a/integration/simple/simple.ts
+++ b/integration/simple/simple.ts
@@ -2346,7 +2346,7 @@ interface Rpc {
 declare var self: any | undefined;
 declare var window: any | undefined;
 declare var global: any | undefined;
-var globalThis: any = (() => {
+var tsProtoGlobalThis: any = (() => {
   if (typeof globalThis !== "undefined") {
     return globalThis;
   }
@@ -2363,10 +2363,10 @@ var globalThis: any = (() => {
 })();
 
 function bytesFromBase64(b64: string): Uint8Array {
-  if (globalThis.Buffer) {
-    return Uint8Array.from(globalThis.Buffer.from(b64, "base64"));
+  if (tsProtoGlobalThis.Buffer) {
+    return Uint8Array.from(tsProtoGlobalThis.Buffer.from(b64, "base64"));
   } else {
-    const bin = globalThis.atob(b64);
+    const bin = tsProtoGlobalThis.atob(b64);
     const arr = new Uint8Array(bin.length);
     for (let i = 0; i < bin.length; ++i) {
       arr[i] = bin.charCodeAt(i);
@@ -2376,14 +2376,14 @@ function bytesFromBase64(b64: string): Uint8Array {
 }
 
 function base64FromBytes(arr: Uint8Array): string {
-  if (globalThis.Buffer) {
-    return globalThis.Buffer.from(arr).toString("base64");
+  if (tsProtoGlobalThis.Buffer) {
+    return tsProtoGlobalThis.Buffer.from(arr).toString("base64");
   } else {
     const bin: string[] = [];
     arr.forEach((byte) => {
       bin.push(String.fromCharCode(byte));
     });
-    return globalThis.btoa(bin.join(""));
+    return tsProtoGlobalThis.btoa(bin.join(""));
   }
 }
 
@@ -2422,7 +2422,7 @@ function fromJsonTimestamp(o: any): Date {
 
 function longToNumber(long: Long): number {
   if (long.gt(Number.MAX_SAFE_INTEGER)) {
-    throw new globalThis.Error("Value is larger than Number.MAX_SAFE_INTEGER");
+    throw new tsProtoGlobalThis.Error("Value is larger than Number.MAX_SAFE_INTEGER");
   }
   return long.toNumber();
 }
diff --git a/integration/type-registry/google/protobuf/timestamp.ts b/integration/type-registry/google/protobuf/timestamp.ts
index bec2e71ed..c3ccbe66a 100644
--- a/integration/type-registry/google/protobuf/timestamp.ts
+++ b/integration/type-registry/google/protobuf/timestamp.ts
@@ -179,7 +179,7 @@ messageTypeRegistry.set(Timestamp.$type, Timestamp);
 declare var self: any | undefined;
 declare var window: any | undefined;
 declare var global: any | undefined;
-var globalThis: any = (() => {
+var tsProtoGlobalThis: any = (() => {
   if (typeof globalThis !== "undefined") {
     return globalThis;
   }
@@ -208,7 +208,7 @@ export type Exact<P, I extends P> = P extends Builtin ? P
 
 function longToNumber(long: Long): number {
   if (long.gt(Number.MAX_SAFE_INTEGER)) {
-    throw new globalThis.Error("Value is larger than Number.MAX_SAFE_INTEGER");
+    throw new tsProtoGlobalThis.Error("Value is larger than Number.MAX_SAFE_INTEGER");
   }
   return long.toNumber();
 }
diff --git a/integration/unknown-fields/google/protobuf/compiler/plugin.ts b/integration/unknown-fields/google/protobuf/compiler/plugin.ts
index 81b022549..21528d58c 100644
--- a/integration/unknown-fields/google/protobuf/compiler/plugin.ts
+++ b/integration/unknown-fields/google/protobuf/compiler/plugin.ts
@@ -415,7 +415,7 @@ export const CodeGeneratorResponse_File = {
 declare var self: any | undefined;
 declare var window: any | undefined;
 declare var global: any | undefined;
-var globalThis: any = (() => {
+var tsProtoGlobalThis: any = (() => {
   if (typeof globalThis !== "undefined") {
     return globalThis;
   }
@@ -433,7 +433,7 @@ var globalThis: any = (() => {
 
 function longToNumber(long: Long): number {
   if (long.gt(Number.MAX_SAFE_INTEGER)) {
-    throw new globalThis.Error("Value is larger than Number.MAX_SAFE_INTEGER");
+    throw new tsProtoGlobalThis.Error("Value is larger than Number.MAX_SAFE_INTEGER");
   }
   return long.toNumber();
 }
diff --git a/integration/unknown-fields/google/protobuf/descriptor.ts b/integration/unknown-fields/google/protobuf/descriptor.ts
index 86529d1af..fcf9f0783 100644
--- a/integration/unknown-fields/google/protobuf/descriptor.ts
+++ b/integration/unknown-fields/google/protobuf/descriptor.ts
@@ -2952,7 +2952,7 @@ export const GeneratedCodeInfo_Annotation = {
 declare var self: any | undefined;
 declare var window: any | undefined;
 declare var global: any | undefined;
-var globalThis: any = (() => {
+var tsProtoGlobalThis: any = (() => {
   if (typeof globalThis !== "undefined") {
     return globalThis;
   }
@@ -2970,7 +2970,7 @@ var globalThis: any = (() => {
 
 function longToNumber(long: Long): number {
   if (long.gt(Number.MAX_SAFE_INTEGER)) {
-    throw new globalThis.Error("Value is larger than Number.MAX_SAFE_INTEGER");
+    throw new tsProtoGlobalThis.Error("Value is larger than Number.MAX_SAFE_INTEGER");
   }
   return long.toNumber();
 }
diff --git a/integration/use-date-false/google/protobuf/timestamp.ts b/integration/use-date-false/google/protobuf/timestamp.ts
index 5497f7183..1825e1607 100644
--- a/integration/use-date-false/google/protobuf/timestamp.ts
+++ b/integration/use-date-false/google/protobuf/timestamp.ts
@@ -172,7 +172,7 @@ export const Timestamp = {
 declare var self: any | undefined;
 declare var window: any | undefined;
 declare var global: any | undefined;
-var globalThis: any = (() => {
+var tsProtoGlobalThis: any = (() => {
   if (typeof globalThis !== "undefined") {
     return globalThis;
   }
@@ -201,7 +201,7 @@ export type Exact<P, I extends P> = P extends Builtin ? P
 
 function longToNumber(long: Long): number {
   if (long.gt(Number.MAX_SAFE_INTEGER)) {
-    throw new globalThis.Error("Value is larger than Number.MAX_SAFE_INTEGER");
+    throw new tsProtoGlobalThis.Error("Value is larger than Number.MAX_SAFE_INTEGER");
   }
   return long.toNumber();
 }
diff --git a/integration/use-date-string/google/protobuf/timestamp.ts b/integration/use-date-string/google/protobuf/timestamp.ts
index 5497f7183..1825e1607 100644
--- a/integration/use-date-string/google/protobuf/timestamp.ts
+++ b/integration/use-date-string/google/protobuf/timestamp.ts
@@ -172,7 +172,7 @@ export const Timestamp = {
 declare var self: any | undefined;
 declare var window: any | undefined;
 declare var global: any | undefined;
-var globalThis: any = (() => {
+var tsProtoGlobalThis: any = (() => {
   if (typeof globalThis !== "undefined") {
     return globalThis;
   }
@@ -201,7 +201,7 @@ export type Exact<P, I extends P> = P extends Builtin ? P
 
 function longToNumber(long: Long): number {
   if (long.gt(Number.MAX_SAFE_INTEGER)) {
-    throw new globalThis.Error("Value is larger than Number.MAX_SAFE_INTEGER");
+    throw new tsProtoGlobalThis.Error("Value is larger than Number.MAX_SAFE_INTEGER");
   }
   return long.toNumber();
 }
diff --git a/integration/use-date-true/google/protobuf/timestamp.ts b/integration/use-date-true/google/protobuf/timestamp.ts
index 5497f7183..1825e1607 100644
--- a/integration/use-date-true/google/protobuf/timestamp.ts
+++ b/integration/use-date-true/google/protobuf/timestamp.ts
@@ -172,7 +172,7 @@ export const Timestamp = {
 declare var self: any | undefined;
 declare var window: any | undefined;
 declare var global: any | undefined;
-var globalThis: any = (() => {
+var tsProtoGlobalThis: any = (() => {
   if (typeof globalThis !== "undefined") {
     return globalThis;
   }
@@ -201,7 +201,7 @@ export type Exact<P, I extends P> = P extends Builtin ? P
 
 function longToNumber(long: Long): number {
   if (long.gt(Number.MAX_SAFE_INTEGER)) {
-    throw new globalThis.Error("Value is larger than Number.MAX_SAFE_INTEGER");
+    throw new tsProtoGlobalThis.Error("Value is larger than Number.MAX_SAFE_INTEGER");
   }
   return long.toNumber();
 }
diff --git a/integration/use-map-type/google/protobuf/timestamp.ts b/integration/use-map-type/google/protobuf/timestamp.ts
index 5497f7183..1825e1607 100644
--- a/integration/use-map-type/google/protobuf/timestamp.ts
+++ b/integration/use-map-type/google/protobuf/timestamp.ts
@@ -172,7 +172,7 @@ export const Timestamp = {
 declare var self: any | undefined;
 declare var window: any | undefined;
 declare var global: any | undefined;
-var globalThis: any = (() => {
+var tsProtoGlobalThis: any = (() => {
   if (typeof globalThis !== "undefined") {
     return globalThis;
   }
@@ -201,7 +201,7 @@ export type Exact<P, I extends P> = P extends Builtin ? P
 
 function longToNumber(long: Long): number {
   if (long.gt(Number.MAX_SAFE_INTEGER)) {
-    throw new globalThis.Error("Value is larger than Number.MAX_SAFE_INTEGER");
+    throw new tsProtoGlobalThis.Error("Value is larger than Number.MAX_SAFE_INTEGER");
   }
   return long.toNumber();
 }
diff --git a/integration/use-map-type/use-map-type.ts b/integration/use-map-type/use-map-type.ts
index c05fd502f..158713474 100644
--- a/integration/use-map-type/use-map-type.ts
+++ b/integration/use-map-type/use-map-type.ts
@@ -575,7 +575,7 @@ export const Maps_MapOfTimestampsEntry = {
 declare var self: any | undefined;
 declare var window: any | undefined;
 declare var global: any | undefined;
-var globalThis: any = (() => {
+var tsProtoGlobalThis: any = (() => {
   if (typeof globalThis !== "undefined") {
     return globalThis;
   }
@@ -592,10 +592,10 @@ var globalThis: any = (() => {
 })();
 
 function bytesFromBase64(b64: string): Uint8Array {
-  if (globalThis.Buffer) {
-    return Uint8Array.from(globalThis.Buffer.from(b64, "base64"));
+  if (tsProtoGlobalThis.Buffer) {
+    return Uint8Array.from(tsProtoGlobalThis.Buffer.from(b64, "base64"));
   } else {
-    const bin = globalThis.atob(b64);
+    const bin = tsProtoGlobalThis.atob(b64);
     const arr = new Uint8Array(bin.length);
     for (let i = 0; i < bin.length; ++i) {
       arr[i] = bin.charCodeAt(i);
@@ -605,14 +605,14 @@ function bytesFromBase64(b64: string): Uint8Array {
 }
 
 function base64FromBytes(arr: Uint8Array): string {
-  if (globalThis.Buffer) {
-    return globalThis.Buffer.from(arr).toString("base64");
+  if (tsProtoGlobalThis.Buffer) {
+    return tsProtoGlobalThis.Buffer.from(arr).toString("base64");
   } else {
     const bin: string[] = [];
     arr.forEach((byte) => {
       bin.push(String.fromCharCode(byte));
     });
-    return globalThis.btoa(bin.join(""));
+    return tsProtoGlobalThis.btoa(bin.join(""));
   }
 }
 
@@ -651,7 +651,7 @@ function fromJsonTimestamp(o: any): Date {
 
 function longToNumber(long: Long): number {
   if (long.gt(Number.MAX_SAFE_INTEGER)) {
-    throw new globalThis.Error("Value is larger than Number.MAX_SAFE_INTEGER");
+    throw new tsProtoGlobalThis.Error("Value is larger than Number.MAX_SAFE_INTEGER");
   }
   return long.toNumber();
 }
diff --git a/integration/use-optionals-all/test.ts b/integration/use-optionals-all/test.ts
index 3cf686dd6..6e18858f9 100644
--- a/integration/use-optionals-all/test.ts
+++ b/integration/use-optionals-all/test.ts
@@ -540,7 +540,7 @@ export const Child = {
 declare var self: any | undefined;
 declare var window: any | undefined;
 declare var global: any | undefined;
-var globalThis: any = (() => {
+var tsProtoGlobalThis: any = (() => {
   if (typeof globalThis !== "undefined") {
     return globalThis;
   }
@@ -557,10 +557,10 @@ var globalThis: any = (() => {
 })();
 
 function bytesFromBase64(b64: string): Uint8Array {
-  if (globalThis.Buffer) {
-    return Uint8Array.from(globalThis.Buffer.from(b64, "base64"));
+  if (tsProtoGlobalThis.Buffer) {
+    return Uint8Array.from(tsProtoGlobalThis.Buffer.from(b64, "base64"));
   } else {
-    const bin = globalThis.atob(b64);
+    const bin = tsProtoGlobalThis.atob(b64);
     const arr = new Uint8Array(bin.length);
     for (let i = 0; i < bin.length; ++i) {
       arr[i] = bin.charCodeAt(i);
@@ -570,14 +570,14 @@ function bytesFromBase64(b64: string): Uint8Array {
 }
 
 function base64FromBytes(arr: Uint8Array): string {
-  if (globalThis.Buffer) {
-    return globalThis.Buffer.from(arr).toString("base64");
+  if (tsProtoGlobalThis.Buffer) {
+    return tsProtoGlobalThis.Buffer.from(arr).toString("base64");
   } else {
     const bin: string[] = [];
     arr.forEach((byte) => {
       bin.push(String.fromCharCode(byte));
     });
-    return globalThis.btoa(bin.join(""));
+    return tsProtoGlobalThis.btoa(bin.join(""));
   }
 }
 
@@ -594,7 +594,7 @@ export type Exact<P, I extends P> = P extends Builtin ? P
 
 function longToNumber(long: Long): number {
   if (long.gt(Number.MAX_SAFE_INTEGER)) {
-    throw new globalThis.Error("Value is larger than Number.MAX_SAFE_INTEGER");
+    throw new tsProtoGlobalThis.Error("Value is larger than Number.MAX_SAFE_INTEGER");
   }
   return long.toNumber();
 }
diff --git a/integration/value/google/protobuf/wrappers.ts b/integration/value/google/protobuf/wrappers.ts
index 3145298cb..901cd737e 100644
--- a/integration/value/google/protobuf/wrappers.ts
+++ b/integration/value/google/protobuf/wrappers.ts
@@ -521,7 +521,7 @@ export const BytesValue = {
 declare var self: any | undefined;
 declare var window: any | undefined;
 declare var global: any | undefined;
-var globalThis: any = (() => {
+var tsProtoGlobalThis: any = (() => {
   if (typeof globalThis !== "undefined") {
     return globalThis;
   }
@@ -538,10 +538,10 @@ var globalThis: any = (() => {
 })();
 
 function bytesFromBase64(b64: string): Uint8Array {
-  if (globalThis.Buffer) {
-    return Uint8Array.from(globalThis.Buffer.from(b64, "base64"));
+  if (tsProtoGlobalThis.Buffer) {
+    return Uint8Array.from(tsProtoGlobalThis.Buffer.from(b64, "base64"));
   } else {
-    const bin = globalThis.atob(b64);
+    const bin = tsProtoGlobalThis.atob(b64);
     const arr = new Uint8Array(bin.length);
     for (let i = 0; i < bin.length; ++i) {
       arr[i] = bin.charCodeAt(i);
@@ -551,14 +551,14 @@ function bytesFromBase64(b64: string): Uint8Array {
 }
 
 function base64FromBytes(arr: Uint8Array): string {
-  if (globalThis.Buffer) {
-    return globalThis.Buffer.from(arr).toString("base64");
+  if (tsProtoGlobalThis.Buffer) {
+    return tsProtoGlobalThis.Buffer.from(arr).toString("base64");
   } else {
     const bin: string[] = [];
     arr.forEach((byte) => {
       bin.push(String.fromCharCode(byte));
     });
-    return globalThis.btoa(bin.join(""));
+    return tsProtoGlobalThis.btoa(bin.join(""));
   }
 }
 
@@ -575,7 +575,7 @@ export type Exact<P, I extends P> = P extends Builtin ? P
 
 function longToNumber(long: Long): number {
   if (long.gt(Number.MAX_SAFE_INTEGER)) {
-    throw new globalThis.Error("Value is larger than Number.MAX_SAFE_INTEGER");
+    throw new tsProtoGlobalThis.Error("Value is larger than Number.MAX_SAFE_INTEGER");
   }
   return long.toNumber();
 }
diff --git a/integration/vector-tile/vector_tile.ts b/integration/vector-tile/vector_tile.ts
index d8b628bb4..a8a77a25d 100644
--- a/integration/vector-tile/vector_tile.ts
+++ b/integration/vector-tile/vector_tile.ts
@@ -444,7 +444,7 @@ export const Tile_Layer = {
 declare var self: any | undefined;
 declare var window: any | undefined;
 declare var global: any | undefined;
-var globalThis: any = (() => {
+var tsProtoGlobalThis: any = (() => {
   if (typeof globalThis !== "undefined") {
     return globalThis;
   }
@@ -473,7 +473,7 @@ export type Exact<P, I extends P> = P extends Builtin ? P
 
 function longToNumber(long: Long): number {
   if (long.gt(Number.MAX_SAFE_INTEGER)) {
-    throw new globalThis.Error("Value is larger than Number.MAX_SAFE_INTEGER");
+    throw new tsProtoGlobalThis.Error("Value is larger than Number.MAX_SAFE_INTEGER");
   }
   return long.toNumber();
 }
diff --git a/integration/wrappers-regression/google/protobuf/timestamp.ts b/integration/wrappers-regression/google/protobuf/timestamp.ts
index 5497f7183..1825e1607 100644
--- a/integration/wrappers-regression/google/protobuf/timestamp.ts
+++ b/integration/wrappers-regression/google/protobuf/timestamp.ts
@@ -172,7 +172,7 @@ export const Timestamp = {
 declare var self: any | undefined;
 declare var window: any | undefined;
 declare var global: any | undefined;
-var globalThis: any = (() => {
+var tsProtoGlobalThis: any = (() => {
   if (typeof globalThis !== "undefined") {
     return globalThis;
   }
@@ -201,7 +201,7 @@ export type Exact<P, I extends P> = P extends Builtin ? P
 
 function longToNumber(long: Long): number {
   if (long.gt(Number.MAX_SAFE_INTEGER)) {
-    throw new globalThis.Error("Value is larger than Number.MAX_SAFE_INTEGER");
+    throw new tsProtoGlobalThis.Error("Value is larger than Number.MAX_SAFE_INTEGER");
   }
   return long.toNumber();
 }
diff --git a/integration/wrappers-regression/google/protobuf/wrappers.ts b/integration/wrappers-regression/google/protobuf/wrappers.ts
index 3145298cb..901cd737e 100644
--- a/integration/wrappers-regression/google/protobuf/wrappers.ts
+++ b/integration/wrappers-regression/google/protobuf/wrappers.ts
@@ -521,7 +521,7 @@ export const BytesValue = {
 declare var self: any | undefined;
 declare var window: any | undefined;
 declare var global: any | undefined;
-var globalThis: any = (() => {
+var tsProtoGlobalThis: any = (() => {
   if (typeof globalThis !== "undefined") {
     return globalThis;
   }
@@ -538,10 +538,10 @@ var globalThis: any = (() => {
 })();
 
 function bytesFromBase64(b64: string): Uint8Array {
-  if (globalThis.Buffer) {
-    return Uint8Array.from(globalThis.Buffer.from(b64, "base64"));
+  if (tsProtoGlobalThis.Buffer) {
+    return Uint8Array.from(tsProtoGlobalThis.Buffer.from(b64, "base64"));
   } else {
-    const bin = globalThis.atob(b64);
+    const bin = tsProtoGlobalThis.atob(b64);
     const arr = new Uint8Array(bin.length);
     for (let i = 0; i < bin.length; ++i) {
       arr[i] = bin.charCodeAt(i);
@@ -551,14 +551,14 @@ function bytesFromBase64(b64: string): Uint8Array {
 }
 
 function base64FromBytes(arr: Uint8Array): string {
-  if (globalThis.Buffer) {
-    return globalThis.Buffer.from(arr).toString("base64");
+  if (tsProtoGlobalThis.Buffer) {
+    return tsProtoGlobalThis.Buffer.from(arr).toString("base64");
   } else {
     const bin: string[] = [];
     arr.forEach((byte) => {
       bin.push(String.fromCharCode(byte));
     });
-    return globalThis.btoa(bin.join(""));
+    return tsProtoGlobalThis.btoa(bin.join(""));
   }
 }
 
@@ -575,7 +575,7 @@ export type Exact<P, I extends P> = P extends Builtin ? P
 
 function longToNumber(long: Long): number {
   if (long.gt(Number.MAX_SAFE_INTEGER)) {
-    throw new globalThis.Error("Value is larger than Number.MAX_SAFE_INTEGER");
+    throw new tsProtoGlobalThis.Error("Value is larger than Number.MAX_SAFE_INTEGER");
   }
   return long.toNumber();
 }
diff --git a/src/main.ts b/src/main.ts
index 548c33e27..7828fee65 100644
--- a/src/main.ts
+++ b/src/main.ts
@@ -340,7 +340,7 @@ export function makeUtils(options: Options): Utils {
     ...longs,
     ...makeComparisonUtils(),
     ...makeNiceGrpcServerStreamingMethodResult(),
-    ...makeGrpcWebErrorClass(),
+    ...makeGrpcWebErrorClass(bytes),
   };
 }
 
@@ -434,12 +434,12 @@ function makeLongUtils(options: Options, bytes: ReturnType<typeof makeByteUtils>
 
 function makeByteUtils() {
   const globalThis = conditionalOutput(
-    "globalThis",
+    "tsProtoGlobalThis",
     code`
       declare var self: any | undefined;
       declare var window: any | undefined;
       declare var global: any | undefined;
-      var globalThis: any = (() => {
+      var tsProtoGlobalThis: any = (() => {
         if (typeof globalThis !== "undefined") return globalThis;
         if (typeof self !== "undefined") return self;
         if (typeof window !== "undefined") return window;
@@ -698,11 +698,11 @@ function makeNiceGrpcServerStreamingMethodResult() {
   return { NiceGrpcServerStreamingMethodResult };
 }
 
-function makeGrpcWebErrorClass() {
+function makeGrpcWebErrorClass(bytes: ReturnType<typeof makeByteUtils>) {
   const GrpcWebError = conditionalOutput(
     "GrpcWebError",
     code`
-      export class GrpcWebError extends globalThis.Error {
+      export class GrpcWebError extends ${bytes.globalThis}.Error {
         constructor(message: string, public code: grpc.Code, public metadata: grpc.Metadata) {
           super(message);
         }