diff --git a/CHANGES b/CHANGES
index a1b2479a3c..44faffea9e 100644
--- a/CHANGES
+++ b/CHANGES
@@ -24,6 +24,8 @@ Bugs fixed
 ----------
 
 * #10133: autodoc: Crashed when mocked module is used for type annotation
+* #10146: autodoc: :confval:`autodoc_default_options` does not support
+  ``no-value`` option
 * #10122: sphinx-build: make.bat does not check the installation of sphinx-build
   command before showing help
 
diff --git a/doc/usage/extensions/autodoc.rst b/doc/usage/extensions/autodoc.rst
index dfb08e688e..3849f4713a 100644
--- a/doc/usage/extensions/autodoc.rst
+++ b/doc/usage/extensions/autodoc.rst
@@ -528,7 +528,8 @@ There are also config values that you can set:
    The supported options are ``'members'``, ``'member-order'``,
    ``'undoc-members'``, ``'private-members'``, ``'special-members'``,
    ``'inherited-members'``, ``'show-inheritance'``, ``'ignore-module-all'``,
-   ``'imported-members'``, ``'exclude-members'`` and ``'class-doc-from'``.
+   ``'imported-members'``, ``'exclude-members'``, ``'class-doc-from'`` and
+   ``'no-value'``.
 
    .. versionadded:: 1.8
 
@@ -541,6 +542,9 @@ There are also config values that you can set:
    .. versionchanged:: 4.1
       Added ``'class-doc-from'``.
 
+   .. versionchanged:: 4.5
+      Added ``'class-doc-from'``.
+
 .. confval:: autodoc_docstring_signature
 
    Functions imported from C modules cannot be introspected, and therefore the
diff --git a/sphinx/ext/autodoc/__init__.py b/sphinx/ext/autodoc/__init__.py
index 8a86f05b1a..0e88d914c4 100644
--- a/sphinx/ext/autodoc/__init__.py
+++ b/sphinx/ext/autodoc/__init__.py
@@ -1001,7 +1001,8 @@ class ModuleDocumenter(Documenter):
         'platform': identity, 'deprecated': bool_option,
         'member-order': member_order_option, 'exclude-members': exclude_members_option,
         'private-members': members_option, 'special-members': members_option,
-        'imported-members': bool_option, 'ignore-module-all': bool_option
+        'imported-members': bool_option, 'ignore-module-all': bool_option,
+        'no-value': bool_option,
     }
 
     def __init__(self, *args: Any) -> None:
diff --git a/sphinx/ext/autodoc/directive.py b/sphinx/ext/autodoc/directive.py
index 8b8048f8a9..0c040e1ef3 100644
--- a/sphinx/ext/autodoc/directive.py
+++ b/sphinx/ext/autodoc/directive.py
@@ -30,7 +30,7 @@
 AUTODOC_DEFAULT_OPTIONS = ['members', 'undoc-members', 'inherited-members',
                            'show-inheritance', 'private-members', 'special-members',
                            'ignore-module-all', 'exclude-members', 'member-order',
-                           'imported-members', 'class-doc-from']
+                           'imported-members', 'class-doc-from', 'no-value']
 
 AUTODOC_EXTENDABLE_OPTIONS = ['members', 'private-members', 'special-members',
                               'exclude-members']