diff --git a/packages/core/src/config.ts b/packages/core/src/config.ts
index 93311ed03c..4d8211af72 100644
--- a/packages/core/src/config.ts
+++ b/packages/core/src/config.ts
@@ -1,4 +1,4 @@
-import type { Postprocessor, Preprocessor, ResolvedConfig, Shortcut, ThemeExtender, UserConfig, UserConfigDefaults, UserShortcuts } from './types'
+import type { Postprocessor, Preprocessor, Preset, ResolvedConfig, Shortcut, ThemeExtender, UserConfig, UserConfigDefaults, UserShortcuts } from './types'
 import { clone, isStaticRule, mergeDeep, normalizeVariant, toArray, uniq } from './utils'
 import { extractorSplit } from './extractors'
 import { DEAFULT_LAYERS } from './constants'
@@ -11,12 +11,24 @@ export function resolveShortcuts(shortcuts: UserShortcuts): Shortcut[] {
   })
 }
 
+export function resolvePreset(preset: Preset): Preset {
+  if (preset.prefix) {
+    preset.rules?.forEach((i) => {
+      if (i[2])
+        i[2].prefix ||= preset.prefix
+      else
+        i[2] = { prefix: preset.prefix }
+    })
+  }
+  return preset
+}
+
 export function resolveConfig(
   userConfig: UserConfig = {},
   defaults: UserConfigDefaults = {},
 ): ResolvedConfig {
   const config = Object.assign({}, defaults, userConfig) as UserConfigDefaults
-  const rawPresets = (config.presets || []).flatMap(toArray)
+  const rawPresets = (config.presets || []).flatMap(toArray).map(resolvePreset)
 
   const sortedPresets = [
     ...rawPresets.filter(p => p.enforce === 'pre'),
@@ -45,7 +57,8 @@ export function resolveConfig(
 
   rules.forEach((rule, i) => {
     if (isStaticRule(rule)) {
-      rulesStaticMap[rule[0]] = [i, rule[1], rule[2], rule]
+      const prefix = rule[2]?.prefix || ''
+      rulesStaticMap[prefix + rule[0]] = [i, rule[1], rule[2], rule]
       // delete static rules so we can't skip them in matching
       // but keep the order
       delete rules[i]
diff --git a/packages/core/src/generator/index.ts b/packages/core/src/generator/index.ts
index 1a037e9ef3..4ffe7218f6 100644
--- a/packages/core/src/generator/index.ts
+++ b/packages/core/src/generator/index.ts
@@ -445,7 +445,10 @@ export class UnoGenerator {
 
       // dynamic rules
       const [matcher, handler, meta] = rule
-      const match = processed.match(matcher)
+      if (meta?.prefix && !processed.startsWith(meta.prefix))
+        continue
+      const unprefixed = meta?.prefix ? processed.slice(meta.prefix.length) : processed
+      const match = unprefixed.match(matcher)
       if (!match)
         continue
 
diff --git a/packages/core/src/types.ts b/packages/core/src/types.ts
index f42b4841c2..d49078cbbd 100644
--- a/packages/core/src/types.ts
+++ b/packages/core/src/types.ts
@@ -157,6 +157,11 @@ export interface RuleMeta {
    */
   autocomplete?: Arrayable<AutoCompleteTemplate>
 
+  /**
+   * Matching prefix before this util
+   */
+  prefix?: string
+
   /**
    * Internal rules will only be matched for shortcuts but not the user code.
    * @default false
@@ -449,6 +454,10 @@ export interface Preset<Theme extends {} = {}> extends ConfigBase<Theme> {
    * Preset options for other tools like IDE to consume
    */
   options?: PresetOptions
+  /**
+   * Apply prefix to all utilities
+   */
+  prefix?: string
 }
 
 export interface GeneratorOptions {
diff --git a/packages/preset-mini/src/index.ts b/packages/preset-mini/src/index.ts
index 985c5f7c87..67514b4b21 100644
--- a/packages/preset-mini/src/index.ts
+++ b/packages/preset-mini/src/index.ts
@@ -24,6 +24,12 @@ export interface PresetMiniOptions extends PresetOptions {
    * @default 'un-'
    */
   variablePrefix?: string
+  /**
+   * Utils prefix
+   *
+   * @default undefined
+   */
+  prefix?: string
 }
 
 export const presetMini = (options: PresetMiniOptions = {}): Preset<Theme> => {
@@ -40,6 +46,7 @@ export const presetMini = (options: PresetMiniOptions = {}): Preset<Theme> => {
       ? VarPrefixPostprocessor(options.variablePrefix)
       : undefined,
     preflights,
+    prefix: options.prefix,
   }
 }
 
diff --git a/packages/preset-uno/src/index.ts b/packages/preset-uno/src/index.ts
index fc43892a92..6b58b7cee1 100644
--- a/packages/preset-uno/src/index.ts
+++ b/packages/preset-uno/src/index.ts
@@ -23,6 +23,7 @@ export const presetUno = (options: PresetUnoOptions = {}): Preset<Theme> => {
     ],
     options,
     preflights,
+    prefix: options.prefix,
   }
 }
 
diff --git a/packages/preset-wind/src/index.ts b/packages/preset-wind/src/index.ts
index b0923b57cd..6682ea0028 100644
--- a/packages/preset-wind/src/index.ts
+++ b/packages/preset-wind/src/index.ts
@@ -26,6 +26,7 @@ export const presetWind = (options: PresetWindOptions = {}): Preset<Theme> => {
     variants: variants(options),
     options,
     preflights,
+    prefix: options.prefix,
   }
 }
 
diff --git a/test/__snapshots__/prefix.test.ts.snap b/test/__snapshots__/prefix.test.ts.snap
index 12fb7a9075..3e5d89beee 100644
--- a/test/__snapshots__/prefix.test.ts.snap
+++ b/test/__snapshots__/prefix.test.ts.snap
@@ -1,29 +1,8 @@
 // Vitest Snapshot v1
 
-exports[`prefix 1`] = `
-"/* layer: icons */
-.dark .uno\\\\:dark\\\\:i-carbon-moon{--un-icon:url(\\"data:image/svg+xml;utf8,%3Csvg preserveAspectRatio='xMidYMid meet' viewBox='0 0 32 32' width='1em' height='1em' xmlns='http://www.w3.org/2000/svg' %3E%3Cpath fill='currentColor' d='M13.502 5.414a15.075 15.075 0 0 0 11.594 18.194a11.113 11.113 0 0 1-7.975 3.39c-.138 0-.278.005-.418 0a11.094 11.094 0 0 1-3.2-21.584M14.98 3a1.002 1.002 0 0 0-.175.016a13.096 13.096 0 0 0 1.825 25.981c.164.006.328 0 .49 0a13.072 13.072 0 0 0 10.703-5.555a1.01 1.01 0 0 0-.783-1.565A13.08 13.08 0 0 1 15.89 4.38A1.015 1.015 0 0 0 14.98 3Z'/%3E%3C/svg%3E\\");mask:var(--un-icon) no-repeat;mask-size:100% 100%;-webkit-mask:var(--un-icon) no-repeat;-webkit-mask-size:100% 100%;background-color:currentColor;width:1em;height:1em;}
-/* layer: shortcuts */
-.uno\\\\:btn{margin-right:2.5rem;}
-.uno\\\\:btn1{margin-left:2.5rem;margin-right:2.5rem;}
-/* layer: default */
-.uno\\\\:\\\\!p-5px{padding:5px !important;}
-.uno\\\\:hover\\\\:p-4:hover{padding:1rem;}
-.uno\\\\:pl-10px{padding-left:10px;}
-@media (min-width: 640px){
-.uno\\\\:sm\\\\:p-6{padding:1.5rem;}
-}"
-`;
-
-exports[`tailwind prefix 1`] = `
-"/* layer: shortcuts */
-.uno-btn{margin-right:2.5rem;}
-.uno\\\\:btn1{margin-left:2.5rem;margin-right:2.5rem;}
-/* layer: default */
-.\\\\!uno\\\\:p-5px{padding:5px !important;}
-.hover\\\\:uno\\\\:p-4:hover{padding:1rem;}
-.uno\\\\:pl-10px{padding-left:10px;}
-@media (min-width: 640px){
-.sm\\\\:uno\\\\:p-6{padding:1.5rem;}
-}"
+exports[`prefix > preset prefix 2`] = `
+"/* layer: default */
+.hover\\\\:foo-p4:hover{padding:1rem;}
+.foo-text-red{--un-text-opacity:1;color:rgba(248,113,113,var(--un-text-opacity));}
+.bar-bar{color:bar;}"
 `;
diff --git a/test/__snapshots__/preprocess.test.ts.snap b/test/__snapshots__/preprocess.test.ts.snap
new file mode 100644
index 0000000000..f485ef49ce
--- /dev/null
+++ b/test/__snapshots__/preprocess.test.ts.snap
@@ -0,0 +1,29 @@
+// Vitest Snapshot v1
+
+exports[`preprocess > prefix 1`] = `
+"/* layer: icons */
+.dark .uno\\\\:dark\\\\:i-carbon-moon{--un-icon:url(\\"data:image/svg+xml;utf8,%3Csvg preserveAspectRatio='xMidYMid meet' viewBox='0 0 32 32' width='1em' height='1em' xmlns='http://www.w3.org/2000/svg' %3E%3Cpath fill='currentColor' d='M13.502 5.414a15.075 15.075 0 0 0 11.594 18.194a11.113 11.113 0 0 1-7.975 3.39c-.138 0-.278.005-.418 0a11.094 11.094 0 0 1-3.2-21.584M14.98 3a1.002 1.002 0 0 0-.175.016a13.096 13.096 0 0 0 1.825 25.981c.164.006.328 0 .49 0a13.072 13.072 0 0 0 10.703-5.555a1.01 1.01 0 0 0-.783-1.565A13.08 13.08 0 0 1 15.89 4.38A1.015 1.015 0 0 0 14.98 3Z'/%3E%3C/svg%3E\\");mask:var(--un-icon) no-repeat;mask-size:100% 100%;-webkit-mask:var(--un-icon) no-repeat;-webkit-mask-size:100% 100%;background-color:currentColor;width:1em;height:1em;}
+/* layer: shortcuts */
+.uno\\\\:btn{margin-right:2.5rem;}
+.uno\\\\:btn1{margin-left:2.5rem;margin-right:2.5rem;}
+/* layer: default */
+.uno\\\\:\\\\!p-5px{padding:5px !important;}
+.uno\\\\:hover\\\\:p-4:hover{padding:1rem;}
+.uno\\\\:pl-10px{padding-left:10px;}
+@media (min-width: 640px){
+.uno\\\\:sm\\\\:p-6{padding:1.5rem;}
+}"
+`;
+
+exports[`preprocess > tailwind prefix 1`] = `
+"/* layer: shortcuts */
+.uno-btn{margin-right:2.5rem;}
+.uno\\\\:btn1{margin-left:2.5rem;margin-right:2.5rem;}
+/* layer: default */
+.\\\\!uno\\\\:p-5px{padding:5px !important;}
+.hover\\\\:uno\\\\:p-4:hover{padding:1rem;}
+.uno\\\\:pl-10px{padding-left:10px;}
+@media (min-width: 640px){
+.sm\\\\:uno\\\\:p-6{padding:1.5rem;}
+}"
+`;
diff --git a/test/prefix.test.ts b/test/prefix.test.ts
index deb03e1aeb..b12313e810 100644
--- a/test/prefix.test.ts
+++ b/test/prefix.test.ts
@@ -1,75 +1,35 @@
 import { createGenerator } from '@unocss/core'
-import presetUno from '@unocss/preset-uno'
-import presetIcons from '@unocss/preset-icons'
-import { expect, test } from 'vitest'
+import { describe, expect, test } from 'vitest'
+import presetMini from '@unocss/preset-mini'
 
-test('prefix', async () => {
-  const positive = [
-    'uno:pl-10px',
-    'uno:hover:p-4',
-    'uno:sm:p-6',
-    'uno:!p-5px',
-    'uno:btn',
-    'uno:btn1',
-    'uno:dark:i-carbon-moon',
-  ]
+describe('prefix', () => {
+  test('preset prefix', async () => {
+    const uno = createGenerator({
+      presets: [
+        presetMini({ prefix: 'foo-' }),
+      ],
+      rules: [
+        ['bar', { color: 'bar' }, { prefix: 'bar-' }],
+      ],
+    })
 
-  const negative = [
-    'pl-10px',
-    'hover:p-4',
-    '!p-5px',
-    'btn',
-    'btn1',
-    'i-carbon-moon',
-  ]
+    const { css, matched } = await uno.generate(new Set([
+      'text-red',
+      'foo-text-red',
+      'hover:p4',
+      'hover:foo-p4',
+      'bar',
+      'bar-bar',
+    ]), { preflights: false })
 
-  const uno = createGenerator({
-    preprocess: m => m.startsWith('uno:') ? m.substr(4) : '',
-    presets: [
-      presetUno(),
-      presetIcons(),
-    ],
-    shortcuts: {
-      btn: 'mr-10',
-      btn1: 'ml-10 btn',
-    },
-  })
-  const { css, matched } = await uno.generate(new Set([...positive, ...negative]), { preflights: false })
-  expect(matched).eql(new Set(positive))
-  expect(css).toMatchSnapshot()
-})
-
-test('tailwind prefix', async () => {
-  const positive = [
-    'uno:pl-10px',
-    'hover:uno:p-4',
-    'sm:uno:p-6',
-    '!uno:p-5px',
-    'uno-btn',
-    'uno:btn1',
-  ]
-
-  const negative = [
-    'pl-10px',
-    'hover:p-4',
-    '!p-5px',
-    'btn',
-    'btn1',
-  ]
+    expect(matched).toMatchInlineSnapshot(`
+      Set {
+        "bar-bar",
+        "foo-text-red",
+        "hover:foo-p4",
+      }
+    `)
 
-  const prefixRE = /uno[:-]/
-  const uno = createGenerator({
-    preprocess: m => prefixRE.test(m) ? m.replace(prefixRE, '') : '',
-    presets: [
-      presetUno(),
-      presetIcons(),
-    ],
-    shortcuts: {
-      btn: 'mr-10',
-      btn1: 'ml-10 btn',
-    },
+    expect(css).toMatchSnapshot()
   })
-  const { css, matched } = await uno.generate(new Set([...positive, ...negative]), { preflights: false })
-  expect(matched).eql(new Set(positive))
-  expect(css).toMatchSnapshot()
 })
diff --git a/test/preprocess.test.ts b/test/preprocess.test.ts
new file mode 100644
index 0000000000..ec7695ad00
--- /dev/null
+++ b/test/preprocess.test.ts
@@ -0,0 +1,77 @@
+import { createGenerator } from '@unocss/core'
+import presetUno from '@unocss/preset-uno'
+import presetIcons from '@unocss/preset-icons'
+import { describe, expect, test } from 'vitest'
+
+describe('preprocess', () => {
+  test('prefix', async () => {
+    const positive = [
+      'uno:pl-10px',
+      'uno:hover:p-4',
+      'uno:sm:p-6',
+      'uno:!p-5px',
+      'uno:btn',
+      'uno:btn1',
+      'uno:dark:i-carbon-moon',
+    ]
+
+    const negative = [
+      'pl-10px',
+      'hover:p-4',
+      '!p-5px',
+      'btn',
+      'btn1',
+      'i-carbon-moon',
+    ]
+
+    const uno = createGenerator({
+      preprocess: m => m.startsWith('uno:') ? m.substr(4) : '',
+      presets: [
+        presetUno(),
+        presetIcons(),
+      ],
+      shortcuts: {
+        btn: 'mr-10',
+        btn1: 'ml-10 btn',
+      },
+    })
+    const { css, matched } = await uno.generate(new Set([...positive, ...negative]), { preflights: false })
+    expect(matched).eql(new Set(positive))
+    expect(css).toMatchSnapshot()
+  })
+
+  test('tailwind prefix', async () => {
+    const positive = [
+      'uno:pl-10px',
+      'hover:uno:p-4',
+      'sm:uno:p-6',
+      '!uno:p-5px',
+      'uno-btn',
+      'uno:btn1',
+    ]
+
+    const negative = [
+      'pl-10px',
+      'hover:p-4',
+      '!p-5px',
+      'btn',
+      'btn1',
+    ]
+
+    const prefixRE = /uno[:-]/
+    const uno = createGenerator({
+      preprocess: m => prefixRE.test(m) ? m.replace(prefixRE, '') : '',
+      presets: [
+        presetUno(),
+        presetIcons(),
+      ],
+      shortcuts: {
+        btn: 'mr-10',
+        btn1: 'ml-10 btn',
+      },
+    })
+    const { css, matched } = await uno.generate(new Set([...positive, ...negative]), { preflights: false })
+    expect(matched).eql(new Set(positive))
+    expect(css).toMatchSnapshot()
+  })
+})