diff --git a/packages/next/build/webpack/plugins/nextjs-require-cache-hot-reloader.ts b/packages/next/build/webpack/plugins/nextjs-require-cache-hot-reloader.ts
index d661c1f3f379e5d..1cd9b47d1df0ff7 100644
--- a/packages/next/build/webpack/plugins/nextjs-require-cache-hot-reloader.ts
+++ b/packages/next/build/webpack/plugins/nextjs-require-cache-hot-reloader.ts
@@ -10,6 +10,8 @@ type WebpackPluginInstance = webpack.WebpackPluginInstance
 const originModules = [
   require.resolve('../../../server/require'),
   require.resolve('../../../server/load-components'),
+  require.resolve('../../../server/next-server'),
+  require.resolve('../../../compiled/react-server-dom-webpack/client'),
 ]
 
 const RUNTIME_NAMES = ['webpack-runtime', 'webpack-api-runtime']
diff --git a/packages/next/server/dev/next-dev-server.ts b/packages/next/server/dev/next-dev-server.ts
index c4dae0ce636173f..3b793ba777e35bc 100644
--- a/packages/next/server/dev/next-dev-server.ts
+++ b/packages/next/server/dev/next-dev-server.ts
@@ -109,6 +109,7 @@ export default class DevServer extends Server {
   private edgeFunctions?: RoutingItem[]
   private verifyingTypeScript?: boolean
   private usingTypeScript?: boolean
+  private originalFetch?: typeof fetch
 
   protected staticPathsWorker?: { [key: string]: any } & {
     loadStaticPaths: typeof import('./static-paths-worker').loadStaticPaths
@@ -149,6 +150,7 @@ export default class DevServer extends Server {
 
   constructor(options: Options) {
     super({ ...options, dev: true })
+    this.persistPatchedGlobals()
     this.renderOpts.dev = true
     ;(this.renderOpts as any).ErrorDebug = ReactDevOverlay
     this.devReady = new Promise((resolve) => {
@@ -1385,6 +1387,14 @@ export default class DevServer extends Server {
     return this.hotReloader!.ensurePage({ page: pathname, clientOnly: false })
   }
 
+  private persistPatchedGlobals(): void {
+    this.originalFetch = global.fetch
+  }
+
+  private restorePatchedGlobals(): void {
+    global.fetch = this.originalFetch!
+  }
+
   protected async findPageComponents({
     pathname,
     query,
@@ -1418,6 +1428,11 @@ export default class DevServer extends Server {
         this.serverCSSManifest = super.getServerCSSManifest()
       }
       this.fontLoaderManifest = super.getFontLoaderManifest()
+      // before we re-evaluate a route module, we want to restore globals that might
+      // have been patched previously to their original state so that we don't
+      // patch on top of the previous patch, which would keep the context of the previous
+      // patched global in memory, creating a memory leak.
+      this.restorePatchedGlobals()
 
       return super.findPageComponents({ pathname, query, params, isAppPath })
     } catch (err) {