diff --git a/packages/vite/package.json b/packages/vite/package.json
index d3daf7938255da..1f837b12a3017b 100644
--- a/packages/vite/package.json
+++ b/packages/vite/package.json
@@ -86,6 +86,7 @@
     "@rollup/plugin-node-resolve": "15.0.1",
     "@rollup/plugin-typescript": "^11.0.0",
     "@rollup/pluginutils": "^5.0.2",
+    "@types/pnpapi": "^0.0.2",
     "acorn": "^8.8.2",
     "acorn-walk": "^8.2.0",
     "cac": "^6.7.14",
diff --git a/packages/vite/src/node/optimizer/index.ts b/packages/vite/src/node/optimizer/index.ts
index 62b3a9f14d7494..42620fc2ff7ab2 100644
--- a/packages/vite/src/node/optimizer/index.ts
+++ b/packages/vite/src/node/optimizer/index.ts
@@ -18,7 +18,6 @@ import {
   getHash,
   isOptimizable,
   lookupFile,
-  nestedResolveFrom,
   normalizeId,
   normalizePath,
   removeDir,
@@ -27,6 +26,7 @@ import {
 } from '../utils'
 import { transformWithEsbuild } from '../plugins/esbuild'
 import { ESBUILD_MODULES_TARGET } from '../constants'
+import { resolvePkgJsonPath } from '../packages'
 import { esbuildCjsExternalPlugin, esbuildDepPlugin } from './esbuildDepPlugin'
 import { scanImports } from './scan'
 export {
@@ -855,16 +855,30 @@ function createOptimizeDepsIncludeResolver(
     // 'foo > bar > baz' => 'foo > bar' & 'baz'
     const nestedRoot = id.substring(0, lastArrowIndex).trim()
     const nestedPath = id.substring(lastArrowIndex + 1).trim()
-    const basedir = nestedResolveFrom(
+    const basedir = nestedResolvePkgJsonPath(
       nestedRoot,
       config.root,
       config.resolve.preserveSymlinks,
-      ssr,
     )
     return await resolve(nestedPath, basedir, undefined, ssr)
   }
 }
 
+/**
+ * Like `resolvePkgJsonPath`, but supports resolving nested package names with '>'
+ */
+function nestedResolvePkgJsonPath(
+  id: string,
+  basedir: string,
+  preserveSymlinks = false,
+) {
+  const pkgs = id.split('>').map((pkg) => pkg.trim())
+  for (const pkg of pkgs) {
+    basedir = resolvePkgJsonPath(pkg, basedir, preserveSymlinks) || basedir
+  }
+  return basedir
+}
+
 export function newDepOptimizationProcessing(): DepOptimizationProcessing {
   let resolve: () => void
   const promise = new Promise((_resolve) => {
diff --git a/packages/vite/src/node/packages.ts b/packages/vite/src/node/packages.ts
index 1451d18853729a..a26c6e50a04350 100644
--- a/packages/vite/src/node/packages.ts
+++ b/packages/vite/src/node/packages.ts
@@ -1,9 +1,18 @@
 import fs from 'node:fs'
 import path from 'node:path'
-import { createDebugger, createFilter, resolveFrom } from './utils'
+import { createRequire } from 'node:module'
+import { createDebugger, createFilter, safeRealpathSync } from './utils'
 import type { ResolvedConfig } from './config'
 import type { Plugin } from './plugin'
 
+// eslint-disable-next-line @typescript-eslint/consistent-type-imports
+let pnp: typeof import('pnpapi') | undefined
+if (process.versions.pnp) {
+  try {
+    pnp = createRequire(import.meta.url)('pnpapi')
+  } catch {}
+}
+
 const isDebug = process.env.DEBUG
 const debug = createDebugger('vite:resolve-details', {
   onlyWhenFocused: true,
@@ -60,9 +69,9 @@ export function resolvePackageData(
       return pkg
     }
   }
-  let pkgPath: string | undefined
+  const pkgPath = resolvePkgJsonPath(id, basedir, preserveSymlinks)
+  if (!pkgPath) return null
   try {
-    pkgPath = resolveFrom(`${id}/package.json`, basedir, preserveSymlinks)
     pkg = loadPackageData(pkgPath, true, packageCache)
     if (packageCache) {
       packageCache.set(cacheKey!, pkg)
@@ -72,12 +81,8 @@ export function resolvePackageData(
     if (e instanceof SyntaxError) {
       isDebug && debug(`Parsing failed: ${pkgPath}`)
     }
-    // Ignore error for missing package.json
-    else if (e.code !== 'MODULE_NOT_FOUND') {
-      throw e
-    }
+    throw e
   }
-  return null
 }
 
 export function loadPackageData(
@@ -86,7 +91,7 @@ export function loadPackageData(
   packageCache?: PackageCache,
 ): PackageData {
   if (!preserveSymlinks) {
-    pkgPath = fs.realpathSync.native(pkgPath)
+    pkgPath = safeRealpathSync(pkgPath)
   }
 
   let cached: PackageData | undefined
@@ -178,3 +183,30 @@ export function watchPackageDataPlugin(config: ResolvedConfig): Plugin {
     },
   }
 }
+
+export function resolvePkgJsonPath(
+  pkgName: string,
+  basedir: string,
+  preserveSymlinks = false,
+): string | undefined {
+  if (pnp) {
+    const pkg = pnp.resolveToUnqualified(pkgName, basedir)
+    if (!pkg) return undefined
+    return path.join(pkg, 'package.json')
+  }
+
+  let root = basedir
+  while (root) {
+    const pkg = path.join(root, 'node_modules', pkgName, 'package.json')
+    try {
+      if (fs.existsSync(pkg)) {
+        return preserveSymlinks ? pkg : safeRealpathSync(pkg)
+      }
+    } catch {}
+    const nextRoot = path.dirname(root)
+    if (nextRoot === root) break
+    root = nextRoot
+  }
+
+  return undefined
+}
diff --git a/packages/vite/src/node/plugins/resolve.ts b/packages/vite/src/node/plugins/resolve.ts
index df75ced4f6da94..d1b43ce08e407f 100644
--- a/packages/vite/src/node/plugins/resolve.ts
+++ b/packages/vite/src/node/plugins/resolve.ts
@@ -1252,38 +1252,21 @@ function getRealPath(resolved: string, preserveSymlinks?: boolean): string {
 }
 
 /**
- * if importer was not resolved by vite's resolver previously
- * (when esbuild resolved it)
- * resolve importer's pkg and add to idToPkgMap
+ * Load closest `package.json` to `importer`
  */
 function resolvePkg(importer: string, options: InternalResolveOptions) {
-  const { root, preserveSymlinks, packageCache } = options
+  const { preserveSymlinks, packageCache } = options
 
   if (importer.includes('\x00')) {
     return null
   }
 
-  const possiblePkgIds: string[] = []
-  for (let prevSlashIndex = -1; ; ) {
-    const slashIndex = importer.indexOf(isWindows ? '\\' : '/', prevSlashIndex)
-    if (slashIndex < 0) {
-      break
-    }
-
-    prevSlashIndex = slashIndex + 1
-
-    const possiblePkgId = importer.slice(0, slashIndex)
-    possiblePkgIds.push(possiblePkgId)
-  }
-
-  let pkg: PackageData | undefined
-  possiblePkgIds.reverse().find((pkgId) => {
-    pkg = resolvePackageData(pkgId, root, preserveSymlinks, packageCache)!
-    return pkg
-  })!
-
-  if (pkg) {
+  const pkgPath = lookupFile(importer, ['package.json'], { pathOnly: true })
+  if (pkgPath) {
+    const pkg = loadPackageData(pkgPath, preserveSymlinks, packageCache)
     idToPkgMap.set(importer, pkg)
+    return pkg
   }
-  return pkg
+
+  return undefined
 }
diff --git a/packages/vite/src/node/ssr/ssrExternal.ts b/packages/vite/src/node/ssr/ssrExternal.ts
index ce08b020d17fbf..f3ecb56f2a7312 100644
--- a/packages/vite/src/node/ssr/ssrExternal.ts
+++ b/packages/vite/src/node/ssr/ssrExternal.ts
@@ -11,9 +11,9 @@ import {
   isDefined,
   lookupFile,
   normalizePath,
-  resolveFrom,
 } from '../utils'
 import type { Logger, ResolvedConfig } from '..'
+import { resolvePkgJsonPath } from '../packages'
 
 const debug = createDebugger('vite:ssr-external')
 
@@ -256,16 +256,16 @@ function cjsSsrCollectExternals(
       // which returns with '/', require.resolve returns with '\\'
       requireEntry = normalizePath(_require.resolve(id, { paths: [root] }))
     } catch (e) {
-      try {
-        // no main entry, but deep imports may be allowed
-        const pkgPath = resolveFrom(`${id}/package.json`, root)
+      // no main entry, but deep imports may be allowed
+      const pkgPath = resolvePkgJsonPath(id, root)
+      if (pkgPath) {
         if (pkgPath.includes('node_modules')) {
           ssrExternals.add(id)
         } else {
           depsToTrace.add(path.dirname(pkgPath))
         }
         continue
-      } catch {}
+      }
 
       // resolve failed, assume include
       debug(`Failed to resolve entries for package "${id}"\n`, e)
@@ -277,8 +277,10 @@ function cjsSsrCollectExternals(
     }
     // trace the dependencies of linked packages
     else if (!esmEntry.includes('node_modules')) {
-      const pkgPath = resolveFrom(`${id}/package.json`, root)
-      depsToTrace.add(path.dirname(pkgPath))
+      const pkgPath = resolvePkgJsonPath(id, root)
+      if (pkgPath) {
+        depsToTrace.add(path.dirname(pkgPath))
+      }
     }
     // has separate esm/require entry, assume require entry is cjs
     else if (esmEntry !== requireEntry) {
@@ -288,7 +290,11 @@ function cjsSsrCollectExternals(
     // or are there others like SystemJS / AMD that we'd need to handle?
     // for now, we'll just leave this as is
     else if (/\.m?js$/.test(esmEntry)) {
-      const pkgPath = resolveFrom(`${id}/package.json`, root)
+      const pkgPath = resolvePkgJsonPath(id, root)
+      if (!pkgPath) {
+        continue
+      }
+
       const pkgContent = fs.readFileSync(pkgPath, 'utf-8')
 
       if (!pkgContent) {
diff --git a/packages/vite/src/node/utils.ts b/packages/vite/src/node/utils.ts
index 1ff7291f84a319..02b7f6d48c80fe 100644
--- a/packages/vite/src/node/utils.ts
+++ b/packages/vite/src/node/utils.ts
@@ -127,15 +127,9 @@ export function isOptimizable(
 export const bareImportRE = /^[\w@](?!.*:\/\/)/
 export const deepImportRE = /^([^@][^/]*)\/|^(@[^/]+\/[^/]+)\//
 
-export let isRunningWithYarnPnp: boolean
-
 // TODO: use import()
 const _require = createRequire(import.meta.url)
 
-try {
-  isRunningWithYarnPnp = Boolean(_require('pnpapi'))
-} catch {}
-
 const ssrExtensions = ['.js', '.cjs', '.json', '.node']
 
 export function resolveFrom(
@@ -149,29 +143,10 @@ export function resolveFrom(
     paths: [],
     extensions: ssr ? ssrExtensions : DEFAULT_EXTENSIONS,
     // necessary to work with pnpm
-    preserveSymlinks: preserveSymlinks || isRunningWithYarnPnp || false,
+    preserveSymlinks: preserveSymlinks || !!process.versions.pnp || false,
   })
 }
 
-/**
- * like `resolveFrom` but supports resolving `>` path in `id`,
- * for example: `foo > bar > baz`
- */
-export function nestedResolveFrom(
-  id: string,
-  basedir: string,
-  preserveSymlinks = false,
-  ssr = false,
-): string {
-  const pkgs = id.split('>').map((pkg) => pkg.trim())
-  try {
-    for (const pkg of pkgs) {
-      basedir = resolveFrom(pkg, basedir, preserveSymlinks, ssr)
-    }
-  } catch {}
-  return basedir
-}
-
 // set in bin/vite.js
 const filter = process.env.VITE_DEBUG_FILTER
 
@@ -607,6 +582,13 @@ export const removeDir = isWindows
     }
 export const renameDir = isWindows ? promisify(gracefulRename) : fs.renameSync
 
+// `fs.realpathSync.native` resolves differently in Windows network drive,
+// causing file read errors. skip for now.
+// https://github.com/nodejs/node/issues/37737
+export const safeRealpathSync = isWindows
+  ? fs.realpathSync
+  : fs.realpathSync.native
+
 export function ensureWatchedFile(
   watcher: FSWatcher,
   file: string | null,
diff --git a/pnpm-lock.yaml b/pnpm-lock.yaml
index 97c07b405e12ce..1fd4807dde3821 100644
--- a/pnpm-lock.yaml
+++ b/pnpm-lock.yaml
@@ -177,6 +177,7 @@ importers:
       '@rollup/plugin-node-resolve': 15.0.1
       '@rollup/plugin-typescript': ^11.0.0
       '@rollup/pluginutils': ^5.0.2
+      '@types/pnpapi': ^0.0.2
       acorn: ^8.8.2
       acorn-walk: ^8.2.0
       cac: ^6.7.14
@@ -246,6 +247,7 @@ importers:
       '@rollup/plugin-node-resolve': 15.0.1_rollup@3.20.0
       '@rollup/plugin-typescript': 11.0.0_rollup@3.20.0+tslib@2.5.0
       '@rollup/pluginutils': 5.0.2_rollup@3.20.0
+      '@types/pnpapi': 0.0.2
       acorn: 8.8.2
       acorn-walk: 8.2.0_acorn@8.8.2
       cac: 6.7.14
@@ -3491,6 +3493,10 @@ packages:
     resolution: {integrity: sha512-O397rnSS9iQI4OirieAtsDqvCj4+3eY1J+EPdNTKuHuRWIfUoGyzX294o8C4KJYaLqgSrd2o60c5EqCU8Zv02g==}
     dev: true
 
+  /@types/pnpapi/0.0.2:
+    resolution: {integrity: sha512-2lqsQt1iXkiTqwuzw2SS50iduoPZNpV/ou4/vJD443C0weF63Gqd3ErGS811CBNMzLO64zVJ+tiyh+4yimdYkg==}
+    dev: true
+
   /@types/prompts/2.4.2:
     resolution: {integrity: sha512-TwNx7qsjvRIUv/BCx583tqF5IINEVjCNqg9ofKHRlSoUHE62WBHrem4B1HGXcIrG511v29d1kJ9a/t2Esz7MIg==}
     dependencies: