diff --git a/packages/plugin-vue-jsx/index.js b/packages/plugin-vue-jsx/index.js
index ac8e554c77ee59..ea36b0b1d91219 100644
--- a/packages/plugin-vue-jsx/index.js
+++ b/packages/plugin-vue-jsx/index.js
@@ -2,8 +2,9 @@
 const babel = require('@babel/core')
 const jsx = require('@vue/babel-plugin-jsx')
 const importMeta = require('@babel/plugin-syntax-import-meta')
-const { createFilter } = require('@rollup/pluginutils')
+const { createFilter, normalizePath } = require('@rollup/pluginutils')
 const hash = require('hash-sum')
+const path = require('path')
 
 const ssrRegisterHelperId = '/__vue-jsx-ssr-register-helper'
 const ssrRegisterHelperCode =
@@ -39,6 +40,7 @@ function ssrRegisterHelper(comp, filename) {
  * @returns {import('vite').Plugin}
  */
 function vueJsxPlugin(options = {}) {
+  let root = ''
   let needHmr = false
   let needSourceMap = true
 
@@ -63,6 +65,7 @@ function vueJsxPlugin(options = {}) {
     configResolved(config) {
       needHmr = config.command === 'serve' && !config.isProduction
       needSourceMap = config.command === 'serve' || !!config.build.sourcemap
+      root = config.root
     },
 
     resolveId(id) {
@@ -226,9 +229,10 @@ function vueJsxPlugin(options = {}) {
           }
 
           if (ssr) {
+            const normalizedId = normalizePath(path.relative(root, id))
             let ssrInjectCode =
               `\nimport { ssrRegisterHelper } from "${ssrRegisterHelperId}"` +
-              `\nconst __moduleId = ${JSON.stringify(id)}`
+              `\nconst __moduleId = ${JSON.stringify(normalizedId)}`
             for (const { local } of hotComponents) {
               ssrInjectCode += `\nssrRegisterHelper(${local}, __moduleId)`
             }
diff --git a/packages/plugin-vue/src/main.ts b/packages/plugin-vue/src/main.ts
index 98bca03db6f081..b6dfd03714cefd 100644
--- a/packages/plugin-vue/src/main.ts
+++ b/packages/plugin-vue/src/main.ts
@@ -8,6 +8,7 @@ import {
   setDescriptor
 } from './utils/descriptorCache'
 import { PluginContext, TransformPluginContext } from 'rollup'
+import { normalizePath } from '@rollup/pluginutils'
 import { resolveScript } from './script'
 import { transformTemplateInMain } from './template'
 import { isOnlyTemplateChanged, isEqualBlock } from './handleHotUpdate'
@@ -143,13 +144,16 @@ export async function transformMain(
 
   // SSR module registration by wrapping user setup
   if (ssr) {
+    const normalizedFilename = normalizePath(
+      path.relative(options.root, filename)
+    )
     output.push(
       `import { useSSRContext as __vite_useSSRContext } from 'vue'`,
       `const _sfc_setup = _sfc_main.setup`,
       `_sfc_main.setup = (props, ctx) => {`,
       `  const ssrContext = __vite_useSSRContext()`,
       `  ;(ssrContext.modules || (ssrContext.modules = new Set())).add(${JSON.stringify(
-        filename
+        normalizedFilename
       )})`,
       `  return _sfc_setup ? _sfc_setup(props, ctx) : undefined`,
       `}`
diff --git a/packages/vite/src/node/ssr/ssrManifestPlugin.ts b/packages/vite/src/node/ssr/ssrManifestPlugin.ts
index 93d2d19a503ee4..d137f727b51847 100644
--- a/packages/vite/src/node/ssr/ssrManifestPlugin.ts
+++ b/packages/vite/src/node/ssr/ssrManifestPlugin.ts
@@ -1,3 +1,5 @@
+import { relative } from 'path'
+import { normalizePath } from '@rollup/pluginutils'
 import { ResolvedConfig } from '..'
 import { Plugin } from '../plugin'
 import { chunkToEmittedCssFileMap } from '../plugins/css'
@@ -21,7 +23,9 @@ export function ssrManifestPlugin(config: ResolvedConfig): Plugin {
             : chunkToEmittedCssFileMap.get(chunk)
           const assetFiles = chunkToEmittedAssetsMap.get(chunk)
           for (const id in chunk.modules) {
-            const mappedChunks = ssrManifest[id] || (ssrManifest[id] = [])
+            const normalizedId = normalizePath(relative(config.root, id))
+            const mappedChunks =
+              ssrManifest[normalizedId] || (ssrManifest[normalizedId] = [])
             if (!chunk.isEntry) {
               mappedChunks.push(base + chunk.fileName)
             }