diff --git a/packages/playground/resolve/__tests__/resolve.spec.ts b/packages/playground/resolve/__tests__/resolve.spec.ts
index 46f8f6138b39a4..2deb2fab7f8d40 100644
--- a/packages/playground/resolve/__tests__/resolve.spec.ts
+++ b/packages/playground/resolve/__tests__/resolve.spec.ts
@@ -61,14 +61,8 @@ test('dont add extension to directory name (./dir-with-ext.js/index.js)', async
   expect(await page.textContent('.dir-with-ext')).toMatch('[success]')
 })
 
-test('resolve to the `browser` field instead of `module` when the importer is a `require` call', async () => {
-  expect(
-    await page.textContent('.require-pkg-with-browser-and-module-field')
-  ).toMatch('[success]')
-})
-
-test('resolve to the `main` field instead of `module` when the importer is a `require` call', async () => {
-  expect(await page.textContent('.require-pkg-with-esm-entries')).toMatch(
+test('do not resolve to the `module` field if the importer is a `require` call', async () => {
+  expect(await page.textContent('.require-pkg-with-module-field')).toMatch(
     '[success]'
   )
 })
diff --git a/packages/playground/resolve/index.html b/packages/playground/resolve/index.html
index 2478c89b495f49..1920ebb675d24c 100644
--- a/packages/playground/resolve/index.html
+++ b/packages/playground/resolve/index.html
@@ -58,17 +58,8 @@ <h2>Resolve file name containing dot</h2>
 <h2>Browser Field</h2>
 <p class="browser">fail</p>
 
-<h2>
-  Resolve to the `browser` field instead of `module` when the importer is a
-  `require` call
-</h2>
-<p class="require-pkg-with-browser-and-module-field">fail</p>
-
-<h2>
-  Resolve to the `main` field instead of `module` when the importer is a
-  `require` call
-</h2>
-<p class="require-pkg-with-esm-entries">fail</p>
+<h2>Don't resolve to the `module` field if the importer is a `require` call</h2>
+<p class="require-pkg-with-module-field">fail</p>
 
 <h2>CSS Entry</h2>
 <p class="css"></p>
@@ -194,11 +185,8 @@ <h2>resolve package that contains # in path</h2>
     text('.browser', main)
   }
 
-  import { msg as requireBrowserMsg } from 'require-pkg-with-browser-and-module-field'
-  text('.require-pkg-with-browser-and-module-field', requireBrowserMsg)
-
-  import { msg as requireMainMsg } from 'require-pkg-with-esm-entries'
-  text('.require-pkg-with-esm-entries', requireMainMsg)
+  import { msg as requireButWithModuleFieldMsg } from 'require-pkg-with-module-field'
+  text('.require-pkg-with-module-field', requireButWithModuleFieldMsg)
 
   import { msg as customExtMsg } from './custom-ext'
   text('.custom-ext', customExtMsg)
diff --git a/packages/playground/resolve/package.json b/packages/playground/resolve/package.json
index 4b8d497b3dbb27..dda4476bc6ae82 100644
--- a/packages/playground/resolve/package.json
+++ b/packages/playground/resolve/package.json
@@ -12,8 +12,7 @@
     "@babel/runtime": "^7.16.0",
     "es5-ext": "0.10.53",
     "normalize.css": "^8.0.1",
-    "require-pkg-with-browser-and-module-field": "link:./require-pkg-with-browser-and-module-field",
-    "require-pkg-with-esm-entries": "link:./require-pkg-with-esm-entries",
+    "require-pkg-with-module-field": "link:./require-pkg-with-module-field",
     "resolve-browser-field": "link:./browser-field",
     "resolve-custom-condition": "link:./custom-condition",
     "resolve-custom-main-field": "link:./custom-main-field",
diff --git a/packages/playground/resolve/require-pkg-with-browser-and-module-field/index.cjs b/packages/playground/resolve/require-pkg-with-browser-and-module-field/index.cjs
deleted file mode 100644
index 86d3360ab38dcb..00000000000000
--- a/packages/playground/resolve/require-pkg-with-browser-and-module-field/index.cjs
+++ /dev/null
@@ -1,8 +0,0 @@
-const dep = require('./dep.cjs')
-
-const msg =
-  dep === '1.111222233334444555566e+21'
-    ? '[success] require-pkg-with-browser-and-module-field'
-    : '[failed] require-pkg-with-browser-and-module-field'
-
-exports.msg = msg
diff --git a/packages/playground/resolve/require-pkg-with-esm-entries/index.cjs b/packages/playground/resolve/require-pkg-with-esm-entries/index.cjs
deleted file mode 100644
index 55958fbdba26ee..00000000000000
--- a/packages/playground/resolve/require-pkg-with-esm-entries/index.cjs
+++ /dev/null
@@ -1,9 +0,0 @@
-const fromEvent = require('callbag-from-event')
-
-const msg =
-  // should be the exported function instead of the ES Module record (`{ default: ... }`)
-  typeof fromEvent === 'function'
-    ? '[success] require-pkg-with-esm-entries'
-    : '[failed] require-pkg-with-esm-entries'
-
-exports.msg = msg
diff --git a/packages/playground/resolve/require-pkg-with-esm-entries/package.json b/packages/playground/resolve/require-pkg-with-esm-entries/package.json
deleted file mode 100644
index b845364bb6f19a..00000000000000
--- a/packages/playground/resolve/require-pkg-with-esm-entries/package.json
+++ /dev/null
@@ -1,9 +0,0 @@
-{
-  "name": "require-pkg-with-esm-entries",
-  "private": true,
-  "version": "1.0.0",
-  "main": "./index.cjs",
-  "dependencies": {
-    "callbag-from-event": "1.3.0"
-  }
-}
diff --git a/packages/playground/resolve/require-pkg-with-browser-and-module-field/dep.cjs b/packages/playground/resolve/require-pkg-with-module-field/dep.cjs
similarity index 100%
rename from packages/playground/resolve/require-pkg-with-browser-and-module-field/dep.cjs
rename to packages/playground/resolve/require-pkg-with-module-field/dep.cjs
diff --git a/packages/playground/resolve/require-pkg-with-module-field/index.cjs b/packages/playground/resolve/require-pkg-with-module-field/index.cjs
new file mode 100644
index 00000000000000..da215f306d1ac1
--- /dev/null
+++ b/packages/playground/resolve/require-pkg-with-module-field/index.cjs
@@ -0,0 +1,8 @@
+const dep = require('./dep.cjs')
+
+const msg =
+  dep === '1.111222233334444555566e+21'
+    ? '[success] require-pkg-with-module-field'
+    : '[failed] require-pkg-with-module-field'
+
+exports.msg = msg
diff --git a/packages/playground/resolve/require-pkg-with-browser-and-module-field/package.json b/packages/playground/resolve/require-pkg-with-module-field/package.json
similarity index 68%
rename from packages/playground/resolve/require-pkg-with-browser-and-module-field/package.json
rename to packages/playground/resolve/require-pkg-with-module-field/package.json
index 2a0419b331c407..e409343a7567d5 100644
--- a/packages/playground/resolve/require-pkg-with-browser-and-module-field/package.json
+++ b/packages/playground/resolve/require-pkg-with-module-field/package.json
@@ -1,5 +1,5 @@
 {
-  "name": "require-pkg-with-browser-and-module-field",
+  "name": "require-pkg-with-module-field",
   "private": true,
   "version": "1.0.0",
   "main": "./index.cjs",
diff --git a/packages/playground/resolve/vite.config.js b/packages/playground/resolve/vite.config.js
index c1282f4ffc789d..0550d1ecf6f044 100644
--- a/packages/playground/resolve/vite.config.js
+++ b/packages/playground/resolve/vite.config.js
@@ -42,9 +42,6 @@ module.exports = {
     }
   ],
   optimizeDeps: {
-    include: [
-      'require-pkg-with-browser-and-module-field',
-      'require-pkg-with-esm-entries'
-    ]
+    include: ['require-pkg-with-module-field']
   }
 }
diff --git a/packages/vite/src/node/constants.ts b/packages/vite/src/node/constants.ts
index 1741bf2dd7a94b..9612cd8c96460d 100644
--- a/packages/vite/src/node/constants.ts
+++ b/packages/vite/src/node/constants.ts
@@ -6,21 +6,6 @@ export const DEFAULT_MAIN_FIELDS = [
   'jsnext'
 ]
 
-/**
- * A non-exhaustive list of known-to-be-ES-module entry names.
- * From <https://github.com/stereobooster/package.json#package-bundlers>
- */
-export const KNOWN_ESM_MAIN_FIELDS = [
-  'module',
-  'jsnext:main',
-  'jsnext',
-  'esnext',
-  'es2015',
-  'es2020',
-  'fesm2015',
-  'fesm2020'
-]
-
 export const DEFAULT_EXTENSIONS = [
   '.mjs',
   '.js',
diff --git a/packages/vite/src/node/plugins/resolve.ts b/packages/vite/src/node/plugins/resolve.ts
index 10e2989af1114f..1b59503a9d43ed 100644
--- a/packages/vite/src/node/plugins/resolve.ts
+++ b/packages/vite/src/node/plugins/resolve.ts
@@ -7,7 +7,6 @@ import {
   SPECIAL_QUERY_RE,
   DEFAULT_EXTENSIONS,
   DEFAULT_MAIN_FIELDS,
-  KNOWN_ESM_MAIN_FIELDS,
   OPTIMIZABLE_ENTRY_RE,
   DEP_VERSION_RE
 } from '../constants'
@@ -778,11 +777,6 @@ export function resolvePackageEntry(
 
     if (!entryPoint || entryPoint.endsWith('.mjs')) {
       for (const field of options.mainFields || DEFAULT_MAIN_FIELDS) {
-        // If the initiator is a `require` call, don't use the ESM entries
-        if (options.isRequire && KNOWN_ESM_MAIN_FIELDS.includes(field)) {
-          continue
-        }
-
         if (typeof data[field] === 'string') {
           entryPoint = data[field]
           break
diff --git a/pnpm-lock.yaml b/pnpm-lock.yaml
index fbc05e51fbfc7a..09d96eb30938d7 100644
--- a/pnpm-lock.yaml
+++ b/pnpm-lock.yaml
@@ -461,8 +461,7 @@ importers:
       '@babel/runtime': ^7.16.0
       es5-ext: 0.10.53
       normalize.css: ^8.0.1
-      require-pkg-with-browser-and-module-field: link:./require-pkg-with-browser-and-module-field
-      require-pkg-with-esm-entries: link:./require-pkg-with-esm-entries
+      require-pkg-with-module-field: link:./require-pkg-with-module-field
       resolve-browser-field: link:./browser-field
       resolve-custom-condition: link:./custom-condition
       resolve-custom-main-field: link:./custom-main-field
@@ -473,8 +472,7 @@ importers:
       '@babel/runtime': 7.16.5
       es5-ext: 0.10.53
       normalize.css: 8.0.1
-      require-pkg-with-browser-and-module-field: link:require-pkg-with-browser-and-module-field
-      require-pkg-with-esm-entries: link:require-pkg-with-esm-entries
+      require-pkg-with-module-field: link:require-pkg-with-module-field
       resolve-browser-field: link:browser-field
       resolve-custom-condition: link:custom-condition
       resolve-custom-main-field: link:custom-main-field
@@ -506,18 +504,12 @@ importers:
   packages/playground/resolve/inline-package:
     specifiers: {}
 
-  packages/playground/resolve/require-pkg-with-browser-and-module-field:
+  packages/playground/resolve/require-pkg-with-module-field:
     specifiers:
       bignumber.js: 9.0.2
     dependencies:
       bignumber.js: 9.0.2
 
-  packages/playground/resolve/require-pkg-with-esm-entries:
-    specifiers:
-      callbag-from-event: 1.3.0
-    dependencies:
-      callbag-from-event: 1.3.0
-
   packages/playground/ssr-deps:
     specifiers:
       bcrypt: ^5.0.1
@@ -3497,16 +3489,6 @@ packages:
       get-intrinsic: 1.1.1
     dev: true
 
-  /callbag-from-event/1.3.0:
-    resolution: {integrity: sha512-cAu82hKKFmMtKTmd50p/nlMfs1oKz+PGUZmmwhbzPbw4YtjNgTKg6pXjpcQprhBQdrqg/v8pHcAS8Qs6X7r8fw==}
-    dependencies:
-      callbag: 1.5.0
-    dev: false
-
-  /callbag/1.5.0:
-    resolution: {integrity: sha512-PH3id0HEb/cNS+BehYlF4Z5wzjKAIUao6ab2hWtMs2bi6aW+0PXl0jymqwnFyT2cQO2h30ggUgpQlmzOpAIKNg==}
-    dev: false
-
   /callsites/3.1.0:
     resolution: {integrity: sha512-P8BjAsXvZS+VIDUI11hHCQEv74YT67YUi5JJFNWIqL235sBmjX4+qx9Muvls5ivyNENctx46xQLQ3aTuE7ssaQ==}
     engines: {node: '>=6'}