diff --git a/packages/vite/src/node/config.ts b/packages/vite/src/node/config.ts
index 6440dc5a058457..f8349751505fa8 100644
--- a/packages/vite/src/node/config.ts
+++ b/packages/vite/src/node/config.ts
@@ -1001,6 +1001,7 @@ async function bundleConfigFile(
             dedupe: [],
             extensions: DEFAULT_EXTENSIONS,
             preserveSymlinks: false,
+            packageCache: new Map(),
           }
 
           // externalize bare imports
diff --git a/packages/vite/src/node/optimizer/index.ts b/packages/vite/src/node/optimizer/index.ts
index c4a3f199f291d9..b1ed24f10a254b 100644
--- a/packages/vite/src/node/optimizer/index.ts
+++ b/packages/vite/src/node/optimizer/index.ts
@@ -878,6 +878,7 @@ function createOptimizeDepsIncludeResolver(
     scan: true,
     ssrOptimizeCheck: ssr,
     ssrConfig: config.ssr,
+    packageCache: new Map(),
   })
   return async (id: string) => {
     const lastArrowIndex = id.lastIndexOf('>')
diff --git a/packages/vite/src/node/plugins/assetImportMetaUrl.ts b/packages/vite/src/node/plugins/assetImportMetaUrl.ts
index 7a22de3e31814b..6872de5249e014 100644
--- a/packages/vite/src/node/plugins/assetImportMetaUrl.ts
+++ b/packages/vite/src/node/plugins/assetImportMetaUrl.ts
@@ -10,6 +10,7 @@ import {
   slash,
   transformStableResult,
 } from '../utils'
+import { CLIENT_ENTRY } from '../constants'
 import { fileToUrl } from './asset'
 import { preloadHelperId } from './importAnalysisBuild'
 
@@ -33,6 +34,7 @@ export function assetImportMetaUrlPlugin(config: ResolvedConfig): Plugin {
       if (
         !options?.ssr &&
         id !== preloadHelperId &&
+        id !== CLIENT_ENTRY &&
         code.includes('new URL') &&
         code.includes(`import.meta.url`)
       ) {