diff --git a/packages/vite/src/node/server/middlewares/transform.ts b/packages/vite/src/node/server/middlewares/transform.ts
index ebc1f3ce5f5bf7..81602784e229ba 100644
--- a/packages/vite/src/node/server/middlewares/transform.ts
+++ b/packages/vite/src/node/server/middlewares/transform.ts
@@ -98,11 +98,15 @@ export function transformMiddleware(
         return
       }
     }
-
-    let url = decodeURI(removeTimestampQuery(req.url!)).replace(
-      NULL_BYTE_PLACEHOLDER,
-      '\0'
-    )
+    let url: string
+    try {
+      url = decodeURI(removeTimestampQuery(req.url!)).replace(
+        NULL_BYTE_PLACEHOLDER,
+        '\0'
+      )
+    } catch (e) {
+      return next(e)
+    }
 
     const withoutQuery = cleanUrl(url)