diff --git a/packages/vite/src/node/optimizer/esbuildDepPlugin.ts b/packages/vite/src/node/optimizer/esbuildDepPlugin.ts
index 20b808b1dc7ec7..57e67c2b47a166 100644
--- a/packages/vite/src/node/optimizer/esbuildDepPlugin.ts
+++ b/packages/vite/src/node/optimizer/esbuildDepPlugin.ts
@@ -29,6 +29,8 @@ const externalTypes = [
   'stylus',
   'pcss',
   'postcss',
+  // wasm
+  'wasm',
   // known SFC types
   'vue',
   'svelte',
diff --git a/packages/vite/src/node/optimizer/scan.ts b/packages/vite/src/node/optimizer/scan.ts
index f1f698a15258a9..5a6c55ea0a5746 100644
--- a/packages/vite/src/node/optimizer/scan.ts
+++ b/packages/vite/src/node/optimizer/scan.ts
@@ -419,10 +419,10 @@ function esbuildScanPlugin(
       // they are done after the bare import resolve because a package name
       // may end with these extensions
 
-      // css & json
+      // css & json & wasm
       build.onResolve(
         {
-          filter: /\.(css|less|sass|scss|styl|stylus|pcss|postcss|json)$/
+          filter: /\.(css|less|sass|scss|styl|stylus|pcss|postcss|json|wasm)$/
         },
         externalUnlessEntry
       )