diff --git a/packages/core/useBase64/index.md b/packages/core/useBase64/index.md
index 9bf36a16cc0..077e527b035 100644
--- a/packages/core/useBase64/index.md
+++ b/packages/core/useBase64/index.md
@@ -4,7 +4,7 @@ category: Utilities
 
 # useBase64
 
-Reactive base64 transforming. Supports plain text, buffer, files, canvas and images.
+Reactive base64 transforming. Supports plain text, buffer, files, canvas, objects, maps, sets and images.
 
 ## Usage
 
@@ -16,3 +16,7 @@ const text = ref('')
 
 const { base64 } = useBase64(text)
 ```
+
+If you use object, array, map or set you can provide serializer in options. Otherwise, your data will be serialized by default serializer.
+Objects and arrays will be transformed in string by JSON.stringify. Map and set will be transformed in object and array respectively before stringify.
+
diff --git a/packages/core/useBase64/index.test.ts b/packages/core/useBase64/index.test.ts
new file mode 100644
index 00000000000..ae9f96ffd81
--- /dev/null
+++ b/packages/core/useBase64/index.test.ts
@@ -0,0 +1,67 @@
+import { useBase64 } from '@vueuse/core'
+import { describe, expect } from 'vitest'
+
+function decode(encoded: string) {
+  const decodedStr = Buffer.from(encoded.split(',')[1], 'base64').toString('utf-8')
+
+  if (!decodedStr)
+    return ''
+
+  return JSON.parse(decodedStr)
+}
+
+describe('useBase64', () => {
+  it('should work with record', async () => {
+    const template = { test: 5 }
+
+    const { promise, base64 } = useBase64(template)
+
+    await promise.value
+
+    expect(decode(base64.value)).toEqual(template)
+  })
+
+  it('should work with map and default serialize function', async () => {
+    const map = new Map([['test', 1]])
+
+    const { promise, base64 } = useBase64(map)
+
+    await promise.value
+
+    expect(decode(base64.value)).toEqual(Object.fromEntries(map))
+  })
+
+  it('should work with set', async () => {
+    const set = new Set([1])
+
+    const { promise, base64 } = useBase64(set)
+
+    await promise.value
+
+    expect(decode(base64.value)).toEqual(Array.from(set))
+  })
+
+  it('should work with array', async () => {
+    const arr = [1, 2, 3]
+
+    const { promise, base64 } = useBase64(arr)
+
+    await promise.value
+
+    expect(decode(base64.value)).toEqual(arr)
+  })
+
+  it('should work with custom serialize function', async () => {
+    const arr = [1, 2, 3]
+
+    const serializer = (arr: number[]) => {
+      return JSON.stringify(arr.map(el => el * 2))
+    }
+
+    const { promise, base64 } = useBase64(arr, { serializer })
+
+    await promise.value
+
+    expect(decode(base64.value)).toEqual(JSON.parse(serializer(arr)))
+  })
+})
diff --git a/packages/core/useBase64/index.ts b/packages/core/useBase64/index.ts
index b02a1f882ec..d8a5bde7f40 100644
--- a/packages/core/useBase64/index.ts
+++ b/packages/core/useBase64/index.ts
@@ -1,7 +1,8 @@
 import type { Ref } from 'vue-demi'
-import { ref, unref, watch } from 'vue-demi'
+import { isRef, ref, unref, watch } from 'vue-demi'
 import type { MaybeRef } from '@vueuse/shared'
 import { isClient } from '@vueuse/shared'
+import { getDefaultSerialization } from './serialization'
 
 export interface ToDataURLOptions {
   /**
@@ -14,6 +15,10 @@ export interface ToDataURLOptions {
   quality?: any
 }
 
+export interface UseBase64ObjectOptions<T> {
+  serializer: (v: T) => string
+}
+
 export interface UseBase64Return {
   base64: Ref<string>
   promise: Ref<Promise<string>>
@@ -25,6 +30,10 @@ export function useBase64(target: MaybeRef<Blob>): UseBase64Return
 export function useBase64(target: MaybeRef<ArrayBuffer>): UseBase64Return
 export function useBase64(target: MaybeRef<HTMLCanvasElement>, options?: ToDataURLOptions): UseBase64Return
 export function useBase64(target: MaybeRef<HTMLImageElement>, options?: ToDataURLOptions): UseBase64Return
+export function useBase64<T extends Record<string, unknown>>(target: MaybeRef<T>, options?: UseBase64ObjectOptions<T>): UseBase64Return
+export function useBase64<T extends Map<string, unknown>>(target: MaybeRef<T>, options?: UseBase64ObjectOptions<T>): UseBase64Return
+export function useBase64<T extends Set<unknown>>(target: MaybeRef<T>, options?: UseBase64ObjectOptions<T>): UseBase64Return
+export function useBase64<T>(target: MaybeRef<T[]>, options?: UseBase64ObjectOptions<T[]>): UseBase64Return
 export function useBase64(
   target: any,
   options?: any,
@@ -39,12 +48,21 @@ export function useBase64(
     promise.value = new Promise<string>((resolve, reject) => {
       try {
         const _target = unref(target)
-        // undefined or null
-        if (_target === undefined || _target === null) { resolve('') }
-        else if (typeof _target === 'string') { resolve(blobToBase64(new Blob([_target], { type: 'text/plain' }))) }
-        else if (_target instanceof Blob) { resolve(blobToBase64(_target)) }
-        else if (_target instanceof ArrayBuffer) { resolve(window.btoa(String.fromCharCode(...new Uint8Array(_target)))) }
-        else if (_target instanceof HTMLCanvasElement) { resolve(_target.toDataURL(options?.type, options?.quality)) }
+        if (_target == null) {
+          resolve('')
+        }
+        else if (typeof _target === 'string') {
+          resolve(blobToBase64(new Blob([_target], { type: 'text/plain' })))
+        }
+        else if (_target instanceof Blob) {
+          resolve(blobToBase64(_target))
+        }
+        else if (_target instanceof ArrayBuffer) {
+          resolve(window.btoa(String.fromCharCode(...new Uint8Array(_target))))
+        }
+        else if (_target instanceof HTMLCanvasElement) {
+          resolve(_target.toDataURL(options?.type, options?.quality))
+        }
         else if (_target instanceof HTMLImageElement) {
           const img = _target.cloneNode(false) as HTMLImageElement
           img.crossOrigin = 'Anonymous'
@@ -57,6 +75,13 @@ export function useBase64(
             resolve(canvas.toDataURL(options?.type, options?.quality))
           }).catch(reject)
         }
+        else if (typeof _target === 'object') {
+          const _serializeFn = options?.serializer || getDefaultSerialization(_target)
+
+          const serialized = _serializeFn(_target)
+
+          return resolve(blobToBase64(new Blob([serialized], { type: 'application/json' })))
+        }
         else {
           reject(new Error('target is unsupported types'))
         }
@@ -69,7 +94,10 @@ export function useBase64(
     return promise.value
   }
 
-  watch(target, execute, { immediate: true })
+  if (isRef(target))
+    watch(target, execute, { immediate: true })
+  else
+    execute()
 
   return {
     base64,
diff --git a/packages/core/useBase64/serialization.ts b/packages/core/useBase64/serialization.ts
new file mode 100644
index 00000000000..c95773193b7
--- /dev/null
+++ b/packages/core/useBase64/serialization.ts
@@ -0,0 +1,21 @@
+const defaults = {
+  array: (v: unknown[]) => JSON.stringify(v),
+  object: (v: Record<string, unknown>) => JSON.stringify(v),
+  set: (v: Set<unknown>) => JSON.stringify(Array.from(v)),
+  map: (v: Map<string, unknown>) => JSON.stringify(Object.fromEntries(v)),
+  null: () => '',
+}
+
+export function getDefaultSerialization<T extends Object>(target: T) {
+  if (!target)
+    return defaults.null
+
+  if (target instanceof Map)
+    return defaults.map
+  else if (target instanceof Set)
+    return defaults.set
+  else if (Array.isArray(target))
+    return defaults.array
+  else
+    return defaults.object
+}